部份中文法莫替丁处方资料（仅供参考） 【中文品名】法莫替丁 【药效类别】抗消化性溃疡病药>H2受体阻滞药类 【通用药名】FAMOTIDINE 【别　　名】ガスタ一, Famodil, Foxadul, Ganor, Gaster, Gastridine, Pepcid, Pepcidine, MK-208, Pepdul 【化学名称】 N-[1-Amino-3-[[2-(diaminomethyleneamino)-1,3-thiazol-4-yl]methylsulfanyl]propylidene]sulfamide 【CA登记号】[76824-35-6] 【结 构 式】 【分 子 式】C8H15N7O2S3 【分 子 量】337.45 【收录药典】JP14 【开发单位】山之内制药株式会社 (日本) 【首次上市】1985年，日本 【性　　状】类白色或微黄色结晶性粉末，无臭，味微苦，水溶液呈弱碱性。易溶于稀乙酸，极微溶于水、乙醇，几乎不溶于氯仿、乙醚。mp163~164℃。 【用　　途】抗溃疡药。可拮抗胃粘膜细胞的组胺H2受体而显示出强效而持久的胃酸分泌抑制作用。口服用于治疗胃溃疡、十二指肠溃疡，吻合口溃疡、反流性食管炎。口服或静注用于治疗上消化道出血(由消化性溃疡、急性应激性溃疡、出血性胃类所致)及卓-艾二氏综合征。本品具有安全范围(LD50/ED50)广，无抗雄激素作用和抑制药物代谢酶作用等特点。 【用法用量】 口服，一次20mg（一次1片），一日2次，早、晚餐后或睡前服。4～6周为一疗程。 溃疡愈合后的维持量减半。 【不良反应】少数患者可有口干、头晕、失眠、便秘、腹泻、皮疹、面部潮红、白细胞减少。偶有轻度一过性转氨酶增高等。 【禁    忌】对本品过敏者、严重肾功能不全者禁用。 【注意事项】应排除胃癌后才能使用。肝肾功能不全者慎用。 【孕妇及哺乳期妇女用药】孕妇、哺乳期妇女禁用。 【儿童用药】婴幼儿慎用。 【药物相互作用】本品不与肝脏细胞色素P450酶作用，故不影响茶碱、苯妥英、华法林及地西泮等药物的代谢，也不影响普鲁卡因胺等的体内分布。但丙磺舒会抑制法莫替丁从肾小管的排 泄。 【生产厂家】安斯泰来 包装规格 D錠10mg： 100錠（10錠×10） 140錠（14錠×10） 500錠（10錠×50） 500錠（バラ） 560錠（14錠×40） 1,000錠（10錠×100） D錠20mg： 100錠（10錠×10） 140錠（14錠×10） 500錠（10錠×50） 500錠（バラ） 560錠（14錠×40） 1,000錠（10錠×100 www.oneyao.net http://www.info.pmda.go.jp/go/pack/2325003F3035_1_13/ ----------------------------------------------- Gaster D Tablets 10mg（ガスターD錠10mg Brand name : Gaster D Tablets 10mg 　Active ingredient: Famotidine 　Dosage form: white tablet (φ: 7.5mm, thickness: 3.5mm) 　Print on wrapping: (Face) house-mark + 120, 10mg, (Back) ガスターD, 10mg ----------------------------------------------- Gaster D Tablets 20mg（ガスターD錠20mg） Brand name : Gaster D Tablets 20mg 　Active ingredient: Famotidine 　Dosage form: white tablet (φ: 8.5mm, thickness: 3.6mm) 　Print on wrapping: (Face) house-mark + 121, 20mg, (Back) ガスターD, 20mg ----------------------------------------------- Effects of this medicine This medicine blocks the histamine 2 receptors of the gastric mucosa, thus suppress the secretion of the stomach acid. It is usually used in the treatment of gastric ulcer, duodenal ulcer, gastritis and esophagitis. Before using this medicine, be sure to tell your doctor and pharmacist •If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. •If you are pregnant or breastfeeding. •If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.) Dosing schedule (How to take this medicine) •Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>> •For the treatment of gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastrointestinal hemorrhage, reflux esophagitis, and Zollinger-Ellison syndrome: In general, for adults, take 2 tablets (20mg of the active ingredient) at a time, twice daily (after breakfast, and after supper or before going to bed). You may also take 4 tablets (40mg) at a time, once daily (before going to bed). For the treatment of gastric mucosal lesions associated with acute gastritis and acute exacerbation of chronic gastritis: In general, for adults, take 1 tablet (10mg) at a time, twice daily (after breakfast, and after supper or before going to bed). You may also take 2 tablets (20mg) at a time, once daily (before going to bed). The dosage may be adjusted according to your disease, age or symptoms. In any case, strictly follow the instructions. •If you miss a dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time. •If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist. •Do not stop taking this medicine unless your doctor instructs you to do so. Precautions while taking this medicine • Possible adverse reactions to this medicine The most commonly reported adverse reactions include palpitation, rash/eruption, urticaria, facial oedema, constipation, irregular menstruation, gynaecomastia, etc. If any of these symptoms occur, consult with your doctor or pharmacist. The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. •facial pallor, cold sweat, dizziness on standing up  [shock, anaphylaxis] •sore throat, headache, muscle pain, symptoms of anemia, bleeding tendency  [aplastic anemia, pancytopenia, agranulocytosis, hemolytic anemia, thrombocytopenia] •fever, loss of appetite, red rash  [mucocutaneo-ocular syndrome, toxic epidermal necrolysis] •general malaise, loss of appetite, yellowing of the skin and the whites of the eye  [hepatic function disorder, jaundice] •muscle pain, feelings of weakness, brown urine  [rhabdomyolysis] The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. Storage conditions and other information •Keep out of the reach of infants and children. Store away from direct sunlight, heat and humidity. •Discard the remainder. Do not store them.