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当前位置:药品说明书与价格首页 >> 糖尿病 >> 新药推荐 >> NovoLog injection(门冬胰岛素[重组]注射液)

NovoLog injection(门冬胰岛素[重组]注射液)

2014-02-27 02:58:24  作者:新特药房  来源:互联网  浏览次数:268  文字大小:【】【】【
简介: 英文药名:NOVOLOG(insulin aspart [recombinant]) 中文药名:门冬胰岛素[重组]注射液 生产厂家:诺和诺德药品介绍通用名:门冬胰岛素注射液成份门冬胰岛素(通过基因重组技术,利用酵母生产的)。1单 ...

英文药名:NOVOLOG(insulin aspart [recombinant])

中文药名:门冬胰岛素[重组]注射液

生产厂家:诺和诺德
药品介绍
通用名:门冬胰岛素注射液
成份
门冬胰岛素(通过基因重组技术,利用酵母生产的)。
1单位(1 U)相当于6nmol,0.035mg不含盐的无水门冬胰岛素。
化学结构式:
分子式:C256H381N65O79S6
分子量:5826
其他成份:甘油、苯酚、间甲酚、氯化锌、二水合磷酸氢二钠、氯化钠、盐酸和/或氢氧化钠(pH值调节剂)、注射用水。
性状
该品为无色澄明液体。
适应症
用于治疗糖尿病


NOVOLOG Rx
Generic Name and Formulations:
Insulin aspart (rDNA origin) 100 Units/mL; soln for SC inj, continuous subcutaneous insulin infusion (CSII), IV infusion; contains zinc, m-cresol.

Company:
Novo Nordisk
Indications for NOVOLOG:
Diabetes.

Adult:
For SC inj, CSII, or IV infusion: see full labeling. Onset approx ≤15 mins, peak approx 1–3hrs, duration approx 3–5hrs.

Children:
<2yrs: not recommended. 2–4yrs: use SC inj only. ≥4yrs: may use SC inj or CSII: see full labeling. Onset approx ≤15 mins, peak approx 1–3hrs, duration approx 3–5hrs.

Contraindications:
During episodes of hypoglycemia.

Warnings/Precautions:
Instruct patients on diet, exercise, blood or urine testing, proper administration of insulin, change in species of origin, type or purity of insulin, and management of hypoglycemia. Do not reuse or share pens, needles, cartridges, or syringes between patients. Dosage increase may be required during infection, illness, stress, trauma, and pregnancy. Dosage decrease may be needed with renal or hepatic dysfunction. Pregnancy (Cat.B). Nursing mothers.

Interactions:
Concomitant thiazolidinediones (TZDs) may cause fluid retention and heart failure; consider dose reduction or discontinue TZDs. Potentiated by oral antidiabetic agents, pramlintide, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, propoxyphene, salicylates, somatostatin analog, sulfonamide antibiotics. Antagonized by corticosteroids, isoniazid, niacin, danazol, diuretics, thiazides, phenothiazines, sympathomimetics, somatropin, thyroid hormones, estrogens, progestogens, atypical antipsychotics. Variable effects with β-blockers, clonidine, lithium salts, alcohol, pentamidine. CSII: Do not mix with other insulins or diluent when pump is used.

Adverse Reactions:
Hypoglycemia, hypokalemia, local or systemic allergy, lipodystrophy, edema.

How Supplied:
Vials (10mL)—1; FlexPen (3mL prefilled syringe)—5; PenFill (3mL cartridges)—5; NovoPen Echo (inj device, uses PenFill cartridges)—1

责任编辑:admin


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