英文药名：SERMION Powder（Nicergoline） 中文药名：尼麦角林散剂 日文药名：サアミオン散1％ 生产厂家：田边三菱 类别名称 脑循环和代谢改善剂 商標名 SERMION Powder 1％ 一般名 ニセルゴリン（Nicergoline） 化学名 [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl 5-bromopyridine-3-carboxylate 性状 ・白色 - 是淡黄色的结晶或结晶性粉末。 ・乙腈，乙醇（99.5），或微溶于乙酸酐，和几乎不溶于水。 ・它由轻逐渐淡棕色 組成 成分・含量 日局　ニセルゴリン　 添加物 ケイ酸アルミニウム、酢酸ビニル樹脂、酸化チタン、ステアリン酸カルシウム、タルク、乳糖水和物、ヒドロキシプロピルセルロース、ヒプロメロース、マクロゴール6000、D-マンニトール 構造式   分子式 C24H26BrN3O3 分子量 484.39 ・融点：136℃（分解）。 适应症 改善脑梗塞后遗症伴慢性循环障碍 用法用量 成人每日口服剂量三次，每次为5mg次。此外，增加或减少取决于患者的年龄和症状。 包装规格 サアミオン散1％：300g（0.5g×600包）， サアミオン散1％：100g， サアミオン散1％：500g   制造厂商 田边三菱制药株式会社 http://www.info.pmda.go.jp/go/pack/2190021B1095_1_06/ http://www.kegg.jp/medicus-bin/japic_med?japic_code=00051505 Brand name : SERMION Powder 1% 　Active ingredient: Nicergoline 　Dosage form: white powder 　Print on wrapping: サアミオン散1%, Sermion, 0.5g, TA504 Effects of this medicine This medicine increases cerebral bood flow, improves cerebral energy metabolism, and inhibit platelet aggregation. These actions improve cerebral circulation and metabolism. It is usually used to improve avolition caused by chronic cerebrovascular disorder associated with cerebral infarction sequelae. Before using this medicine, be sure to tell your doctor and pharmacist •If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If you are suspected that the haemostasis of intracranial haemorrhage has not been established. •If you are pregnant or breastfeeding. •If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.) Dosing schedule (How to take this medicine) •Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>> •In general, for adults, take 1 sachet or 0.5g (5 mg of the active ingredient) at a time, 3 times a day. It shoud be adjusted according to your age and symptoms. Strictly follow the instructions. •If you miss a dose, take a dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time. •If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist. •Do not stop taking this medicine unless your doctor instructs you to do so. Precautions while taking this medicine • Possible adverse reactions to this medicine The most commonly reported adverse reactions include nausea, rash, headache, loss of appetite, diarrhea, constipation and abdominal pain. If any of these symptoms occur, consult with your doctor or pharmacist. The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. No pertinent entries. The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. Storage conditions and other information •Keep out of the reach of children. Store away from light, heat and moisture. •Discard the remainder. Do not store them. Mitsubishi Tanabe Pharma CorporationInternal Revised: 2/2014 The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.