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当前位置:药品说明书与价格首页 >> 皮肤性病 >> 尖锐湿疣 >> 尖锐湿疣药品目录 >> 慷定来,普达非洛乙醇溶液|Condylox(Podofilox Solution)

慷定来,普达非洛乙醇溶液|Condylox(Podofilox Solution)

2012-01-26 16:30:01  作者:新特药房  来源:中国新特药网天津分站  浏览次数:1216  文字大小:【】【】【
简介: 英文药名: Condylox(Podofilox Solution) 中文药名: 普达非洛乙醇溶液, 慷定来 生产厂家: 这个药通常也叫: Condyline 药品简介 Podofilox (Condylox) – 纯化的 podophyllotoxin, 【药品名称】 ...

英文药名: Condylox(Podofilox Solution)

中文药名: 普达非洛乙醇溶液, 慷定来

生产厂家:

这个药通常也叫: Condyline

药品简介

Podofilox (Condylox) – 纯化的 podophyllotoxin,
【药品名称】
通用名:鬼臼毒素溶液
商品名:慷定来(Condylox®)
英文名:Podophyllotoxin Solution
本品主要成分为鬼臼毒素,其化学名称为:[5R-(5α,5αβ,8aα,9α)],5,8,8α,9-四氢-9-羟-5-(3,4,5-三甲氧苯基)呋喃(3,,4, :6,7)萘并-[2,3-d]-1,3-间二氧杂环烯-6-(5αH)-酮
其结构式:
分子式:C22H22O8
分子量:414.40

【性状】
本品为无色澄明溶液,有醇味。

【药理毒理】
鬼臼毒素是植物鬼臼树脂中的有效成分。它能抑制细胞分裂并具有抗肿瘤和抗炎的作用。鬼臼毒素外用时仅微量被人体吸收,按推荐的使用方法和剂量,不会产生全身效应。

【药代动力学】
本品0.01~0.05毫升连续使用3天,患者血清中未检测出鬼臼毒素。0.1毫升使用于4CM2以上表面时,1~2小时后血药浓度小于5ng/ml,4小时后血药浓度小于3ng/ml。0.1~1.5毫升用于大面积治疗时,1~12小时后血药峰浓度为1~17ng/ml。治疗尖锐湿疣时用药剂量很少超过0.1毫升。鬼臼毒素无体内蓄积。

【适应症】
男女外生殖器尖锐湿疣

【用法用量】
患者可自行用本品外用治疗尖锐湿疣,但尖锐湿疣极多且一次用量超过0.5毫升的患者应该在医生指导下进行治疗。使用前应先用肥皂和水清洗患部,干燥后用棉签蘸药液轻搽于疣体上。棉签只能一次性使用。避免药液接触周围皮肤和粘膜。搽抹药液后应该让患部干燥几分钟,无需洗净。每次治疗后应该把手洗干净。
本品不能用于治疗其他疣症。
如无其他医嘱,请严格遵照以下剂量用药:
每日使用本品2次(间隔12小时)连续3天,随后停药4天,应重复使用本品治疗直至疣体消失,最多应用5周。若使用5个疗程(即5周)后仍无效,应该改用其他方法治疗。

【不良反应】
可见用药部位的局部炎症,如瘙痒、烧灼感、粘连性炎症、龟头、包皮炎症及溃疡。

【禁忌症】
本品禁用于对鬼臼毒素过敏者,孕妇及哺乳期妇女及12岁以下儿童。

【注意事项】
本品仅用于治疗尖锐湿疣,不能用于其他疣症和痣的治疗。
本品不得与眼睛接触。若不慎进入眼内,应立即用水冲洗并求医救治。
治疗期应该避免过量饮酒。
男性患者在尖锐湿疣完全治疗前应使用避孕套。
应建议患者的性伴侣去医院作有关检查。
若发现有任何副作用或怀孕应告之医生。
注意药物有效期。
妥善保管药物,避免孩童拿取。

