部分中文氯化钾处方资料（仅供参考） 药理毒理 氯化钾是一种电解质补充药物。钾是细胞内的主要阳离子，是维持细胞内渗透压的重要成分。在细胞内浓度约为150～160mmol/L，在细胞外液浓度较低，仅为3.5～5.0mmol/L。机体主要依靠细胞膜上的Na+、K+及ATP酶来维持细胞内外的K+、Na+浓度差。体内的酸碱平衡状态对钾的代谢有影响，如酸中毒时H+进入细胞内，为了维持细胞内外的电位差，K+释放到细胞外，引起或加重高钾血症。正常的细胞内外钾离子浓度及浓度差与细胞的某些功能有着密切的关系，钾参与酸碱平衡的调节，糖、蛋白质的合成以及二磷酸腺苷转化为三磷酸苷需要一定量的钾参与；钾参与神经及其支配器官间、神经元间的兴奋过程，并参与神经末梢递质(乙酰胆碱)的形成；心脏内钾的含量可影响其活动，低钾时心脏兴奋性增高，临床血钾过低的患者以心律失常为主；钾是维持骨骼肌正常张力所必需的离子。钾离子不足则表现为肌无力，抽搐。 药代动力学 氯化钾口服后可迅速被胃肠道吸收。钾90%从肾脏排泄，10%随粪便排出。 适应症 1．治疗低钾血症 各种原因引起的低钾血症，如进食不足、呕吐、严重腹泻、应用排钾性利尿药、低钾性家族周期性麻痹、长期应用糖皮质激素和补充高渗葡萄糖等。 2．预防低钾血症 当患者存在失钾情况，尤其是如果发生低钾血症对患者危害较大时(如使用洋地黄药物的患者)，需预防性补充钾盐，如进食很少、严重或慢性腹泻、长期服用肾上腺皮质激素、失钾性肾病、Bartter综合征等。 3．洋地黄中毒引起频发性、多源性早搏或快速心律失常。 用法用量 口服钾盐用于治疗轻型低钾血症或预防性用药。常规剂量成人每次0.5～1g(6.7～13.4mmol)，每日2～4次，饭后服用，并按病情调整剂量。一般成人每日最大剂量为6g(80mmol)。谨遵医嘱！ 不良反应 1．口服可有胃肠道刺激症状，如恶心、呕吐、咽部不适、胸痛(食道刺激)，腹痛、腹泻、甚至消化性溃疡及出血。在空腹、剂量较大及原有胃肠道疾病者更易发生。 2．原有肾功能损害时应注意发生高钾血症。 禁忌 1．高钾血症患者。 2．急性肾功能不全、慢性肾功能不全者。 注意事项 1．下列情况慎用： (1)急性脱水，因严重时可致尿量减少，尿K+排泄减少； (2)家族性周期性麻痹，低钾性麻痹应给予补钾，但需鉴别高钾性或正常性周期麻痹； (3)慢性或严重腹泻可致低钾血症，但同时可致脱水和低钠血症，引起肾前性少尿； (4)传导阻滞性心律失常，尤其应用洋地黄类药物时； (5)大面积烧伤、肌肉创伤、严重感染、大手术后24小时和严重溶血，上述情况本身可引起高血钾症； (6)肾上腺性异常综合征伴盐皮质激素分泌不足； (7)接受留钾利尿剂的病人。 2．用药期间需作以下随访检查： (1)血钾； (2)心电图； (3)血镁、钠、钙； (4)酸碱平衡指标；肾功能和尿量； 3．服用普通片剂及糖衣片时，对胃肠道有强烈的刺激作用，所以最好溶解成溶液后服用。 老年患者用药 老年人肾脏清除K+功能下降，应用钾盐时较易发生高钾血症。 药物相互作用 1.肾上腺糖皮质激素尤其是具有较明显盐皮质激素作用者、肾上腺盐皮质激素和促肾上腺皮质激素(ACTH)，因能促进尿钾排泄，合用时降低钾盐疗效。 2.抗胆碱能药物能加重口服钾盐尤其是氯化钾的胃肠道刺激作用。 3.非甾体类抗炎镇痛药加重口服钾盐的胃肠道反应。 4.合用库存血(库存10日以下含钾30mmol/l，库存10日以上含钾65mmol/l)、含钾药物和保钾利尿剂时，发生高钾血症的机会增多，尤其是有肾功能损害者。 5.血管紧张素转换酶抑制剂和环孢素A能抑制醛固酮分泌，尿钾排泄减少，故合用时易发生高钾血症。 6.肝素能抑制醛固酮的合成，尿钾排泄减少，合用时易发生高钾血症。另外，肝素可使胃肠道出血机会增多。 7.缓释型钾盐能抑制肠道对维生素B12的吸收。 药物过量 引起高钾血症。 Klor-Con M(POTASSIUM CHLORIDE) Generic Name: potassium chloride Dosage Form: tablet, extended release KLOR-CON® M (Potassium Chloride Extended-release Tablets, USP) 10 mEq, 15 mEq and 20 mEq MICRO-DISPERSIBLE TECHNOLOGY® Rx only Klor-Con M Description Klor-Con® M20 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet. Klor-Con® M15 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1125 mg of microencapsulated potassium chloride, USP equivalent to 15 mEq of potassium in a tablet. Klor-Con® M10 is an immediately dispersing extended-release oral dosage form of potassium chloride containing 750 mg of microencapsulated potassium chloride, USP equivalent to 10 mEq of potassium in a tablet. These formulations are intended to slow the release of potassium so that the likelihood of a high localized concentration of potassium chloride within the gastrointestinal tract is reduced. Klor-Con® M is an electrolyte replenisher. The chemical name of the active ingredient is potassium chloride, and the structural formula is KCl. Potassium chloride, USP occurs as a white, granular powder or as colorless crystals. It is odorless and has a saline taste. Its solutions are neutral to litmus. It is freely soluble in water and insoluble in alcohol. Klor-Con® M is a tablet formulation (not enteric coated or wax matrix) containing individually microencapsulated potassium chloride crystals which disperse upon tablet disintegration. In simulated gastric fluid at 37°C and in the absence of outside agitation, Klor-Con® M begins disintegrating into microencapsulated crystals within seconds and completely disintegrates within one minute. The microencapsulated crystals are formulated to provide an extended release of potassium chloride. Inactive Ingredients: croscarmellose sodium, ethylcellulose and microcrystalline cellulose. Klor-Con M - Clinical Pharmacology The potassium ion is the principal intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity; the transmission of nerve impulses; the contraction of cardiac, skeletal, and smooth muscle; and the maintenance of normal renal function. The intracellular concentration of potassium is approximately 150 to 160 mEq per liter. The normal adult plasma concentration is 3.5 to 5 mEq per liter. An active ion transport system maintains this gradient across the plasma membrane. Potassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. The usual dietary intake of potassium is 50 to 100 mEq per day. