英文药名: Brevicon 0.5mg/35mcg(Norethindrone/Ethinyl Estradiol Birth Control Pills)

中文药名: 炔诺酮炔雌醇避孕药

品牌药生产厂家: Pfizer

药品名称

【别名】 妇康;去甲脱氢羟孕酮;探亲避孕药;炔诺酮
生产厂家

Pfizer 辉瑞
药理作用

属19-去甲基睾酮类合成口服孕激素药物。有较强的孕激素活性和轻度的雄激素活性。
适应症

1.为口服避孕药。
2.用于治疗功能性子宫出血、妇女不育症、痛经、闭经、子宫内膜异位症、子宫内膜增生过度等。
用量用法

1.用作短效口服避孕药：包括复方炔诺酮片、膜或纸片以及口服避孕片（膜）０号，从月经周期第５日开始服药，每日１片，晚饭后服用为宜（上夜班者早饭后服），连服２２日，不能间断，服完等月经来后的第５日继续服药。
2.用作探亲避孕药：探亲避孕丸，于同居当晚开始服用，每晚１丸（５ｍｇ）同居１０日之内，必须连服１０丸；同居半个月，连服１４丸；超过半个月者，服完１４丸后接着改服短效口服避孕药，直至探亲期结束。
3.治疗功能性子宫出血：每８小时服１片炔诺酮片、膜或纸片（２．５ｍｇ）（紧急情况下每３小时服药１次，待流血明显减少后改为８小时１次），然后逐渐减量，直至维持量每日１次１片，再连服２０日；也可在流血停止后，每日加服炔雌醇０．０５ｍｇ或己烯雌酚１ｍｇ，共２０日。
4.不育症：口服炔诺酮２．５ｍｇ和炔雌醇０．０５ｍｇ，每日１次，连服２０日，共３个周期。
5.痛经、子宫内膜异位症：于月经第５－７日开始，每日口服１次２．５ｍｇ，连服２０日。
任何疑问，请遵医嘱！
规格

每片含炔诺酮０．5ｍｇ和炔雌醇０．０３５ｍｇ;
每片含炔诺酮1mg和炔雌醇０．０３５ｍｇ。
炔诺酮双相片（Ortho-Novum10／11）：开始10日，每片含炔诺酮0.5毫克和炔雌醇0.035毫克，继后11日，每片含相应药物1毫 克和0.035毫克。
注意事项

少数妇女可有恶心、呕吐、头昏、乏力、嗜睡等类早孕反应及不规则出血、闭经、乳房胀、皮疹等，一般可自行消失。
作为避孕药使用时应注意：
1.哺乳妇女服药后可能乳汁减少，故应于产后半年开始服用；人工流产者应来１次月经第５日开始用药。
2.漏服或迟服时避孕会失败，故必须每日定时服药；如漏服应在２４小时内补服１次。
3.服药期间可能发生突破性出血，可每日加服炔雌醇０．００５～０．０１５ｍｇ；一般会有经量减少、经期偏短现象，不必处理。
4.服药２２日后，一般过３～４日即来月经；如第７日仍未见月经，应开始服用下１个月的药。若连续发生２～３个月闭经，就予停药；也可考虑加服炔雌醇每日０．００５～０．０１ｍｇ。
5.肝病、肾炎、乳房肿块病人忌用。有子宫肌瘤、高血压及肝、肾病史者慎用。
6.服避孕药的吸烟妇女并发心血管疾病（中风、心肌梗塞等）较不吸烟者多，因此，服避孕药妇女应停止吸烟，或吸烟妇女（特别是年龄超过３５～４０岁者）不宜服避孕药。
禁忌

1. 严重的心血管疾病不宜使用；
2. 急、慢性肝炎或肾炎；
3. 血液病或血栓性疾病；
4. 内分泌疾病如需用胰岛素控制者、甲状腺功能亢进者；
5．恶性肿瘤、 癌前病变、子宫或乳房肿块者；
6．哺乳期（但可在医生的指导下使用只含孕激素的避孕药）；
7．原因不明的阴道异常出血；
8．精神病生活不能自理者；
9．吸烟者（特别是年龄超过35岁以上并且吸烟者）；
10. 怀孕中或可能怀孕的妇女；

Brevicon Description
This combination hormone medication is used to prevent pregnancy. It contains 2 hormones: a progestin and an estrogen. These hormones prevent pregnancy in 3 ways. One way is by preventing the release of an egg (ovulation). A second way is by changing the cervical mucus, making it more difficult for an egg to meet sperm (fertilization). A third way is by changing the womb lining, making it difficult for a fertilized egg to attach to the lining of the womb (implantation). A fertilized egg (embryo/unborn baby) needs to attach to the womb to receive blood and nutrients and continue to grow. If an embryo/unborn baby does not attach, it cannot survive.
Besides preventing pregnancy, birth control pills have been shown to help make your periods more regular, decrease blood loss and painful periods (dysmenorrhea), and decrease your risk of ovarian cysts.
Use of this medication does not protect you or your partner against sexually transmitted diseases (e.g., HIV, gonorrhea, chlamydia).

