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当前位置:药品说明书与价格首页 >> 激素类 >> 药品目录 >> 甲状腺激素及抗甲状腺药类 >> 注射用普罗瑞林|HIRTONIN(protirelin tartrate)

注射用普罗瑞林|HIRTONIN(protirelin tartrate)

2012-02-05 20:25:55  作者:新特药房  来源:互联网  浏览次数:207  文字大小:【】【】【
简介:【中文品名】酒石酸普罗瑞林【药效类别】诊断用药>促甲状腺素释放激素类【通用药名】PROTIRELIN TARTRATE【别  名】Abbott-38579, Antepan, Relefact-TRH, Stimu-TSH, Thypinone, Thyrefact, Tiregan, TRH Pr ...

【中文品名】酒石酸普罗瑞林
【药效类别】诊断用药>促甲状腺素释放激素类
【通用药名】PROTIRELIN TARTRATE
【别  名】Abbott-38579, Antepan, Relefact-TRH, Stimu-TSH, Thypinone, Thyrefact, Tiregan, TRH Prem, TRH-Roche
【化学名称】 L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, monotartrate, monohydrate
【CA登记号】[]
【结 构 式】

【分 子 式】C16H22N6O4﹒C4H6O6﹒H2O
【分 子 量】530.49
【收录药典】JP14
【开发单位】Abbott, HMR
【首次上市】法国
【性  状】
【用  途】
一种合成的促甲状腺素释放激素,作为诊断用药。

成分:Protirelin酒石酸0.732 mg(作为protirelin0.5毫克)

说明:Probrin是一种激素(促甲状腺激素释放激素),在中枢神经系统的各个部分,如海马,局部形成一个网状神经调节类似物。它产生兴奋作用和兴奋剂的行动,Protirelin拮抗内源性阿片类药物也酒石酸从而提高脊髓损伤后脊髓血流量。

适应症:

头部外伤后扰动意识

连续意识障碍蛛网膜下腔出血

脊髓损伤

用法用量:静脉注射,Probrin是重组,生理盐水,葡萄糖水或蒸馏水5-10毫升注射并以非常缓慢的速度进行管理。头部外伤后扰动意识:101-4安瓿静脉注射单或静脉滴注天。连续意识障碍蛛网膜下腔出血:4单次静脉注射或静脉滴注针剂。治疗应继续取决于该条件的严重程度。脊髓损伤:101-4安瓿静脉注射单或静脉滴注天。

如何提供:包一ml安瓿含有酒石酸Protirelin0.732 mg(作为protirelin0.5毫克)

[附件:/uploadfile/article/uploadfile/201012/20101226085652833.pdf]

Composition: Protirelin tartrate 0.732 mg (as protirelin 0.5 mg)

Description: Probrin is an analogue of TRH (Thyrotropin Releasing Hormone), a neuromodulator localized in various parts of central nervous system such as hippocampus and reticular formation. It produces arousal effect and analeptic action, Protirelin tartrate also antagonizes endogenous opioids thus improves spinal cord blood flow after spinal cord injury.

Indications:

  • Disturbance of consciousness after head trauma

  • Continuous disturbance of consciousness after subarachnoid hemorrhage

  • Spinal cord injury

Dosage: For intravenous injection, Probrin is reconstituted with 5-10 ml of physiological saline, glucose or distilled water for injection and administered at a very slow rate. Disturbance of consciousness after head trauma: 1-4 ampoules daily for 10 days by single intravenous injection or intravenous drip infusion. Continuous disturbance of consciousness after subarachnoid hemorrhage: 4 ampoules by single intravenous injection or intravenous drip infusion. Treatment should be continued depending upon the severity of the condition. Spinal cord injury: 1-4 ampoules daily for 10 days by single intravenous injection or intravenous drip infusion.

How supplied: Pack of one ml ampoule containing Protirelin tartrate 0.732 mg (as protirelin 0.5 mg)

责任编辑:admin


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