部分中文AZACTAM处方资料（仅供参考） 药物名称：AZACTAM　 药物别名：氨曲南，噻肟单酰胺菌素，AZACTAM 英文名称：Aztreonam 说　明：注射用 AZACTAM 每瓶1g（效价）。内含精氨酸0.78g（稳定、助溶用）。 功能作用：抗菌谱主要包括革兰阴性菌，诸如大肠杆菌、克雷白杆菌、沙雷杆菌、奇异变形杆菌、吲哚阳性变形杆菌、枸橼酸杆菌、流感嗜血杆菌、绿脓杆菌及其他假单胞菌、某些肠杆菌属、淋球菌等。 与头孢他定、庆大霉素相比、对产气杆菌、阴沟肠杆菌的作用高于头孢他定，但低于庆大霉素；对绿脓杆菌的作用低于头孢他定、与庆大霉素相近；对于质粒传导的β-内酰胺酶，本品较第3代头孢菌素为稳定。 口服不吸收，肌注1g，1小时血浓度达峰值，约为46μg／ml，t1/2约1.8小时；静注1g，5分钟血药浓度约为125μg／ml，1小时约为49μg／ml，t1/2约1.6小时。 体内分布较广，在脓疱液、心包液、胸水、滑膜液、胆汁、骨组织、肾、肺、皮肤等部位有较高浓度；在前列腺、子宫肌肉、支气管分泌物中也有一定浓度、在脑脊液中浓度低。主要由尿排泄，在尿中原形药物的浓度甚高。在乳汁中的浓度甚低，为血药浓度的1％，平均0.3μg／ml，1日间母乳内总量约0.3mg。 主要用于敏感的革兰阴性留所致的感染、包括肺炎、胸膜炎、腹腔感染、胆道感染、骨和关节感染、皮肤和软组织炎症，尤适用于尿路感染，也用于败血症。由于本品有较好的耐酸性能，因此，当微生物对青霉素类、头孢菌素类、氨基糖苷类等药物不敏感时，应用本品常可有效。 用法用量：一般感染：3～4g／d，分2～3次给予。严重感染：1次2g，1日3～4次。无其他合并症的尿路感染：只需用1g，分成1～2次给予。肌注：药物每1g，加液3～4ml溶解。静注：药物每1g，加液10ml溶解，缓慢推注。静滴：药物1g，加液50ml以上溶解（浓度不超过2％），滴注时间20～60分。 注射时，下列药液可用作本品的溶解-稀释液：灭菌注射用水、等渗氯化钠注射液、林格液、乳酸钠林格液、5％～10％葡萄糖液、葡萄糖氯化钠注射液等。用于肌注时，还可用含苯甲醇的氯化钠注射液作溶剂。 注意事项： （1）本品与青霉素类之间不存在交叉过敏反应，但对于青霉素过敏者及过敏体质者仍须慎用。 （2）本品对肝脏毒性不大，但对肝功能已受损的病人应观察其动态变化。 （3）不良反应有皮肤症状、如皮疹、紫癜、瘙痒等（共约2％）；消化道症状，如腹泻、恶心、呕吐、味觉改变、黄疸以及药物性肝炎（共约2％）；局部刺激症状，如血栓性静脉炎。注射部位肿胀（共约2.4％）；其他尚有神经系统症状、阴道炎、口腔损害、乏力、眩晕、出血等。 Medication name Generic name: Aztreonam - Injection Pronunciation: (az-TREE-oh-nam) Brand name(s): Azactam Uses Aztreonam is used to treat a wide variety of bacterial infections. This medication is an antibiotic that works by stopping the growth of bacteria. How to use This medication is usually given by injection into a vein or a muscle as directed by your doctor. The dosage is based on your medical condition and response to therapy.If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals as directed.Continue to use aztreonam until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.Tell your doctor if your condition persists or worsens. Precautions Before using aztreonam, tell your doctor or pharmacist if you are allergic to it; or to penicillins, cephalosporins, or certain other antibiotics (e.g., imipenem, meropenem); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease.This drug may rarely make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.This medication passes into breast milk in small amounts. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding. Drug interactions Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: cefoxitin, imipenem, live bacterial vaccines.Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.Aztreonam may cause false positive results with some diabetic urine testing products (cupric sulfate-type). Consult your doctor or pharmacist for recommendations. Make sure laboratory personnel and your doctors know you use this drug. Side effects Diarrhea, nausea, vomiting, dizziness, headache, blurred vision, or redness/discomfort/pain/swelling at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: fast/irregular heartbeat, confusion, easy bruising/bleeding, ringing in the ears, seizures, chest pain, yellowing eyes or skin, dark urine, severe stomach/abdominal pain, persistent nausea or vomiting, unusual fatigue, persistent signs of infection (e.g., fever, sore throat).This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool..Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection), or a new type of bacterial infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Missed dose For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Notes Laboratory and/or medical tests may be performed to monitor your progress or check for side effects. Consult your doctor for more details. Storage Consult the product instructions and your pharmacist for storage details. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Photos by medication strength Click the "Photos" link to see sample photographs for a specific medication strength. Common strengths Azactam in iso-osmotic dextrose 1 gram/50 mL IV Piggy Back Azactam in iso-osmotic dextrose 2 gram/50 mL IV Piggy Back *The photos shown are samples only. Not all photos of the drug may be displayed. Your medication may look different. If you have questions, ask your pharmacist. Important note HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Information last revised September 2011. Copyright(c) 2011 First Databank, Inc. Intravenous Piggyback Aztreonam|Dextrose-Water| Septicemia due to Aerobacter Species|Septicemia due to Enterobacter Species|Septicemia due to Enterobacter Spp.|Escherichia Coli Septicemia|Escherichia Coli Sepsis|E. Coli Sepsis|Septicemia due to Pseudomonas Aeruginosa|Sepsis due to Pseudomonas Aeruginosa|Serratia Sepsis|Septicemia due to Serratia Spp.|Septicemia due to Klebsiella Pneumoniae|Sepsis due to Klebsiella Pneumoniae|Sepsis due to Proteus Species|Septicemia due to Proteus Species|Septicemia due to Proteus Spp.|Pneumonia due to Klebsiella Species|Pneumonia due to Klebsiella Spp.|Pneumonia due to Pseudomonas Aeruginosa|Infection of the Lungs due to Pseudomonas Aeruginosa|Pneumonia due to Haemophilus Influenzae|Pfeiffer's Bacillus Pneumonia|Influenza Bacillus Pneumonia|Hemophilus Influenzae Pneumonia|H. Influenzae Pneumonia|H. Flu Pneumonia|Pneumonia due to Escherichia Coli|Pneumonia due to E. Coli|E. Coli Pneumonia|Pneumonia due to Gram-Negative Organisms|Infection of the Lungs due to Serratia Species|Pneumonia due to Serratia Species|Pneumonia due to Serratia Spp.|Infection of the Lungs due to Enterobacter|Proteus Spp. Pneumonia|Pneumonia due to Proteus Species|Bronchitis due to Hemophilus Influenzae|Bronchitis due to Haemophilus Influenzae|Bronchitis due to H. Influenzae|Bronchitis due to H. Flu|Bronchitis due to Influenzae Bacillus|Bronchitis due to Pfeiffer's Bacillus|Bronchitis due to Enterobacter Cloacae|Bronchitis due to Aerobacter Cloacae|Bronchitis due to Bacterium Cloacae|Bronchitis due to Klebsiella Pneumoniae|Bronchitis due to Escherichia Coli|Bronchitis due to E. Coli|Bronchitis due to Pseudomonas Aeruginosa|Bronchitis due to Proteus Species|Bronchitis due to Serratia Species|Lower Respiratory Tract Infections|Peritonitis due to Escherichia Coli|Peritonitis due to Klebsiella Pneumoniae|Peritonitis due to Enterobacter|Peritonitis due to Aerobacter|Peritonitis due to Pseudomonas Aeruginosa|Peritonitis due to Citrobacter Species|Peritonitis due to Serratia Species|Peritonitis due to Serratia Spp.|Intra-Abdominal Infection|Urinary Tract Infection due to Enterobacter Cloacae|UTI due to Enterobacter Cloacae|Urinary Tract Infection due to Escherichia Coli|E. Coli UTI|Klebsiella UTI|Urinary Tract Infection due to Klebsiella Species|Urinary Tract Infection due to Proteus Species|UTI due to Proteus Species|Urinary Tract Infection due to Pseudomonas Aeruginosa|UTI due to Pseudomonas Aeruginosa|Urinary Tract Infection due to Citrobacter Species|UTI due to Citrobacter Species|Urinary Tract Infection due to Serratia Species|UTI due to Serratia Species|Pelvic Inflammatory Disease due to Escherichia Coli|Pelvic Inflammatory Disease due to E. Coli|PID due to Escherichia Coli|Pelvic Inflammatory Disease due to Enterobacter Species|PID due to Enterobacter Species|Pelvic Inflammatory Disease due to Aerobacter Species|Pelvic Inflammatory Disease due to Klebsiella Species|PID due to Klebsiella Species|Pelvic Inflammatory Disease due to Proteus Species|PID due to Proteus Species|Gynecologic Infection|Endometritis due to Enterobacter Species|Endometritis due to Klebsiella Species|Endometritis due to Escherichia Coli|Endometritis due to E. Coli|Endometritis due to Proteus Species|Skin and Soft Tissue Skin Infection|Infection of Skin and/or Subcutaneous Tissue|Skin and Skin Soft Tissue Escherichia Coli Infection|Skin and Skin Soft Tissue Proteus Infection|Skin and Skin Soft Tissue Infection due to Klebsiella|Skin and Skin Soft Tissue Infection due to Enterobacter|Skin and Skin Soft Tissue Infection due to Aerobacter|Skin and Skin Soft Tissue Enterobacter