复方庆大霉素滴眼液、眼膏属于化药3.2类，为硫酸庆大霉素与醋酸泼尼松龙的复方制剂，用于浅表细菌感染或存在细菌感染的危险，可用皮质激素药物治疗的眼科炎症如：结膜炎、角膜炎、慢性眼前部色素层炎症和化学物质、辐射、烧伤、异物穿透等造成的眼部伤害，能有效预防敏感菌对眼部的伤害。 硫酸庆大霉素目前广泛用于各种细菌性眼内炎、浅表性眼科感染及眼科手术后的预防感染治疗。醋酸泼尼松龙广泛用于各种原因引起的眼科炎症和白内障手术后炎症的抗炎治疗。对严重的眼科感染和炎症，则采两者联合用药治疗。两药的复方眼用混悬滴眼剂，由美国眼力健公司研制并于1988年获FDA批准并供应临床。国内目前尚无两种药物的复方眼科制剂供应，临床上常将两种药物的制剂临时混合用于严重的眼科炎症。 药品名称 常用名：硫酸庆大霉素， 英文名：Gentamicin Sulfate ， 作用类别：本品为眼科用药类。 药理作用　 本品为氨基糖苷类广谱抗生素，其作用机制主要是抑制细菌合成蛋白质。对眼部常见革兰阴性菌有抗菌作用。 适应症　 用于细菌性结膜炎，麦粒肿及细菌性眼睑炎。 用法用量　　 滴眼。将本品滴入眼睑内，一次1～2滴，一日3～5次。或遵医嘱！ 不良反应　 1.轻微刺激感。 2.偶见过敏反应，出现充血、眼痒、水肿等症状。 禁忌症　 对本品或其他氨基糖苷类抗生素过敏者禁用。 注意事项　　 1. 对本品过敏者禁用。 2. 滴眼时请勿使瓶口接触手和眼睛。 3. 本品不宜长期连续使用，使用3～4日症状未缓解时，应停药就医。 4. 若出现充血、眼痒、水肿等症状，应停药就医。 5. 使用后请拧紧瓶盖，以防污染。 6. 当本品性状发生改变时禁用。 7. 如使用过量或发生严重不良反应时应立即就医。 8. 儿童必须在成人监护下使用。 9. 请将此药品放在儿童不能接触的地方。 药物相互作用　　 1. 使用本品时不能同时使用其他滴眼剂。 2. 如正在使用其他药品，使用本品前请咨询医师或药师。  Pred-G Generic Name: gentamicin and prednisolone ophthalmic (JEN ta MYE sin pred NIS oh lone) Brand Names: Pred-G, Pred-G S.O.P. What is Pred-G (gentamicin and prednisolone ophthalmic)? Gentamicin is an antibiotic. It is used to treat bacterial infections. Prednisolone is a steroid. It is used to treat the swelling associated with bacterial infections of the eye. Gentamicin and prednisolone ophthalmic is used to treat bacterial infections of the eyes. Gentamicin and prednisolone ophthalmic may also be used for purposes other than those listed in this medication guide. What is the most important information I should know about Pred-G (gentamicin and prednisolone ophthalmic)? Contact your doctor if your symptoms begin to get worse or if you do not see any improvement in your condition after a few days. Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear duct. Who should not use Pred-G (gentamicin and prednisolone ophthalmic)? Do not use gentamicin and prednisolone ophthalmic if you have a viral or fungal infection in your eye. It is used to treat infections caused by bacteria only. It is not known whether gentamicin and prednisolone ophthalmic will harm an unborn baby. Talk to your doctor before using this medication if you are pregnant. It is also not known whether gentamicin and prednisolone ophthalmic passes into breast milk. Talk to your doctor before using this medication if you are breast-feeding a baby. How should I use Pred-G (gentamicin and prednisolone ophthalmic)? Use gentamicin and prednisolone ophthalmic eyedrops or ointment exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Wash your hands before and after using your eyedrops or ointment. To apply the eyedrops: Shake the drops gently to be sure the medicine is well mixed. Tilt your head back slightly and pull down on your lower eyelid. Position the dropper above your eye. Look up and away from the dropper. Squeeze out a drop and close your eye. Apply gentle pressure to the inside corner of your eye (near your nose) for about 1 minute to prevent the liquid from draining down your tear duct. If you are using more than one drop in the same eye or drops in both eyes, repeat the process with about 5 minutes between drops. To apply the ointment: Hold the tube in your hand for a few minutes to warm it up so that the ointment comes out easily. Tilt your head back slightly and pull down gently on your lower eyelid. Apply a thin film of the ointment into your lower eyelid. Close your eye and roll your eyeball around in all directions for 1 to 2 minutes. If you are applying another eye medication, allow at least 10 minutes before your next application. Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Do not use any eyedrop that is discolored or has particles in it. Store gentamicin and prednisolone ophthalmic at room temperature away from moisture and heat. Keep the bottle or tube properly capped. What happens if I miss a dose? Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication. What happens if I overdose? An overdose of this medication is unlikely to occur. If you do suspect an overdose, wash the eye with water and call an emergency room or poison control center near you. If the drops or ointment have been ingested, drink plenty of fluid and call an emergency center for advice. What should I avoid while using Pred-G (gentamicin and prednisolone ophthalmic)? Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Use caution when driving, operating machinery, or performing other hazardous activities. Gentamicin and prednisolone ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities. Use caution with contact lenses. Wear them only if your doctor approves. After applying this medication, wait at least 15 minutes before inserting contact lenses. Avoid other eye medications unless your doctor approves. Pred-G (gentamicin and prednisolone ophthalmic) side effects Serious side effects are not expected with this medication. Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect Pred-G (gentamicin and prednisolone ophthalmic)? Avoid other eye medications unless they are approved by your doctor. Before using this medication, tell your doctor if you are taking an oral steroid medication such as prednisone (Deltasone, Orasone, others). Drugs other than those listed here may also interact with gentamicin and prednisolone ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. Compare Pred-G with other medications Blepharitis Conjunctivitis, Bacterial Keratitis Keratoconjunctivitis Uveitis Where can I get more information? Your pharmacist has additional information about gentamicin and prednisolone ophthalmic written for health professionals that you may read. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.