部分中文BUFFERIN(バファリン)处方资料（仅供参考） Brand Name Bufferin Common Name acetylsalicylic acid (ASA)DIN (Drug Identification Number) BUFFERIN 325MG TABLET BUFFERIN EXTRA -STRENGTH 500MG TABLET How does this medication work? What will it do for me? Acetylsalicylic acid (ASA) belongs to the group of medications called analgesics (pain relievers), antipyretics (fever reducers), anti-inflammatories (inflammation reducers), and platelet aggregation inhibitors (anticlotting agents). It works by interfering with the production of compounds in the body that cause pain, fever, inflammation, and blood clots. Acetylsalicylic acid (ASA) is used to relieve pain, fever, and inflammation in various conditions such as lower back and neck pain, the flu, common cold, burns, menstrual pain, headache, migraines, osteoarthritis, rheumatoid arthritis, sprains and strains, nerve pain, toothache, muscle pain, bursitis (inflammation of a bursa, a fluid-filled sac located around joints and near the bones), and following surgical and dental procedures. ASA is also used for rheumatic fever in combination with other medications. In these situations, ASA is used on an as-needed basis. Because of the antiplatelet (anticlotting) properties of ASA, it may be used under the supervision of your doctor to:prevent a first nonfatal heart attack in people who are at increased risk of having a heart attack as determined by their doctor (factors that increase your risk of heart attack include: smoking, high blood pressure, high cholesterol, inactive lifestyle, stress, and being overweight) prevent a second heart attack or stroke reduce the risk of "mini-stroke" or transient ischemic attack (TIA) reduce the clotting properties of platelets for people who have had carotid artery surgery to prevent the recurrence of TIA and for people receiving hemodialysis through a silicone rubber access prevent blood clots for people who have had a total hip replacement ASA can also be used during a heart attack to reduce the risk of dying from the heart attack. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. How should I use this medication? The recommended dose of ASA for adults varies widely according to the particular condition being treated. Adult dosage:To treat pain or fever in adults, the recommended dose is 325 mg to 650 mg every 4 to 6 hours as needed. The maximum daily dose is 4,000 mg, unless otherwise directed by your doctor. For adults with conditions caused by inflammation such as rheumatoid arthritis, the usual dose is 975 mg 4 to 6 times daily on a regular basis. Sometimes, higher doses may be used. To treat migraine headache pain, the recommended adult dose is 1,000 mg at the onset of pain or symptoms. To prevent a first nonfatal heart attack, TIA, a second heart attack, or a second stroke, the usual dose for adults is 80 mg to 325 mg once daily, depending on your doctor's instructions. During a heart attack, the recommended ASA dose is 160 mg to 162.5 mg chewed or crushed. As soon as you suspect you are having a heart attack, call an ambulance and take the recommended ASA dose, providing you have no allergies or other conditions or factors that would indicate ASA is not right for you. To prevent blood clots after total hip replacement surgery, the recommended dose is 650 mg twice a day started one day before surgery and continued for 14 days after surgery unless otherwise directed by your doctor. For rheumatic fever, the usual dose of ASA is 80 mg per kilogram of body weight per day in divided doses. Children's dosage:This medication is not recommended to be used by children, teenagers, or young adults to treat fever (see the section, "Are there any other precautions or warnings for this medication). However, if