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Such depletion usually develops as a consequence of therapy with diuretics, primary or secondary hyperaldosteronism, diabetic ketoacidosis or inadequate replacement of potassium in patients on prolonged parenteral nutrition. Depletion can develop rapidly with severe diarrhea, especially if associated with vomiting. Potassium depletion due to these causes is usually accompanied by a concomitant loss of chloride and is manifested by hypokalemia and metabolic alkalosis. Potassium depletion may produce weakness, fatigue, disturbances or cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine. If potassium depletion associated with metabolic alkalosis cannot be managed by correcting the fundamental cause of the deficiency, e.g., where the patient requires long-term diuretic therapy, supplemental potassium in the form of high-potassium food or potassium chloride may be able to restore normal potassium levels. In rare circumstances (e.g., patients with renal tubular acidosis) potassium depletion may be associated with metabolic acidosis and hyperchloremia. In such patients potassium replacement should be accomplished with potassium salts other than the chloride, such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate. Indications and Usage for Klor-Con M BECAUSE OF REPORTS OF INTESTINAL AND GASTRIC ULCERATION AND BLEEDING WITH EXTENDED-RELEASE POTASSIUM CHLORIDE PREPARATIONS, THESE DRUGS SHOULD BE RESERVED FOR THOSE PATIENTS WHO CANNOT TOLERATE OR REFUSE TO TAKE LIQUID OR EFFERVESCENT POTASSIUM PREPARATIONS OR FOR PATIENTS IN WHOM THERE IS A PROBLEM OF COMPLIANCE WITH THESE PREPARATIONS. For the treatment of patients with hypokalemia with or without metabolic alkalosis, in digitalis intoxication and in patients with hypokalemic familial periodic paralysis. If hypokalemia is the result of diuretic therapy, consideration should be given to the use of a lower dose of diuretic, which may be sufficient without leading to hypokalemia. For the prevention of hypokalemia in patients who would be at particular risk if hypokalemia were to develop, e.g., digitalized patients or patients with significant cardiac arrhythmias. The use of potassium salts in patients receiving diuretics for uncomplicated essential hypertension is often unnecessary when such patients have a normal dietary pattern and when low doses of the diuretic are used. Serum potassium should be checked periodically, however, and if hypokalemia occurs, dietary supplementation with potassium-containing foods may be adequate to control milder cases. In more severe cases, and if dose adjustment of the diuretic is ineffective or unwarranted, supplementation with potassium salts may be indicated. Contraindications Potassium supplements are contraindicated in patients with hyperkalemia since a further increase in serum potassium concentration in such patients can produce cardiac arrest. Hyperkalemia may complicate any of the following conditions: chronic renal failure, systemic acidosis, such as diabetic acidosis, acute dehydration, extensive tissue breakdown as in severe burns, adrenal insufficiency, or the administration of a potassium-sparing diuretic (e.g., spironolactone, triamterene, or amiloride) (see