英文药名：LEGALON SIL(SILIBININ) 中文药名：水飞蓟宾注射溶液剂 生产厂家：ROTTAPHARM/MADAUS GmbH 药品介绍： 本品为欧洲大陆传统的保肝药物，对病毒性慢性肝炎具有改善症状和肝脏生化功能的作用，部分患者的肝组织病理学也有一定程度改善，曾用于治疗中毒性肝炎，酒精性肝病，代谢性脂肪肝，对早期肝硬化也有一定疗效。但本品奏效缓慢，一般需1～2个月，才可逐渐见效，疗程至少3～6个月。 药理作用 本药系从菊利植物水飞蓟(Silybum marianum)果实中提取分离而得的一种黄酮类化合物，具有明显的保护和稳定肝细胞膜的作用，可以改善肝功能，产生降酶效果，且不易发生酶反跳。本药能稳定肝细胞膜及保持其完整性，并可促进肝细胞超微结构复原，促进正常肝细胞的分裂及生长，提高肝细胞合成RNA及蛋白质的能力，提高网状内皮系统制造巨噬细胞的能力，并加强巨噬细胞的活性，加速病毒的清除。同时，本药可促进脂肪转移及抗氧化作用，防止脂肪过度氧化及浸润，减轻肝脏脂肪变性；并可促进肝脏的代谢功能，增强其解毒作用，降低毒物对肝细胞的损伤。因此，本药具有保护正常肝脏细胞、促进受损害细胞膜复原的功效。 LEGALON SIL INJ PLV SOL 4X350MG Name of the product LEGALON SIL Supplement INJ PLV SOL 4X350MG Route Injection  Pharmaceutical form Powder for solution for injection  Package 4 Strenght 350MG Wrap type Vial  Legal status na lékařský předpis  Active substance SILIBININ DISODIUM DISUCCINATE (SILIBININI DINATRII DISUCCINAS)  ATC group A05BA03  ATC group name Silymarin  ----------------------------------------- Generic name: Silibinin Brand names: Legalon SIL and others Manufacturer: Various Silibinin (INN), also known as silybin, is the major active constituent of silymarin, the mixture of flavonolignans extracted from blessed milk thistle (Silybum marianum). It is used in the treatment and prevention of liver diseases because of its hepatoprotective (antihepatotoxic) properties. Clinical tests have also shown its ability to protect against certain types of cancer (skin and prostate), probably due to its antioxidant properties. Trade name of the product: Legalon SIL Pharmaceutical active ingredients: Silibinin Disodium Dihemisuccinate           Available forms, composition and doses of Legalon SIL: Injectable; Injection; Silibinin Disodium Dihemisuccinate 350 mg             Legalon SIL medical category: Human: Flavonolignans mixtures Milk thistle seeds standardized extracts      Indications and usages, anatomical therapeutic chemical and diseases classification codes: ATC ICD-10 Pharmaceutical companies: manufacturers, researchers, developers, local distributors and suppliers: --------------------------------------------------------------- 产地国家: 欧洲共同体国家 原产地英文商品名: LEGALON SIL POWDER AND SOLVENT SOLUTION FOR INFUSION 350MG/BOTTLE 4BOTTLES/BOX 原产地英文药品名: SILIBININ 原产地英文化合物名称: 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy -4-oxobenzopyran-2-yl)benzodioxin 中文参考商品译名: LEGALON SIL含粉剂和稀释剂的注射溶液剂 350毫克/瓶 4瓶/盒 中文参考药品译名: 水飞蓟宾 生产厂家中文参考译名: ROTTAPHARM/MADAUS GmbH 生产厂家英文名: ROTTAPHARM/MADAUS GmbH