【药物名称】Eszopiclone, (+)-Zopiclone, (S)-Zopiclone, Estorra
【化学名】(+)-6-(5-Chloro-2-pyridyl)-7(S)-(4-methylpiperazin-1-ylcarbonyloxy)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one; (+)-4-Methylpiperazine-1-carboxylic acid 6-(5-chloro-2-pyridyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5(S)-yl ester
【CAS登记号】138729-47-2, 138680-08-7 ((R)-isomer)
【结构式】
【分子式】C17-H17-Cl-N6-O3
【分子量】388.8133
【原研厂家】Aventis Pharma (Originator), Sepracor (Licensee)
【作用类别】PSYCHOPHARMACOLOGIC DRUGS, Sedative/Hypnotics, Sleep Disorders, Treatment of, GABAergic Transmission Enhancers
【研发状态】Pre-Registered
Therapeutic category: Non-benzodiazepine sedative
Composition: Each tablet contains Eszopiclone …1 mg / 2mg / 3mg
Indication: Insomnia
Dose (adults): 1-3 mg before bedtime
Advantages:
Lesser number of anticholinergic side effects as compared to racemic zopiclone.