英文药名: Priligy(Dapoxetine)
中文药名: 盐酸达泊西汀片(必利劲)
药品介绍
达泊西汀(dapoxetine)作为一种新型快速的SSRI,半衰期短,属于选择性5-羟色胺再吸收抑制剂(SSRI),用于治疗男性早泄和勃起功能障碍。 特点:服用后由肠胃吸收,直接口服约20-30分钟起效; 作用时间持续数十天; 副作用小,检测不出,有轻微头痛、恶心等症状,但很快消失。
【商品名】盐酸达泊西汀片 【通用名】盐酸达泊西汀片 【成份】盐酸达泊西汀 【英文名称】Dapoxetine hydrochloride 【分子式】C21H23NO.HCl
【药理毒理】 达泊西汀是一种选择性5—羟色胺再吸收抑制剂。早泄可能是大脑性欲中心反应性过高所致,导致男性过早地射精。而大脑性欲中心存在着5—羟色胺和多巴胺之类的化学物质,它们能传导强烈的射精冲动,而达泊西汀能干扰上述化学物质,达到延迟射精时间的目的。
【药代动力】 本延时药口服吸收迅速,30~120min达血药峰值,1h内奏效。生物利用度约40%。食物能明显降低本品吸收速度、程度和作用的发生。本品在肝脏主要经CYP3A4介导代谢为活性代谢物,约80%经粪便排泄,13%由尿排泄,在精液中排泄不到0.001%。母体药物和活性代谢物的半衰期均为2h。65岁以上老年男性、肝功能不全和肾功能严重损害病人,清除率降低。
【适应症】 治疗男性早泄和勃起功能障碍,98%以上的人会自然提高勃起质量、勃起次数、勃起硬度,延长勃起时间,增加男女性爱高潮。
【用法用量】 房事前20-30分钟口服,每次一粒,可不定日服用。空腹服用(尤其避免与高脂食物同服)效果更佳,使用前勿喝茶。(使用者在具有性刺激状态下使用效果才显著)。
【不良反应】 达泊西汀总有效率为98%。其副作用主要是轻度头痛、恶心,不过这些副作用都是暂时的,很快会消失。高血压、心脏病患者可服用。
【禁忌】少年、儿童及孕妇忌用,对本品过敏者禁用。
Priligy Dapoxetine hydrochloride is the first approved drug against premature ejaculation. There is no other way to help to control ejaculation in men. Priligy can be taken 30 minutes before intercourse and its effect last 3-4 hours.
Priligy works by regulating levels of serotonin in the brain. Serotonin is responsible for transferring information to nerve cells, including nerves concentrated in the penis, causing ejaculation. Priligy may delay the transmission of these signals and thus extend the duration ratio by 200% to 300%. Priligy is extremely well tolerated by the body, mild side effects are extremely rare.
You can safely buy Priligy online to treat premature ejaculation and enjoy more satisfying, longer lasting sex. Fill out the consultation on our website to complete the order. Your consultation will be assessed by one of our doctors who will evaluate your case and decide whether Priligy is the right treatment for you. The drug will then be prescribed for you and delivered the next day. What is Priligy? The active ingredient in Priligy is Dapoxetine hydrochloride, a compound belonging to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Dapoxetine hydrochloride was originally an antidepressant although some doctors prescribed it in the past as a treatment for premature ejaculation. In the case of Priligy, the goal was to create a similar drug, but only for the purpose of controlling this particular condition. What doses are available? Priligy Dapoxetine hydrochloride is available in strengths of 30mg and 60mg. Your doctor will initially prescribe the dose of 30 mg to evaluate its effectiveness. Your doctor may increase your dose to 60mg if Priligy 30mg dose did not produce the expected results but has been well tolerated by the body. Priligy Dapoxetine can be used up to 3 hours before sexual activity. Does the product cause any side effects? Priligy can cause some side effects, but they are mild and do not affect many people. Priligy has a short half-life, which greatly reduces the intensity of any side effects and workes safely and effectively. Some of the side-effects which may occur when taking Priligy include nausea, dizziness, headaches, diarrhoea, abdominal pains, bloating, and vomiting. Some patients have reported a feeling of nervousness, fear, excitement, restlessness and stupor, whilst others have reported difficulty in achieving or maintaining an erection. You may suffer from excessive sweating, constipation, difficulty sleeping, strange dreams, or constant fatigue and sleepiness. Some men have reported an increased nasal obstruction, elevated blood pressure, difficulty concentrating, tremor, shivering, reduced sex drive, ringing in the ears, foggy vision, and upset stomach or dry mouth. Less common side effects: These side effects are not very common and affect less than 1 man in 100. They include mood swings, feeling overly excited, scared, experiencing free or irregular heartbeats, accelerated heart rate, feelings of loss, disorientation or difficulty with logical thinking. Precautions when taking Priligy Never use more than one dose Dapoxetine Priligy a day. Never change the prescribed dose without consulting the doctor. We advise you not to combine Priligy with alcohol, as the drug can increase the effects of alcohol and you may suffer from dizziness, drowsiness and slowed reactions. Alcohol consumption after the Priligy can also lead to fainting.
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