recommended by a doctor in other circumstances such as to treat pain, the recommended dose is 10 mg to 15 mg per kilogram of body weight every 6 hours as needed to a maximum of 2,400 mg per day (ask your doctor or pharmacist to give you the correct dose if you are unsure). When used as an anti-inflammatory, the recommended dose is 60 mg to 125 mg per kilogram of body weight daily in 4 to 6divided doses. Because ASA can cause stomach irritation and upset, specially coated tablets called enteric-coated are recommended when taking ASA for long periods of time. This special coating prevents the tablet from dissolving until it has passed the stomach and moved into the small intestine. This coating also means that it will take longer for the medication to take effect, so do not use enteric-coated tablets when fast relief is required. ASA should also be taken with food to prevent stomach upset. Enteric-coated medications can be taken without food. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way you are taking the medication without talking to your doctor. It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature, protect it from moisture, and keep it out of the reach of children. This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired. What form(s) does this medication come in? This medication is available as 325 mg and 500 mg tablets. Who should NOT take this medication? Do not take this medication if you:are allergic to ASA or any ingredients of the medication are in your last trimester of pregnancy are prone to bleeding are using methotrexate at doses of 15 mg or more per week have an active peptic ulcer have had a severe allergic or asthmatic reaction caused by salicylates, ASA, or nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., diclofenac, ibuprofen, indomethacin, naproxen) Bufferin（巴非林A片[バファリン]） 产品概述　　 阿司匹林抗血小板聚集的作用在临床上得到广泛应用，在预防和治疗心肌梗塞和脑梗塞方面有较好的疗效，是心血管疾病二级预防中的首选药，长期使用可降低发病率和死亡率。 但是长期服用阿司匹林会导致胃肠道反应，胃肠道出血或溃疡。铝镁匹林片Ⅱ是阿司匹林复方制剂，每片含阿司匹林81mg、甘羟铝11mg、重质碳酸镁22mg，甘羟铝和重质碳酸镁为酸制剂，保护胃粘膜，可减轻阿司匹林的胃肠不良反应。 产品特点 > 胃保护　　 铝镁匹林片区别于普通阿司匹林片的最大特点和优势在于：胃部不良反应发生率的降低。 阿司匹林通过不可逆的抑制花生四烯酸的合成，阻断血栓素A2合成，从而达到抗血栓的效果。但由于其游离羧基的存在，使胃部的酸度增加而造成胃粘膜不同程度的刺激性损伤，会引起胃膜轻度糜烂而形成溃疡、出血、穿孔及十二指肠出血等症。 铝镁匹林片含有甘羟铝，可中和胃酸，改善胃酸增多、上腹部疼痛等临床症状，并有收敛、止血等作用；重质碳酸镁为抗酸药，可减低阿司匹林对胃的不良刺激，显著降低胃粘膜糜烂和溃疡的发生率，从而起到对胃的保护作用。 > 安全性好，更适合长期服用 临床研究表明，铝镁匹林片用药24周，疗效稳定，且与试验相关的不良事件发生率显著低于服用普通阿司匹林片。 本品进入胃部后，甘羟铝和重质碳酸镁能够形成碱性环境，显著降低胃部酸度，避免了胃粘膜受到刺激，既达到了预期疗效，又避免了普通阿司匹林引起的胃肠道反应等不良症状，因而从安全性角度分析，铝镁匹林片更适合长期服用。 > 吸收度强　　 药物吸收速度受药片的溶解速度、胃粘膜表面的pH值、胃排空时间等多种因素的影响。铝镁匹林片创新性的将阿司匹林与碱性药物（甘羟铝和重质碳酸镁）并用，达到全新的效果，碱性药物可使胃排空加快，促使药物迅速进入主要吸收部位——小肠。 长期服用安全性依据　　 本复方在日本自2000年上市，商品名为BUFFERIN 81MG（巴非林81mg），由日本LION公司生产，使用至今并无与铝蓄积毒性相关的不良反应报道。 附件: 201221423470929.PDF    201221423470426.PDF --------------------------------------------------------------- 注：以下产品不同规格和不同价格，购买时请以电话咨询为准！ --------------------------------------------------------------- 产地国家: 日本 原产地英文商品名: Bufferin(バファリン) 81mg/tab 100tabs/box 原产地英文药品名: Aspirin/Aluminum Glycinate/Magnesium Carbonate 中文参考商品译名: 巴非林(バファリン) 81毫克/片 100片/盒 中文参考药品译名: 阿司匹林/甘羟铝/碳酸镁 生产厂家中文参考译名: Lion 生产厂家英文名: Lion ----------------------------------------------------------------- 产地国家: 日本 原产地英文商品名: Bufferin A(バファリン) (330mg/100mg)/tab 40tabs/box 原产地英文药品名: Acetylsalicylic acid (aspirin)/Dibuffer HT (synthetic hydrotalcite) 中文参考商品译名: 巴非林A(バファリン) （330毫克/100毫克）/片 40片/盒 中文参考药品译名: 乙酰水杨酸（阿司匹林）/羟色胺（合成水滑石） 生产厂家中文参考译名: Lion 生产厂家英文名: Lion ----------------------------------------------------------------- 产地国家: 日本 原产地英文商品名: Bufferin A(バファリン) (330mg/100mg)/tab 80tabs/box 原产地英文药品名: Acetylsalicylic acid (aspirin)/Dibuffer HT (synthetic hydrotalcite) 中文参考商品译名: 巴非林A(バファリン) （330毫克/100毫克）/片 80片/盒 中文参考药品译名: 乙酰水杨酸（阿司匹林）/羟色胺（合成水滑石） 生产厂家中文参考译名: Lion 生产厂家英文名: Lion