Infection|Skin and Skin Soft Tissue Pseudomonas Aeruginosa Infection|Skin and Skin Soft Tissue Infection due to Citrobacter|Skin and Skin Soft Tissue Infection due to Serratia|Gram-Negative Bacteremia| Blood Infection caused by the Bacteria Enterobacter|Escherichia Coli Bacteria in the Blood|Bacterial Blood Infection caused by Pseudomonas Aeruginosa|Blood Poisoning caused by Serratia Bacteria|Infection of the Blood by Klebsiella Pneumoniae Bacteria|Blood Poisoning caused by Proteus Bacteria|Bacterial Infection with Acute Bronchitis|Bacterial Pneumonia caused by Klebsiella|Pneumonia caused by the Bacteria Pseudomonas Aeruginosa|Bacterial Pneumonia caused by Haemophilus Influenzae|Pneumonia caused by E. Coli Bacteria|Pneumonia caused by Gram-Negative Bacteria|Pneumonia caused by the Bacteria Serratia|Pneumonia caused by the Bacteria Enterobacter|Pneumonia caused by Proteus Bacteria|Bronchitis caused by the Bacteria Haemophilus Influenzae|Bronchitis caused by the Bacteria Enterobacter Cloacae|Bronchitis caused by the Bacteria Klebsiella Pneumoniae|Bronchitis caused by E. Coli|Bronchitis caused by Pseudomonas Aeruginosa|Bronchitis caused by Proteus Species|Bronchitis caused by Serratia Species|Lower Respiratory Tract Infection|E. Coli Bacteria Infection of Abdominal Cavity Lining|Klebsiella Pneumoniae Infection of Abdominal Cavity Lining|Abdominal Cavity Lining Infection caused by Enterobacter|Pseudomonas Aeruginosa Abdominal Cavity Lining Infection|Peritonitis caused by Citrobacter Bacteria|Peritonitis caused by Serratia Species|Inflammation and Infection of the Abdomen Lining|Infection Within the Abdomen|Urinary Tract Infection|Infection of Urinary Tract due to Enterobacter Cloacae|Urinary Tract Infection due to E. Coli Bacteria|Urinary Tract Infection caused by Klebsiella Bacteria|Infection of the Urinary Tract caused by Proteus Bacteria|Infection of Urinary Tract due to Pseudomonas Aeruginosa|Urinary Tract Infection caused by Citrobacter|Urinary Tract Infection caused by Serratia|E. Coli Bacteria Infection of the Female Pelvic Organs|Infection of Female Pelvic Organs due to Enterobacter|Infection of Female Pelvic Organs caused by Klebsiella|Infection of Female Pelvic Organs caused by Proteus|Pelvic Inflammatory Disease|Infection of a Woman's Reproductive Organs|Inflammation of the Endometrium|Infection of Lining of the Uterus caused by Enterobacter|Infection of Lining of the Uterus caused by Klebsiella|Infection of the Lining of the Uterus caused by E. Coli|Infection of the Lining of the Uterus caused by Proteus|Skin Infection|Skin Infection due to E. Coli Bacteria|Skin Infection due to Proteus Bacteria|Skin Infection due to Klebsiella Bacteria|Skin Infection due to Enterobacter Bacteria|Skin Infection due to Pseudomonas Aeruginosa Bacteria|Skin Infection due to Citrobacter Bacteria|Skin Infection due to Serratia Bacteria|Gram-Negative Bacteria in the Blood| Infection of the Larynx, Trachea, Bronchi or Lungs|Chest Infection|Chest Cold|Urinary Infections| LRTI|UTI|PID| Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First DataBank, Inc., 2012. This copyrighted material has been downloaded from a licensed data provider. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. 附件： 201032321370727.pdf    --------------------------------------------------------------- 注：以下产品不同规格和不同的价格，购买时请以电话咨询为准！ -------------------------------------------------------------== 产地国家: 美国 原产地英文商品名: AZACTAM IN DEXTROSE 2g/50ml/bag 24bags/case 原产地英文药品名: AZTREONAM/DEXTROSE-WATER 中文参考商品译名: AZACTAM IN 葡萄糖 2克/50毫升/袋 24袋/箱 中文参考药品译名: 氨曲南/葡萄糖-水 生产厂家中文参考译名: 百时美施贵宝 生产厂家英文名: BRISTOL MYERS SQUIBB ------------------------------------------------------------ 产地国家: 美国 原产地英文商品名: AZACTAM IN DEXTROSE 1g/50ml/bag 24bags/case 原产地英文药品名: AZTREONAM/DEXTROSE-WATER 中文参考商品译名: AZACTAM IN 葡萄糖 1克/50毫升/袋 24袋/箱 中文参考药品译名: 氨曲南/葡萄糖-水 生产厂家中文参考译名: 百时美施贵宝 生产厂家英文名: BRISTOL MYERS SQUIBB