英文药名: Anaprox DS(Naproxen Sodium Double Strength Tablets) 中文药名: 萘普生钠双强度片 品牌药生产厂家: Roche Pharmaceuticals 药物名称和成分 英文药名: Anaprox DS (Naproxen Sodium Double Strength Tablets) 本品为非甾体抗炎药。适用于缓解各种轻度至中等度的疼痛,如拔牙及其他手术后的疼痛、原发性痛经及头痛等。也适用于类风湿关节炎、骨关节炎、强直性脊柱炎、幼年型关节炎(Juvenile arthritis)、肌腱炎、滑囊炎及急性痛风性关节炎,对于关节炎的疼痛、肿胀及活动受限均有缓解症状的作用。与阿司匹林和吲哚美辛比较,症状缓解的效应相仿,但胃肠道和神经系统的不良反应的发生率和严重程度均较低。 0.550g(相当于萘普生550mg) 口服 1.皮肤瘙痒、呼吸短促、呼吸困难、哮喘、耳鸣、下肢水肿、胃烧灼感、消化不良、胃痛或不适、便秘、头晕、嗜睡、头痛、恶心及呕吐等,发生率一般为3%~9%。 对阿司林过敏者禁止使用,对伴有消化道溃疡或消化道溃疡史者慎用。 1.交叉过敏。对阿司匹林或其他非甾体抗炎药过敏者,对本品也过敏。 禁用。 小儿常用量 抗风湿,每日按体重10mg/kg,分2次服。 1.饮酒或与其他抗炎药同用时,胃肠道的不良反应增多,并有溃疡发生的危险。 萘普生具有剂量依赖性的抗炎镇痛和解热作用。抗炎作用强度约为等剂量保泰松的11倍,镇痛、解热作用是阿司匹林的7倍和22倍。抗炎、镇痛、解热作用相当于吲哚美辛。 萘普生游离酸和钠盐的应用等效剂量为1:1.1。口服后均易自胃肠道吸收,且完全,但其钠盐吸收速度更快,服药1小时后达血药峰浓度,游离酸则需2小时。胃内容物可延长其吸收时间,但不影响其吸收率。血浆蛋白的结合率高(>99.5%)。可分布于全身组织,滑膜液中达有效浓度,并可透过胎盘,进入胎儿体内。经肝脏代谢,肾脏排泄,排泄物中大部分为代谢产物,少量原形。约有3%自粪便排出,1%乳汁分泌。血浆t1/2为13小时。本品亦可直肠给药,但吸收速度比口服慢。 遮光,密封,在凉处保存。 Anaprox-DS What is Anaprox-DS (naproxen)? Naproxen may also be used for other purposes not listed in this medication guide. What is the most important information I should know about Anaprox-DS (naproxen)? Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to naproxen (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen. Do not drink alcohol while taking naproxen. Alcohol can increase the risk of stomach bleeding caused by naproxen. Avoid prolonged exposure to sunlight. Naproxen can make your skin more sensitive to sunlight, and a sunburn may result. NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects. Do not use this medication if you are allergic to naproxen, or if you have a history of allergic reaction to aspirin or other NSAIDs. a history of heart attack, stroke, or blood clot; heart disease, congestive heart failure, high blood pressure; a history of stomach ulcers or bleeding; liver or kidney disease; polyps in your nose; a bleeding or blood clotting disorder; or if you smoke. FDA pregnancy category C. Before using naproxen, tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking naproxen during the last 3 months of pregnancy may result in birth defects. Do not take naproxen during pregnancy unless your doctor has told you to. Naproxen can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 2 years old without the advice of a doctor. How should I take Anaprox-DS (naproxen)? EC-Naprosyn is a slower-acting form of naproxen and this brand should be used only for treating arthritis or ankylosing spondylitis. Follow your doctor's instructions. Do not crush, chew, or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Store naproxen at room temperature away from moisture and heat. What happens if I overdose? black, bloody, or tarry stools; coughing up blood or vomit that looks like coffee grounds; swelling or rapid weight gain; urinating less than usual or not at all; nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; bruising, severe tingling, numbness, pain, muscle weakness; or fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions). Less serious side effects may include: upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas; dizziness, headache, nervousness; skin itching or rash; blurred vision; or ringing in your ears. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. 包装规格:550mg *100 片 |