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达泊西汀Priligy(Dapoxetine)

2012-10-27 23:50:41  作者:新特药房  来源:中国新特药网天津分站  浏览次数:941  文字大小:【】【】【
简介: Premature ejaculation occurs when a man ejaculates much sooner during sexual intercourse than either they or their sexual partner would like. While this is normal when it occurs sporadi ...

Premature ejaculation occurs when a man ejaculates much sooner during sexual intercourse than either they or their sexual partner would like. While this is normal when it occurs sporadically, it can be extremely problematic when it occurs on a regular basis. Premature ejaculation is relatively common and it has been estimated that nearly one out of three men will experience premature ejaculation at some point in their lives. While this can be embarrassing and stressful to deal with, treatments such as Priligy, or Dapoxetine, are extremely effective at treating premature ejaculation.
Causes of Premature Ejaculation
While it is very difficult to pinpoint one specific cause of premature ejaculation, it is believed that a combination of both psychological and biological factors are the main causes. Feelings of anxiety and interpersonal problems between the man and his sexual partner are just a few psychological issues that can cause premature ejaculation.
Biological factors such as irregular hormone levels, thyroid problems, irregular levels of chemicals within the brain and inflammation or infection of the urethra or prostate can also cause premature ejaculation. Additionally, feeling stressed, taking certain medications and having erectile dysfunction are further causes of premature ejaculation.
Treatment
When considering the various treatment options (like Kamagra for ED) that are available for premature ejaculation, Priligy is a promising treatment for men. While there are other drugs available for premature ejaculation, Priligy is the only medication that has received regulatory approval for the successful treatment of premature ejaculation.
Priligy or Dapoxetine, is a selective serotonin reuptake inhibitor, or SSRI, which are commonly prescribed for people suffering from depression. Since research has shown that SSRI’s are effective at delaying ejaculation, Priligy has become known as one of the most efficacious medications for premature ejaculation. This medication is an effective solution for premature ejaculation and it is relatively well-tolerated with minimal side effects.
Further research has shown that when men take Priligy 60 mg, it can significantly delay their ejaculation time and can allow them to enjoy a more satisfying sexual experience. When Priligy is taken three hours before engaging in sexual activity, it can greatly increase sexual performance by controlling ejaculation. In addition to deterring early ejaculation, Priligy can also allow men to feel more confident in their sexual abilities and increase confidence levels.


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部分中文 Priligy 处方信息(仅供参考)

通用名称:达泊西汀  
化学名称:(S)-N,N-二甲基-3-(萘基-1-氧基)-苯丙氨基盐酸盐,
英文名称:(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
用途:达泊西汀(dapoxetine)作为一种新型快速的SSRI,半衰期短,属于选择性5-羟色胺再吸收抑制剂(SSRI),用于治疗男性早泄和勃起功能障碍。
用法用量:每次60-100mg
特点:服用后由肠胃吸收,直接口服约20-30分钟起效; 作用时间持续数十天; 副作用小,检测不出,有轻微头痛、恶心等症状,但很快消失。
【药理作用】早泄是大脑性欲中心反应性过高所致,导致男性过早地射精。而大脑性欲中心存在5—羟色胺和多巴胺之类的化学物质,它们能传导强烈的射精冲动,而达泊西汀能干扰上述化学物质,达到延迟射精时间的目的。
【药代动力】本品口服吸收迅速,30~120min达血药峰值,1h内奏效。生物利用度约40%。食物能明显降低本品吸收速度、程度和作用的发生。本品在肝脏主要经CYP 3A4介导代谢为活性代谢物,约80%经粪便排泄,13%由尿排泄,在精液中排泄不到0.001%。母体药物和活性代谢物的半衰期均为2h。65岁以上老年男性、肝功能不全和肾功能严重损害病人,清除率降低。
【适应症】早泄,包括器质性早泄,心理性早泄,以及内分泌系统紊乱造成的早泄都有很好的疗效(由于长期早泄引起的勃起不坚,射精无力,射精无快感,勃起时间短).
【用法用量】房事前1小时口服,每次一粒,可不定日服用。  
达泊 西 汀 常见的不良反应为恶心、腹泻、头晕和头痛。在1期临床试验中,恶心发生率最高,在60mg组达20%,有10%的患者中断试验,头晕为6.2%,腹泻为6.8%。单剂量3omg和6omg的不良反应发生率分别为26.2%和40.5%,多剂量分别为45.2%和40.5%,腹泻、恶心和头晕的出现dl比dg常见,ds的不良反应发生率与单剂量相似,多数是轻中度的不良反应。没有发现心血管系统、肝脏和血液系统等严重不良事件。
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产地国家: 德国
原产地英文商品名:
Priligy 30mg x 3 pills
原产地英文药品名:
Dapoxetine
原产地英文化合物名称:
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
中文参考商品译名:
Priligy 30毫克/粒 3粒/盒
中文参考药品译名:
达泊西汀 
中文参考化合物名称:
(S)-N,N-二甲基-3-(萘基-1-氧基)-苯丙氨基盐酸盐
生产厂家中文参考译名:
强生的子公司
生产厂家英文名:
Janssen-Cilag
--------------------------------------------------------------
原产地英文商品名:
Priligy 60mg x 6 pills
原产地英文药品名:
Dapoxetine
原产地英文化合物名称:
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
中文参考商品译名:
Priligy 60毫克/粒 6粒/盒
中文参考药品译名:
达泊西汀 
中文参考化合物名称:
(S)-N,N-二甲基-3-(萘基-1-氧基)-苯丙氨基盐酸盐
生产厂家中文参考译名:
强生的子公司
生产厂家英文名:
Janssen-Cilag
-------------------------------------------------------------
原产地英文商品名:
Priligy 30mg x 6 pills
原产地英文药品名:
Dapoxetine
原产地英文化合物名称:
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
中文参考商品译名:
Priligy 30毫克/粒 6粒/盒
中文参考药品译名:
达泊西汀 
中文参考化合物名称:
(S)-N,N-二甲基-3-(萘基-1-氧基)-苯丙氨基盐酸盐
生产厂家中文参考译名:
强生的子公司
生产厂家英文名:
Janssen-Cilag
--------------------------------------------------------------
原产地英文商品名:
Priligy 60mg x 3 pills
原产地英文药品名:
Dapoxetine
原产地英文化合物名称:
(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride
中文参考商品译名:
Priligy 60毫克/粒 3粒/盒
中文参考药品译名:
达泊西汀 
中文参考化合物名称:
(S)-N,N-二甲基-3-(萘基-1-氧基)-苯丙氨基盐酸盐
生产厂家中文参考译名:
强生的子公司
生产厂家英文名:
Janssen-Cilag

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