部分中文美洛昔康处方资料（仅供参考） 美洛昔康( Meloxicam ) 化学名： 4-羟基-2-甲基-N-(5-甲基-1,3-噻唑-2-基)-2H-1,2-苯并噻嗪-3-羧酸乙酯 1,1-二氧化物 类别： 美洛昔康是非甾体抗炎药，用来减轻一些关节炎的症状，治疗风湿药 适应症： 使用于类风湿性关节炎的症状治疗，疼痛性骨关节炎（关节病、退行性骨关节病）的症状治疗。 用法用量： 口服，用水或流质送服吞咽。 类风湿性关节炎： 每天15mg（2片），根据治疗后反应，剂量可减至一日7.5mg（1片）。 骨关节炎： 一日7.5mg（1片），如果需要，剂量可增值一日15mg（2片）。 对于不良反应有可能增加的病人：治疗开始剂量一日7.5mg(1片)。 严重肾衰竭的病人透析时：剂量不应超过一日7.5mg（1片）。 本品每日最大建议剂量为15mg(2片)。 儿童适用的剂量尚未确定，目前只限于成人使用。 不良反应 根据国外研究资料报道，以下罗列的不良反应系在本品给药后发生，然而他们的发生频率是根据临床实验记录结果，而无论与本品用药是否有因果关系。这些信息是基于对3750个病人进行的超过18个月的临床实验得到的，病人每日口服本品剂量为7.5或15毫克。（治疗用药的平均时间为127天）。 1、胃肠道： 频率超过1％：消化不良、恶心、呕吐、腹痛、便秘、胀气、腹泻。频率介于0.1％和1％之间：短暂的肝功能指标异常（如转氨酶或胆红素升高）。食道炎、胃十二指肠溃疡，隐伏或肉眼可见的胃肠道出血。频率小于0.1％：胃肠道穿孔，结肠炎。 2、血液： 频率超过1％：贫血。介于0.1％和1％之间：血细胞计数失调，包括白细胞分类计数，白细胞减少和血小板减少，同时使用潜在的骨髓毒性药物，特别是氨甲喋呤，是导致出现血细胞减少的一个因素。 3、皮肤： 频率超过1％：瘙样、皮疹。介于0.1％和1％之间：口炎、寻麻疹。少于0.1％：感光过敏。 4 、呼吸道： 频率少于0.1％：已有报道在使用阿斯匹林或其他NSAID，包括本品之后有个体出现急性哮喘。 5、中枢神经系统： 频率多于1％：轻微头晕、头痛。介于0.1％和1％：眩晕、耳鸣、嗜睡。 6、心血管： 频率多于1％：水肿。介于0.1％和1％之间：血压升高、心悸、潮红。 7、泌尿系统： 介于0.1％和1％之间：肾功能指标异常（血清肌酐和／或血清尿素升高）。 禁忌 以下情况禁用： 对药物活性成分美洛昔康或其赋形剂已知过敏者。与乙酰水杨酸和其他NSAID可能会有交叉过敏反应。对使用乙酰水杨酸或其他NSAID后出现哮喘、鼻腔息肉、血管水肿或寻麻疹等症状的病人不宜使用本品。活动性消化性溃疡，严重肝功能不全者，非透析严重肾功能不全者，儿童和年龄小于15岁的青少年，孕妇或哺乳者。 　 孕妇及哺乳期妇女用药 虽然在临床前的试验中没有发现致畸作用，但本品不应用于孕妇和哺乳者。 儿童用药 儿童的适用剂量尚未确定，儿童和年龄小于15岁的青少年禁用。 老年用药 对可能有肝、肾及心功能不全的老年患者应慎用。 药物过量： 因为没有已知的解毒药，所以在过剂量情况时应采取胃排空及支持疗法。有临床试验表明消胆胺可促进本品的排泄。 贮藏： 遮光、密封保存。放在儿童伸手不及处。 Metacam (meloxicam) Uses Meloxicam is used to treat arthritis. It reduces pain, swelling, and stiffness of the joints. Meloxicam is known as a nonsteroidal anti-inflammatory drug (NSAID). If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section. OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat gout attacks. How to use meloxicam Read the Medication Guide provided by your pharmacist before you start taking meloxicam and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily. Drink a full glass of water (8 ounces/240 milliliters) with it unless your doctor tells you otherwise. Do not lie down for at least 10 minutes after taking this drug. If you are taking the liquid form of this medication, shake the bottle gently before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If stomach upset occurs while taking this medication, take it with food, milk, or an antacid. The dosage is based on your medical condition and response to treatment. The lowest effective dosage should always be used, and only for the prescribed length of time. Do not take more than 15 milligrams per day because higher doses increase the chance of stomach ulcers/bleeding. It may take up to two weeks before you get the full benefit of this drug. Use this medication regularly to get the most benefit from it. Remember to use it at the same time each day. Tell your doctor if your condition worsens. What conditions does meloxicam treat?Side Effects See also Warning section. Stomach upset, nausea, dizziness, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, persistent/severe headache, mental/mood changes, sudden/unexplained weight gain, swelling of the hands/feet, change in the amount of urine, unexplained stiff neck, unusual tiredness. This drug may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, including: dark urine, persistent nausea/vomiting/loss of appetite, stomach/abdominal pain, yellowing eyes/skin. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. List meloxicam side effects by likelihood and severity.Precautions Before taking meloxicam, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), liver disease, stomach/intestine/esophagus problems (such as bleeding, ulcers, recurring heartburn), heart disease (such as history of heart attack), high blood pressure, stroke, blood disorders (such as anemia, bleeding/clotting problems), growths in the nose (nasal polyps). Kidney problems can sometimes occur with the use of NSAID medications, including meloxicam. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have any unusual change in the amount of urine. This medication may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. This medication may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medication, may increase your risk for stomach bleeding. Limit alcohol and smoking. Consult your doctor or pharmacist for more information. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially stomach bleeding and kidney problems. Before using this medication, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage, trouble getting pregnant). Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery. It is unknown if this medication passes into breast milk. However, similar drugs pass into breast milk and are unlikely to harm a nursing infant. Consult your doctor before breast-feeding. What should I know regarding pregnancy, nursing and administering meloxicam to children or the elderly?Interactions Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), cidofovir, lithium, methotrexate (high-dose treatment), "water pills" (diuretics such as furosemide). This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others. If you are using the liquid form of meloxicam, tell your doctor if you are also using sodium polystyrene sulfonate. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as celecoxib, ibuprofen, or ketorolac). These drugs are similar to meloxicam and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details. Does meloxicam interact with other medications?Overdose If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: slow/shallow breathing, extreme drowsiness, severe stomach pain, vomit that looks like coffee grounds. Notes Do not share this medication with others. Laboratory and/or medical tests (such as blood counts, blood pressure, kidney/liver function tests) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Non-drug treatment for arthritis that is approved by your doctor (such as weight loss if needed, strengthening and conditioning exercises) may help improve your flexibility, range of motion, and joint function. Consult your doctor for more information. ------------------------------------------------ 产地国家: 澳大利亚 原产地英文商品名: Metacam Chewable Tablets 2.5mg/tab 84Tabs/box  原产地英文药品名: MELOXICAM 中文参考商品译名: Metacam咀嚼片 2.5毫克/瓶 84片/盒 中文参考药品译名: 美洛昔康 中文参考化合物名称: 4-羟基-2-甲基-N-(5-甲基-1,3-噻唑-2-基)-2H-1,2-苯并噻嗪-3-羧酸乙酯 1,1-二氧化物 生产厂家中文参考译名: 勃林格殷格翰 生产厂家英文名: BOEHRINGER INGELHEIM pty Ltd ------------------------------------------------ 产地国家: 澳大利亚 原产地英文商品名: METACAM INJ 5MG/ML 10ML/VIAL 原产地英文药品名: MELOXICAM 中文参考商品译名: METACAM注射剂 5毫克/毫升 10毫升/瓶 中文参考药品译名: 美洛昔康 中文参考化合物名称: 4-羟基-2-甲基-N-(5-甲基-1,3-噻唑-2-基)-2H-1,2-苯并噻嗪-3-羧酸乙酯 1,1-二氧化物 生产厂家中文参考译名: 勃林格殷格翰 生产厂家英文名: BOEHRINGER INGELHEIM ------------------------------------------------ 产地国家: 澳大利亚 原产地英文商品名: METACAM INJ 5mg/ml 20ml/vial 原产地英文药品名: MELOXICAM 中文参考商品译名: METACAM注射剂 5毫克/毫升 20毫升/瓶 中文参考药品译名: 美洛昔康 中文参考化合物名称: 4-羟基-2-甲基-N-(5-甲基-1,3-噻唑-2-基)-2H-1,2-苯并噻嗪-3-羧酸乙酯 1,1-二氧化物 生产厂家中文参考译名: 勃林格殷格翰 生产厂家英文名: BOEHRINGER INGELHEIM