部份中文阿普唑仑处方资料(仅供参考) 【中文品名】阿普唑仑 【药效类别】催眠镇静药>苯并二氮卓类 【通用药名】ALPRAZOLAM 【别 名】安宁甲,佳乐定,甲基三唑氯安定, 三唑安定, 佳静安定,Xanax,U-31889,D- 65MT,TUS-1 【化学名称】 8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine 【CA登记号】[28981-97-7] 【结 构 式】
【分 子 式】C17H13ClN4 【分 子 量】308.76 【收录药典】JP14 【开发单位】Upjohn (美国) 【首次上市】1981年,美国 【性 状】白色或类白色结晶性粉未,微苦。易溶于三氯甲烷,略溶于乙醇、丙酮,几乎不溶于水和乙醚。mp229~230℃。 【用 途】苯并二氮卓类镇静催眠药。用于治疗焦虑症或焦虑症状的短期治疗。亦可用于伴有忧郁症状的焦虑症。还可用于在治疗中的开角型青光眼患者。 注:本品属管控药
生产厂家:美国辉瑞公司 完整资料附件:https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=AA58FFF3-C297-49BE-838B-599C32AD9835 Xanax XR(Alprazolam Tablets) XANAX XR CIV Generic Name and Formulations: Alprazolam 0.5mg, 1mg, 2mg, 3mg; ext-rel tabs. Company: Pfizer Inc.
Select therapeutic use: Anxiety/OCD Indications for XANAX XR: Panic disorder.
Adult: Swallow whole. ≥18yrs: initially 0.5–1mg once daily, preferably in the AM; increase at intervals of at least 3–4 days by up to 1mg/day. Taper no faster than by 0.5mg every 3 days. Usual range: 3–6mg/day; max 10mg/day. Elderly or debilitated: initially 0.5mg/day. Switching from immediate-release alprazolam: give total daily dose of immediate-release once daily, preferably in the AM.
Children: <18yrs: not recommended.
Contraindications: Acute narrow-angle glaucoma. Concomitant itraconazole, ketoconazole.
Warnings/Precautions: Not for use in untreated open-angle glaucoma. Reevaluate periodically. Change dose gradually. Withdrawal symptoms on abrupt cessation or dose reduction. Suicidal ideation. Psychosis. Mania. Renal, cardiovascular, hepatic, pulmonary dysfunction (monitor). Obesity. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.D), nursing mothers: not recommended.
Interactions: See Contraindications; other azole antifungals: not recommended. Potentiates CNS depression with alcohol, psychotropics, anticonvulsants, other CNS depressants. Potentiated by CYP3A inhibitors; reduce alprazolam dose; caution with cimetidine, nefazodone, fluvoxamine; caution with weaker CYP3A inhibitors (eg, fluoxetine, propoxyphene, oral contraceptives). Antagonized by CYP3A inducers (eg, carbamazepine). May increase levels of imipramine, desipramine.
See Also: XANAX
Pharmacological Class: Benzodiazepine.
Adverse Reactions: CNS depression; impaired memory, coordination, or attention; dysarthria, ataxia, arthralgia, dyspnea, paradoxical excitement, increased salivation, withdrawal seizures, tremors, decreased libido, sexual dysfunction.
How Supplied: XR—60; Tabs 0.25mg, 0.5mg, 1mg—100, 500, 1000; 2mg—100, 500 |