【孕妇及哺乳期妇女】
孕妇及哺乳期妇女禁用本品。

【儿童用药】
儿童禁用本品。

【老年患者用药】
尚无相关资料。

【药物相互作用】
因含鬼臼毒素,故本品应避免与其他含鬼臼树脂制剂同时使用。

【药物过量】
暂无药物过量的资料。应严格按照说明书推荐方法使用。

【规格】
3.5ml

Podofilox (Condylox) genital warts treatment solutions
Podofilox (Condylox) is one of most commonly prescribed patient-applied genital wart treatment solution. This drug is antimitotic. It’s available in a new 0.5% concentration option, it should be applied to genital warts twice a day for exactly 3 days, then 4th day is off. Carry on doing these 4 days cycles for around 3 times .
Right after those 3 cycles, you have to figure out whether this treatment has any positive effect, in other words “Does it work for you?”. Consult your doctor whether you have to carry on with this this therapy.
Side effects are quite common thing when doing Podofilox therapy. Quite a few patients use to report skin irritation & burning, pain, as well as problems with the skin in the area where the substance had been utilized.
To avoid those nasty side effects you should spread the treatment carefully throughout the infected areas and don’t put too much of the substance. Don’t apply this medicine on the non-infected areas! In the event of follow-up therapies these side effect symptoms will either become less severe or will disappear at all.
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Important note
HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Monograph title
PODOFILOX - TOPICAL SOLUTION
Phonetic pronunciation
(poh-DOFF-ih-lox)
Common brand name(s)
Condylox
Uses
Podofilox solution is used to treat warts on the outside of the genitals. It stops the growth of the wart and the wart eventually falls off. Podofilox belongs to a group of drugs called antimitotics.
Other uses
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used to treat a skin infection called molluscum contagiosum.
How to use
Read the Patient Information Leaflet available from your pharmacist before you start using podofilox solution and each time you get a refill. If you have any questions, ask your doctor or pharmacist.This medication is for use on the skin only. Only apply this medication to the genital warts that your doctor has identified for you. Do not use this medication on warts around the anus or on the mucous membranes (such as in the urethra, rectum, and vagina), inside your body, or on any other skin growths.Use this medication usually twice daily (once in the morning and once in the evening, every 12 hours), for 3 days in a row, followed by no treatment for the next 4 days. If the warts do not go away, you may repeat this 7-day cycle up to a total of 4 treatment weeks in a row. Follow your doctor's directions exactly.First wash the area to be treated with soap and water, and dry thoroughly. Use an applicator that comes with this product, dip it into the solution just enough to wet it, but not so much that solution is dripping from the tip. Apply this medication only to the warts your doctor has directed you to treat. Do not apply it to the area surrounding the warts. It may help to use a hand mirror.For warts within skin folds, pull the skin fold open and apply the medication. Let the medication dry before allowing the skin folds around the warts to return to their normal position.Only use the applicator once. Do not dip it into the solution again. Throw it away in a safe place after use. Wash your hands with soap and water after each application.Do not cover the treated area with bandages or other waterproof dressings. Covering the area with cotton gauze, or cotton underwear for the genital area, is permitted.Use this medication regularly to get the most benefit from it. To help you remember, use a calendar to mark the days you will be applying the medication each week.Avoid getting this medication in the eyes/nose/mouth, on healthy skin, or on other areas as mentioned above. If the medication gets on healthy skin, wipe it off immediately and wash the area thoroughly with soap and water and rinse off. If the medication gets in your eyes, nose, or mouth, flush the area with plenty of water for 15 minutes and contact your doctor.Do not apply a large amount of this medication or apply it to a large area. Ask your doctor or pharmacist for details. Do not use it more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.Tell your doctor if your condition persists after 4 weeks of treatment, or if it worsens, or if new growths appear during treatment. Genital warts often return after treatment.
Missed dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Precautions
Before using podofilox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: injured/irritated/inflamed skin around the treated area, recent surgery on the treated area.This medication is not a cure for genital warts. These warts are caused by a virus called human papillomavirus (HPV). Podofilox does not destroy the virus. It only helps to remove the warts, but new warts may form or old warts may return, during and after treatment.Do not have sexual intercourse on the days you have applied this medication.Genital warts are spread by sexual contact. Condoms (such as latex or polyurethane types) may help prevent the spread of genital warts to your partner. Consult your doctor or pharmacist for more details.This medication must not be used during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control with your doctor. If you become pregnant or think you may be pregnant, tell your doctor immediately.It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Side effects
Redness, itching, burning, and pain may occur in the treated area. If any of these effects persist or worsen, or if you have bleeding, severe swelling, or severe pain, wash the medication off with soap and water. Stop using this medication and tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Drug interactions
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.Keep a list of all the products you use. Share the list with your doctor and pharmacist to reduce your risk for serious medication problems.
Overdose
This product may be harmful if too much of it is applied to the skin or if it is swallowed. If overdose or swallowing is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. If too much of this medication is applied to the skin, wash it off with plenty of soap and water. Symptoms of overdose may include: nausea, vomiting, diarrhea, fever, coma, trouble breathing, seizures.
Notes
Do not share this medication with others.Keep all medical appointments.
Storage
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from high heat and open flame. Do not freeze. Keep the container cap tightly closed. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
New search
Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First DataBank, Inc., 2011. This copyrighted material has been downloaded from a licensed data provider.

The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment.

责任编辑:admin


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