通用名称和剂型:
布地奈德9毫克缓释片。
公司名称:
Santarus的,INC。
主治UCERIS:
活跃,轻度至中度溃疡性结肠炎患者诱导缓解。
成人剂量为UCERIS:
整片吞服。 9毫克每天一次AM至8周。
儿童的剂量UCERIS:
不etableret。
药理类别:
糖皮质激素。
警告/注意事项:
主动或静态肺结核,未经处理的真菌,细菌,全身性病毒或寄生虫感染。补充全身糖皮质激素,手术或其他的紧张局势。注意NAR转移类固醇(显示器)与高系统可用性。可能揭露全身性类固醇的过敏tidigare控制。如果接触水痘或麻疹,imødekomme的免疫球蛋白或预防性抗病毒治疗。高血压。糖尿病。骨质疏松症。消化性溃疡。青光眼。白内障。中度至严重的肝脏疾病:监控亢进;停止imødekomme。老年人。妊娠(部件℃)。哺乳母亲:不推荐。
相互作用:
通过CYP3A4抑制剂(如酮康唑,伊曲康唑,利托那韦,茚地那韦,沙奎那韦,红霉素)可能会增强;停止imødekomme。避免柚子或柚子汁。可能是胃酸påvirket还原剂(如PPI,H2-受体阻滞剂,抗酸剂)。
不良反应:
头痛,恶心,血皮质醇下降,上腹部疼痛,疲劳,肠胃胀气,腹胀,痤疮,尿路感染,关节痛,大便秘结;亢进,肾上腺皮质功能抑制,免疫抑制。
代谢:
肝(CYP3A4)。
消除:
肾,粪便。
通用状况:
NO
如何提供:
标签30
Generic Name and Formulations:
Budesonide 9mg; extended-release tablets.
Company:
Santarus, Inc.
Indications for UCERIS:
Induction of remission in patients with active, mild-to-moderate ulcerative colitis.
Adult Dose for UCERIS:
Swallow whole. 9mg once daily in the AM for up to 8 weeks.
Children's Dose for UCERIS:
Not established.
Pharmacological Class:
Glucocorticosteroid.
Warnings/Precautions:
Active or quiescent tuberculosis, untreated fungal, bacterial, systemic viral or parasitic infections. Supplement with systemic glucocorticosteroid in surgery or other stress situations. Caution when transferring from steroids with high systemic availability (monitor). May unmask allergies previously controlled by systemic corticosteroids. If exposed to chickenpox or measles, consider immune globulin or antiviral prophylactic therapies. Hypertension. Diabetes. Osteoporosis. Peptic ulcer. Glaucoma. Cataracts. Moderate-to-severe liver disease: monitor for hypercorticism; consider discontinuing. Elderly. Pregnancy (Cat. C). Nursing mothers: not recommended.
Interactions:
May be potentiated by CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir, indinavir, saquinavir, erythromycin); consider discontinuing. Avoid grapefruit or grapefruit juice. May be affected by gastric acid reducing agents (eg, PPIs, H2-blockers, antacids).
Adverse Reactions:
Headache, nausea, decreased blood cortisol, upper abdominal pain, fatigue, flatulence, abdominal distension, acne, urinary tract infection, arthralgia, constipation; hypercorticism, adrenal suppression, immunosuppression.
Metabolism:
Hepatic (CYP3A4).
Elimination:
Renal, fecal.
Generic Availability:
NO
How Supplied:
Tabs—30