Brevicon Directions
Read the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill. The leaflet contains very important information on when to take your pills and what to do if you miss a dose. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth once daily or as directed by your doctor. Pick a time of day that is easy for you to remember, and take your pill at the same time each day.
It is very important to continue taking this medication exactly as prescribed by your doctor. With certain brands of birth control pills, the amount of estrogen and progestin in each active tablet will vary at different times in the cycle. Therefore, it is very important that you follow the package instructions to find the first tablet, start with the first tablet in the pack, and take them in the correct order. Do not skip any doses. Pregnancy is more likely if you miss pills, start a new pack late, or take your pill at a different time of the day than usual.
Taking this medication after your evening meal or at bedtime may help if you have stomach upset or nausea with the medication. You may choose to take this medication at another time of day that is easier for you to remember. No matter what dosing schedule you use, it is very important that you take this medication at the same time each day, 24 hours apart. Ask your doctor or pharmacist if you have any questions.
Your pill pack contains 21 pills with active medication. It may also contain 7 reminder pills with no medication. Take one active pill (with hormones) once daily for 21 days in a row. If you are using a product with 28 tablets, take an inactive pill once daily for 7 days in a row after you have taken the last active pill unless otherwise directed by your doctor. If you are using a product with 21 tablets, do not take any tablets for 7 days unless otherwise directed by your doctor. You should have your period during the fourth week of the cycle. After you have taken the last inactive tablet in the pack or gone 7 days without taking an active tablet, start a new pack the next day whether or not you have your period. If you do not get your period, consult your doctor.
If this is the first time you are using this medication and you are not switching from another form of hormonal birth control (e.g., patch, other birth control pills), take the first tablet in the pack on the first Sunday following the beginning of your menstrual period or on the first day of your period. If your period begins on a Sunday, begin taking this medication on that day. For the first cycle of use only, use an additional form of non-hormonal birth control (e.g., condoms, spermicide) for the first 7 days to prevent pregnancy until the medication has enough time to work. If you start on the first day of your period, you do not need to use back-up birth control the first week.
Ask your doctor or pharmacist for information about how to switch from other forms of hormonal birth control (e.g., patch, other birth control pills) to this product. If any of this information is unclear, consult the Patient Informatio

Brevicon Cautions
Before using this medication, tell your doctor or pharmacist if you are allergic to any estrogens (e.g., ethinyl estradiol, mestranol) or any progestins (e.g., norethindrone, desogestrel); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this product, consult your doctor or pharmacist if you have: history of stroke or other blood clots (e.g., in the legs, eyes, lungs), severe high blood pressure, abnormal breast exam, cancer (especially endometrial or breast cancer), diabetes that has caused kidney/eye/nerve/blood vessel disease, severe headaches, history of heart disease (e.g., heart attack, chest pain), heart valve disease, liver problems (e.g., liver tumor, active liver disease), current or suspected pregnancy, recent major surgery, long periods of sitting or lying down (e.g., immobility such as being bedridden), history of yellowing eyes/skin (jaundice) during pregnancy or while using hormonal birth control (e.g., pills, patch), unexplained vaginal bleeding, heavy tobacco use (especially if 35 or over).
Before using this product, tell your doctor your medical history, especially of: high blood pressure, high cholesterol or triglyceride (blood fat) levels, depression, diabetes, swelling (edema), gallbladder problems, kidney disease, migraine, obesity, irregular/missed/very light periods, recent pregnancy, thyroid problems.
Do not smoke cigarettes or use tobacco. Hormonal birth control (e.g., pills, injections, devices) combined with smoking significantly increases your risk for stroke, blood clots, high blood pressure, and heart attacks, especially in women older than 35. For more details, ask your doctor or pharmacist, or consult the Patient Information Leaflet that comes with this product.
If you have diabetes, this medication may make it harder to control your blood sugar levels. Monitor your blood sugar regularly as directed by your doctor. Tell your doctor the results and any symptoms such as increased thirst/urination. Your anti-diabetic medication or diet may need to be adjusted.
Notify your doctor beforehand if you will be having surgery or will be confined to a chair/bed for a long time (e.g., a long plane flight). You may need to stop the medication for a time or take special precautions.
This medication may cause blotchy, dark areas on your skin (melasma). Sunlight may worsen this effect. Avoid prolonged sun exposure, sunlamps, and tanning booths. Use a sunscreen, and wear protective clothing when outdoors.
If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur.
It may take longer for you to become pregnant after you stop taking birth control pills. Consult your doctor.
This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor immediately. If you have just given birth or had a pregnancy loss/abortion after the first 3 months, talk with your doctor about reliable forms of birth control, and find out when it is safe to start using birth control that contains a form of estrogen, such as this medication.
This medication passes into breast milk. This may affect milk production and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Brevicon Side Effects
Nausea, vomiting, headache, stomach cramping/bloating, dizziness, vaginal discomfort/irritation, increased vaginal fluids, or breast tenderness/enlargement may occur. Acne may improve or get worse. Vaginal bleeding between periods (spotting) or missed/irregular periods may occur, especially during the first few months of use. If any of these effects persist or worsen, notify your doctor promptly. If you miss 2 periods in a row (or 1 period if the pill has not been used properly), contact your doctor for a pregnancy test.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these serious side effects occur: changes in vaginal bleeding (e.g., continuous spotting, sudden heavy bleeding, missed periods), problem wearing contact lenses, dark patches on the skin (melasma), unwanted facial/body hair, swelling of the ankles/feet, weight changes (gain or loss).
This medication may rarely cause serious (sometimes fatal) problems from blood clots (e.g., pulmonary embolism, stroke, heart attack). Seek immediate medical attention if you experience: sudden shortness of breath, chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms/legs, headaches that are different from those you may have experienced in the past (e.g., headaches with other symptoms such as vision changes/lack of coordination, existing migraines becoming worse, sudden/very severe headaches), slurred speech, weakness on one side of the body, vision problems/changes.
Tell your doctor immediately if any of these rare but very serious side effects occur: lumps in the breast, severe stomach/abdominal/pelvic pain, mental/mood changes (e.g., depression, suicidal thoughts, persistent trouble sleeping), unusual tiredness, dark urine, yellowing eyes/skin.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.