英文药名: Synarel (Nafarelin Acetate) 中文药名: 那法瑞林鼻喷剂,醋酸萘瑞林,萘法林,萘瑞林 生产厂家: Pfizer 那法瑞林 Nafarelin（萘瑞林，Synarel） 生产厂家 Pfizer 辉瑞 制剂　 喷鼻液：每瓶 (2mg/ml)，60 Doses 适应症　 GnRH类似物。作用同布舍瑞林。鼻腔给药吸收迅速，经30分钟血浓度达峰值，t1/23小时。临床主要用于子宫内膜异位症、子宫肌瘤、多毛症等。 用法用量　 鼻腔：清晨和傍晚各1次200μg，即每天400μg(于月经周期2～4日开始） 任何疑问，请遵医嘱！ 注意事项　 面部发热、性欲减低、阴道干燥、头痛、情绪变态等。 过敏阴道出血者、孕妇、哺乳期忌用。 SYNAREL Generic Name for SYNAREL Nafarelin (as acetate) 200micrograms/spray; intranasal soln. Legal Classification: Rx Pharmacological Class for SYNAREL GnRH analogue. Manufacturer of SYNAREL Pfizer Labs Indications for SYNAREL Central precocious puberty. Adult dose for SYNAREL Not applicable. Children's dosing for SYNAREL 1600micrograms daily as 2 sprays into each nostril in the AM and PM; may increase to 1800micrograms daily as 3 sprays into alternating nostrils 3 times daily. Allow 30 seconds to elapse between sprays. Discontinue when resumption of puberty is desired. Contraindications for SYNAREL Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers. Warnings/Precautions for SYNAREL Exclude pregnancy before treatment. Confirm diagnosis. Monitor hormonal effects within first 6–8 weeks, growth velocity and bone age velocity within first 3–6 months. Avoid sneezing during or immediately after dosing. Nursing mothers: not recommended. Interactions for SYNAREL Avoid nasal decongestants until at least 2 hrs after dosing. Adverse Reactions for SYNAREL Acne, transient breast enlargement, vaginal bleeding or discharge, emotional lability, transient increase in pubic hair, body odor, seborrhea, hot flashes, rhinitis; occasional pituitary gland morphological changes. How is SYNAREL supplied? Nasal spray—8mL (60 sprays)