英文商品名: APHTHASOL
英文药品名: AMLEXANOX
药品译名: 氨来呫诺
适应病症:
口腔溃疡
对于较弥漫性的口内溃疡，一般的药膏可能涂不胜涂，效果不佳。此时通常要合并抗过敏或类固醇类的口含片或口服药治疗。
口腔内会痛的溃疡和口腔癌较无关，不过也不是绝对的，最好要看专门的口腔内科。
更多医学专家一致推荐使用氨来占喏口腔贴片，促进溃疡愈合、止痛和预防作用
氨来占诺（Amlexanox）原为武田（Takeda）公司在日本开发上市的一种新型消炎抗过敏药物，后以许可证转让方式转让给美国Block Drug公司，该公司开发了用于治疗口腔溃疡的新适应症，于1996年12月13日5％氨来占诺糊剂被美国FDA批准作为口腔溃疡治疗药物上市，用于免疫系统正常的口腔溃疡患者的治疗，英文商品名为Aphthasol。2000年12月又在加拿大上市，商品名为Apthera，由阿塞斯公司生产。同时，阿塞斯制药从Block Drug公司获得许可开发新的后续产品，其氨来占诺生物降解聚合物圆片状制剂（商品名为Oradisc 2mg）正在美国和欧洲进行Ⅲ期临床试验，用于治疗口疮性溃疡，另一药物Orarinse为该公司正在开发的氨来占诺漱口液。
氨来占喏是唯一获FDA批准的口腔溃疡的治疗药物，国外临床前研究、临床试验及NDA尚无替代产品研究。
经临床证实，它是能够加速口腔溃疡治愈和消除疼痛的唯一药物，不仅有效的治疗而且可预防复发，是治疗口腔溃疡的一线药物。与国内已上市的同类药物比较，氨来占诺适应症十分明确，在口腔溃疡发病初期就能阻止溃疡发展，受到了广大口腔医生和患者的欢迎；该药疗效较好，起效快，用药3-5分钟左右止痛，溃疡1－2天愈合，能够显著的消炎止痛，促进口腔溃疡的愈合，特别是在溃疡初期，疗效更佳；与临床常用的肾上腺皮质类激素相比，治疗效果更好。
在剂型方面，采用口腔贴片可以克服药物被唾液稀释、生物利用度低的问题，因为它是利用药用高分子材料与口腔粘膜发生生物粘附的特性，易于给药，只需简单一贴，使药物定位于病灶部位, 即可黏附4小时以上持续发挥作用，贴片制剂移去即可终止给药，减轻口腔溃疡带来的持续疼痛；同时有效成分由粘膜吸收，避免药物的肝脏首过效应，提高生物利用度，副作用很小，安全可靠。
因此，把氨来占喏和双层贴片融合于一体，将是完美结合。贴片直接粘附于溃疡表面，可以保护溃疡面、消炎止痛、促进溃疡愈合。双层贴片由非粘附层(惰性层)和粘附层组成，氨来占喏包含在接触粘膜表面的粘附层中，而惰性层朝向口腔，药物单向释放到溃疡表面，有效防止药物进入唾液，提高了药物浓度和生物利用度；采用生物溶蚀性辅料，含药制剂可逐渐溶蚀直至完全消失（由于吞咽而进入消化道），使用方便。
Generic Name: amlexanox (topical) (am LEX a nox)
Brand Names: Aphthasol
INDICATIONS
Amlexanox oral paste, 5%, is indicated for the treatment of aphthIMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
AMLEXANOX - MUCOUS MEMBRANE
(am-LEX-a-nox)
COMMON BRAND NAME(S): Aphthasol

USES:
This medication is used to treat mouth (canker) sores. Canker sores usually heal on their own after 7 to 10 days. This medication helps the sore heal faster so that you can eat/speak more comfortably.
HOW TO USE:
Use this medication in the mouth only. Use it as soon as you notice a canker sore forming, usually 4 times daily or as directed by your doctor. Use this medication until the sore heals.
The best time to apply the medication is after brushing/flossing after meals and at bedtime. Wash your hands before applying the medication. Dry the canker sore by patting gently with a soft, clean cloth. Wet the tip of your index finger with a little water, and squeeze a pea-sized amount of the medication onto the fingertip. Gently dab the medication onto the sore. Repeat these steps if you have more than 1 canker sore. Wash your hands after using.
Do not to get the medication in the eyes. If you do get the medication in the eyes, flush with plenty of water.
Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day.
Tell your doctor/dentist if your condition worsens or does not improve greatly after 10 days.
SIDE EFFECTS:
Temporary pain, stinging, or burning at the application site may occur. If any of these effects persist or worsen, tell your doctor/dentist or pharmacist promptly.
Remember that your doctor/dentist has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor/dentist immediately if any of these unlikely but serious side effects occur: increased mouth sores, nausea, diarrhea.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.