法莫替丁(信法丁) Famotidine
【作用与用途】
本品为组织胺H2受体拮抗剂。对胃酸分泌具有明显的抑制作用，其作用强度比西咪替丁强30多倍，比雷尼替丁强6-10倍，临床用于胃及十二指肠溃疡、应激性溃疡、急性胃粘膜出血、胃泌素瘤以及反流性食道炎等。
【用法】
成人口服：每次20mg，一日2次，或一次40mg，临睡前服用，4-6周为一疗程。溃疡愈后的维持量可减半，肾功能不全者应遵医嘱调整剂量。
【副作用】
少数患者可有口干、头晕、失眠、便秘、腹泻、皮疹、面部潮红。偶有白细胞减少，轻度转氨酶增高等。
 
【禁忌症】
对本品过敏者、严重肾功能不全及孕妇、哺乳期妇女禁用。
肝、肾功能不全者及婴幼儿慎用，注意应排除胃癌后才能使用本品。

注：以下产品不同规格和不同价格，购买时请以电话咨询为准！
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原产地英文商品名:
FAMOTIDINE(PEPCID GENERIC) 20mg/tablet 100tablets/bottle
原产地英文药品名:
FAMOTIDINE
中文参考商品译名:
法莫替丁(PEPCID仿制药) 20毫克/片 100片/瓶
中文参考药品译名:
法莫替丁
产地：美国
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原产地英文商品名:
FAMOTIDINE 20mg/tablet 100tablets/bottle
原产地英文药品名:
FAMOTIDINE
中文参考商品译名:
法莫替丁 20毫克/片 100片/瓶
中文参考药品译名:
法莫替丁
生产厂家中文参考译名:
HOVID（香港 ）
生产厂家英文名:
HOVID
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Famotidine
Generic Name: famotidine (fam OH ti deen)
Brand names: Heartburn Relief, Leader Acid Reducer, Mylanta AR, Pepcid, Pepcid AC, Pepcid AC Maximum Strength, Pepcid RPD
What is famotidine?
Famotidine is in a group of drugs called histamine-2 blockers. It works by decreasing the amount of acid the stomach produces.
Famotidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Famotidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.
Famotidine may also be used for other purposes not listed in this medication guide.
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Important information about famotidine
You should not use this medication if you are allergic to famotidine or similar medications such as ranitidine (Zantac), cimetidine (Tagamet), or nizatidine (Axid).
Before taking famotidine, tell your doctor if you have kidney or liver disease, stomach cancer or other problems, or asthma, COPD, or other breathing problems.
Avoid taking cimetidine (Tagamet), ranitidine (Zantac), or nizatidine (Axid) while you are taking famotidine, unless your doctor has told you to.
Famotidine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Famotidine may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor's instructions very closely.
Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.
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Before taking famotidine
Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.
You should not use this medication if you are allergic to famotidine or similar medications such as ranitidine (Zantac), cimetidine (Tagamet), or nizatidine (Axid).
Ask a doctor or pharmacist if it is safe for you to take famotidine if you have:
kidney disease; or
liver disease;
stomach cancer or other problems; or
asthma, chronic obstructive pulmonary disease (COPD), or other breathing problems.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Famotidine can pass into breast milk and may harm a nursing baby. Do not use famotidine without telling your doctor if you are breast-feeding a baby
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How should I take famotidine?
Use famotidine exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow your doctor's instructions.
The chewable tablet must be chewed thoroughly before swallowing.
Shake the oral suspension (liquid) for 5 to 10 seconds before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Although most ulcers heal within 4 weeks of famotidine treatment, it may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
Famotidine may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor's instructions very closely.
Store famotidine at room temperature away from moisture, heat, and light. Throw away any unused famotidine liquid that is older than 30 days
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What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
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What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, stomach pain, fast heart rate, or fainting.
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What should I avoid while taking famotidine?
Avoid drinking alcohol. It can increase the risk of damage to your stomach.
Avoid taking cimetidine (Tagamet), ranitidine (Zantac), or nizatidine (Axid) while you are taking famotidine, unless your doctor has told you to.
Famotidine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert
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Famotidine side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using famotidine and call your doctor at once if you have a serious side effect such as:
easy bruising or bleeding;
fast or pounding heartbeat;
confusion, hallucinations, seizure;
numbness or tingly feeling; or
jaundice (yellowing of the skin or eyes).
Less serious famotidine side effects may include:
nausea, vomiting, diarrhea, constipation;
dry mouth;
dizziness, weakness, mood changes;
headache; or
muscle cramps, joint pain.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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What other drugs will affect famotidine?
Tell your doctor about all other medications you use, especially:
atazanavir (Reyataz);
itraconazole (Sporanox);
ketoconazole (Nizoral); or
aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), piroxicam (Feldene), and others.
This list is not complete and there may be other drugs that can interact with famotidine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
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Where can I get more information?
Your pharmacist can provide more information about famotidine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use famotidine only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.