部份中文奥扎格雷钠处方资料（仅供参考） 【中文品名】奥扎格雷钠 【药效类别】抗凝药>抗血小板聚集药 【通用药名】OZAGREL SODIUM 【别　　名】Cataclot，Xanbon 【化学名称】 2-Propenoic acid, 3-[4-(1H-imidazol-1-ylmethyl)phenyl]-, (E)-, sodium salt 【CA登记号】[82571-53-7] 【结 构 式】 【分 子 式】C13H11N2NaO2 【分 子 量】250.22 【收录药典】 【开发单位】小野药品株式会社 (日本) 【首次上市】1987年，日本 【性　　状】白色结晶或结晶性粉末，无臭，味酸或苦。易溶于水，稍易溶于甲醇，几乎不溶于无水乙醇、丙酮和乙醚，遇光稍不稳定，mp214~217℃。 【用　　途】抗凝血药。可强烈抑制血栓素(TX)合成酶。用于蛛网膜下腔出血术后脑血管痉孪、伴随血管痉孪的脑缺血症状。 【用法用量】 成人一次80mg，一天2次，溶于500ml生理盐水或5%葡萄糖溶液中，静脉滴注，2周为一疗程。 キサンボン注射用20mg／キサンボン注射用40mg XANBON injectable（Ozagrel sodium） XANBON injectable 20mg [cerebral thrombosis]（キサンボン注射用20mg［脳血栓症/くも膜下出血術後］） Brand name : XANBON injectable 20mg [cerebral thrombosis] 　Active ingredient: Ozagrel sodium 　Dosage form: injection 　Print on wrapping ------------------------------------ XANBON injectable 40mg [cerebral thrombosis]（キサンボン注射用40mg［脳血栓症/くも膜下出血術後］） Brand name : XANBON injectable 40mg [cerebral thrombosis] 　Active ingredient: Ozagrel sodium 　Dosage form: injection 　Print on wrapping: Effects of this medicine This medicine suppresses production of thromboxane A2 and promotes production of prostacyclin by selectively inhibiting thromboxane synthetase, leading to improvements in the imbalance between thromboxane A2 and prostacyclin, as well as to antiplatelet aggregation action. It is usually used to improve paralysis of limbs associated with cerebral thrombosis in the acute phase, during which the blood vessels in the brain get clogged. Before using this medicine, be sure to tell your doctor and pharmacist •If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If you have bleeding (hemorrhagic cerebral infarction, epidural bleeding, intra-cerebral bleeding, primary intraventricular bleeding), brain embolism, heart problems, cortical symptoms such as disturbance of consciousness or speech loss/agnosia or cardioembolic stroke. •If you are pregnant or breastfeeding. •If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.) Dosing schedule (How to take this medicine) •Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>> •In general, inject intravenously for 2 hours twice a day in the morning and evening. •In general, inject every day for 2 consecutive weeks. Precautions while taking this medicine • Possible adverse reactions to this medicine The most commonly reported adverse reactions include liver dysfunction, hemorrhagic adverse reactions (hemorrhagic cerebral infarction/cerebral bleeding/gastrointestinal bleeding/subcutaneous bleeding, etc.), rash, anemia, asthma (like) attack, itch, hives, erythema and blood pressure decreased. If any of these symptoms occur, consult with your doctor or pharmacist. The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. •headache, bloody stool, subcutaneous bleeding [bleeding] •blood pressure decreased, respiratory distress, pharyngeal edema [shock, anaphylactoid symptoms] •yellow discoloration of the skin and the white of eyes, general malaise, loss of appetite  [liver dysfunction, jaundice] •prolonged bleeding, gum bleeding, bruise [platelets decreased] •fever, sore throat, general malaise [white blood cell decreased, granulocytopenia] The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. Kissei Pharmaceutical Co., Ltd.Injection Revised: 8/2012 The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment. http://www.info.pmda.go.jp/go/pack/3999411D1064_1_08/ --------------------------------------------- 产地国家：日本 原产地英文商品名: XANBON(キサンボン注射用) 40MG/VIAL 10VIALS/BOX 原产地英文药品名: OZAGREL SODIUM 中文参考商品译名: XANBON(キサンボン注射用) 40毫克/瓶 10瓶/盒 中文参考药品译名: 奥扎格雷钠 生产厂家中文参考译名: 日本橘生制药 生产厂家英文名: Kissei ------------------------------------------------ 产地国家：日本 原产地英文商品名: XANBON(キサンボン注射用) 20MG/VIAL 10VIALS/BOX 原产地英文药品名: OZAGREL SODIUM 中文参考商品译名: XANBON(キサンボン注射用) 20毫克/瓶 10瓶/盒 中文参考药品译名: 奥扎格雷钠 生产厂家中文参考译名: 日本橘生制药 生产厂家英文名: Kissei