英文药名: Aristospan(Triamcinolone Hexacetonide Vial)

中文药名: 曲安西龙注射液

药品说明

药品名称

曲安西龙,去炎松，氟羟氢化泼尼松，氟羟强的松龙

英文名
Triamcinolone,Fluoxyprednisolone，Triamcortisone，ADCORTYL，ARISTOCORT，LEDERCORT

药理及应用
抗炎作用较氢化可的松、泼尼松均强。水钠潴留作用则较稍微。口服易吸收。适用于类风湿性关节炎、其它结缔组织疾病、支气管哮喘、过敏性皮炎、神经性皮炎、湿疹等，尤适用于对皮质激素禁忌的伴有高血压或浮肿的关节炎。仅用于口服。其双醋酸酯除口服外，尚可采用肌注、皮下注射或关节腔内注射，以缓解局部炎症。注射作用缓慢而持久，一般可维持疗效达2～3周以上。

用法用量
（1）口服: 开始时1次4mg，1日2～4次。维持量为1次1～4mg，1日1～2次，通常1日不超过8mg。如为其双醋酸酯，1日量10～20mg，3～4次分服。2～3日后逐渐酌减用量。
（2）肌注：每1～4周1次40～80mg。
（3）皮下注射:　1次5～20mg。
（4）关节腔内注射:　每1～7周1次5～40mg。

注重事项
（1）可引起厌食、眩晕、头痛、嗜眠等，但一般不至引起浮肿、高血压、满月脸等反应。
（2）长期使用或用量较大时可致胃溃疡，血糖升高、骨质疏松、肌肉萎缩、肾上腺功能减退以及诱发感染等，结核病、消化性溃疡、糖尿病等患者及孕妇慎用。

规格：20mg/1ml 5支 x 1ml  

Generic Name: triamcinolone hexacetonide
Dosage Form: injection, suspension
Aristospan®
(Triamcinolone Hexacetonide Injectable Suspension, USP)
5 mg/mL PARENTERAL
NOT FOR USE IN NEWBORNS

FOR INTRALESIONAL ADMINISTRATION

NOT FOR INTRAVENOUS USE

What is Aristospan Injection (Triamcinolone)?
Triamcinolone injection is a steroid. It prevents the release of substances in the body that cause inflammation.

Triamcinolone injection is injected into the joint space to treat inflammation of the joints or tendons to treat arthritis, bursitis, or epicondylitis (tennis elbow). It is usually given in these conditions only as a short-term treatment of a severe or aggravated episode.

Triamcinolone injection is injected into soft tissues of the body to treat certain skin disorders caused by autoimmune conditions such as lupus, psoriasis, lichen planus, and others.

Triamcinolone injection may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Aristospan Injection (Triamcinolone)?
You should not receive this medication if you are allergic to triamcinolone, or if you have a condition called idiopathic thrombocytopenic purpura (ITP):

Before receiving triamcinolone injection, tell your doctor if you are allergic to any drugs, or if you have any type of infection (including tuberculosis), a thyroid disorder, a muscle disorder, stomach or intestinal problems, or if you have recently had a heart attack.

Long-term use of steroids can also cause harmful effects on your eyes. Your doctor may want you to have regular eye exams while you are receiving triamcinolone injection.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Steroids can lower the blood cells that help your body fight infections, making it easier for you to get sick from being around others who are ill, or from bacteria in a skin wound. Use caution to prevent illness, infection, or injury.

Do not receive a “live” vaccine while you are being treated with triamcinolone injection. The live vaccine may not work as well during this time, and may not fully protect you from disease.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroids.

There are many other medicines that can cause serious medical problems if you take them together with triamcinolone injection. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my healthcare provider before taking Aristospan Injection (Triamcinolone)?
You should not receive this medication if you are allergic to triamcinolone, or if you have a condition called idiopathic thrombocytopenic purpura (ITP):

Before receiving triamcinolone injection, tell your doctor if you are allergic to any drugs, or if you have:

any type of bacterial, fungal, or viral infection (including tuberculosis)
a thyroid disorder
a muscle disorder such as myasthenia gravis
diverticulitis, stomach or intestinal ulcer, or recent stomach surgery; or
if you have recently had a heart attack
If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Triamcinolone can pass into breast milk and may harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

This medication can decrease bone formation, which could lead to osteoporosis, especially with long-term use. Talk with your doctor about your specific risk of bone loss while receiving triamcinolone injection.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Aristospan Injection Side Effects
What are the possible side effects of Aristospan Injection (Triamcinolone)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

fast, slow, or uneven heart rate
feeling short of breath, even with mild exertion
swelling, rapid weight gain
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
problems with your vision
eye swelling, redness, discomfort, or drainage (may be signs of infection)
severe depression, changes in mood or behavior
seizure (convulsions); or
muscle pain, tenderness, or weakness
Less serious side effects may include:

nausea, bloating, appetite changes
stomach or side pain
headache, sleep problems (insomnia)
acne, scaling, or other skin changes
a wound that is slow to heal
thinning hair
bruising or swelling
sweating more than usual; or
irregular menstrual periods
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Aristospan Injection Interactions
What other drugs affect Aristospan Injection (Triamcinolone)?
Before using this medication, tell your doctor if you are using any of the following drugs:

aminoglutethimide (Cytadren)
birth control pills or hormone replacement therapy
a blood thinner such as warfarin (Coumadin)
cyclosporine (Neoral, Gengraf, Sandimmune)
digoxin (digitalis, Lanoxin)
insulin or diabetes medications you take by mouth
isoniazid (used to treat tuberculosis)
rifampin (Rifadin, Rimactane)
seizure medication such as phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), carbamazepine (Carbatrol, Tegretol), and others,
antibiotics such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), and others; or
aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others
This list is not complete and there may be other drugs that can interact with triamcinolone injection. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Aristospan Injection (Triamcinolone)?
Do not receive a “live” vaccine while you are being treated with triamcinolone injection. The live vaccine may not work as well during this time, and may not fully protect you from disease.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroids.

Aristospan Injection Dosage
How should I take Aristospan Injection (Triamcinolone)?
Triamcinolone injection is given as an injection into a joint or soft tissue (such as a psoriasis lesion). Your doctor, nurse, or other healthcare provider will give you this injection. You will receive this injection in a clinic or hospital setting.

Steroids can lower the blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill, or from bacteria in a skin wound. Steroids can also slow the healing of skin wounds. Use caution to prevent illness, infection, or injury.

If you need to have any type of surgery, tell the surgeon ahead of time if you have recently received a triamcinolone injection injection.

Long-term use of steroids can cause harmful effects on the eyes, such as glaucoma or cataracts. If you receive triamcinolone injection for longer than 6 weeks, your doctor may want you to have regular eye exams.

Steroid medications should not be stopped suddenly. You may need to receive less and less before you are taken off the medication completely.

Your doctor may instruct you to limit your salt intake while you are receiving triamcinolone injection. You may also need to take potassium supplements. Follow your doctor’s instructions.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are being treated with triamcinolone injection.

What happens if I overdose on Aristospan Injection (Triamcinolone)?
Seek emergency medical attention if you think you have received too much of this medicine.

Since this medication is given by a healthcare professional, an acute overdose is unlikely to occur.

What happens if I miss a dose of Aristospan Injection (Triamcinolone)?
Call your doctor for instructions if you miss an appointment for your injection.

Edited from everydayhealth.com