OVERDOSAGE). Extended-release formulations of potassium chloride have produced esophageal ulceration in certain cardiac patients with esophageal compression due to enlarged left atrium. Potassium supplementation, when indicated in such patients, should be given as a liquid preparation or as an aqueous (water) suspension of Klor-Con® M (see PRECAUTIONS: Information for Patients and DOSAGE AND ADMINISTRATION sections). All solid oral dosage forms of potassium chloride are contraindicated in any patient in whom there is structural, pathological (e.g., diabetic gastroparesis), or pharmacologic (use of anticholinergic agents or other agents with anticholinergic properties at sufficient doses to exert anticholinergic effects) cause for arrest or delay in tablet passage through the gastrointestinal tract. Warnings Hyperkalemia (see OVERDOSAGE)—In patients with impaired mechanisms for excreting potassium, the administration of potassium salts can produce hyperkalemia and cardiac arrest. This occurs most commonly in patients given potassium by the intravenous route but may also occur in patients given potassium orally. Potentially fatal hyperkalemia can develop rapidly and be asymptomatic. The use of potassium salts in patients with chronic renal disease, or any other condition which impairs potassium excretion, requires particularly careful monitoring of the serum potassium concentration and appropriate dosage adjustment. Interaction with Potassium–Sparing Diuretics—Hypokalemia should not be treated by the concomitant administration of potassium salts and a potassium-sparing diuretic (e.g., spironolactone, triamterene, or amiloride) since the simultaneous administration of these agents can produce severe hyperkalemia. Interaction with Angiotensin-Converting Enzyme Inhibitors—Angiotensin-converting enzyme (ACE) inhibitors (e.g., captopril, enalapril) will produce some potassium retention by inhibiting aldosterone production. Potassium supplements should be given to patients receiving ACE inhibitors only with close monitoring. Gastrointestinal Lesions—Solid oral dosage forms of potassium chloride can produce ulcerative and/or stenotic lesions of the gastrointestinal tract. Based on spontaneous adverse reaction reports, enteric-coated preparations of potassium chloride are associated with an increased frequency of small bowel lesions (40-50 per 100,000 patient years) compared to extended-release wax matrix formulations (less than one per 100,000 patient years). Because of the lack of extensive marketing experience with microencapsulated products, a comparison between such products and wax matrix or enteric-coated products is not available. Klor-Con® M is a tablet formulated to provide an extended rate of release of microencapsulated potassium chloride and thus to minimize the possibility of a high local concentration of potassium near the gastrointestinal wall. Prospective trials have been conducted in normal human volunteers in which the upper gastrointestinal tract was evaluated by endoscopic inspection before and after one week of solid oral potassium chloride therapy. The ability of this model to predict events occurring in usual clinical practice is unknown. Trials which approximated usual clinical practice did not reveal any clear differences between the wax matrix and microencapsulated dosage forms. In contrast, there was a higher incidence of gastric and duodenal lesions in subjects receiving a high dose of a wax matrix extended-release formulation under conditions which did not resemble usual or recommended clinical practice (i.e., 96 mEq per day in divided doses of potassium chloride administered to fasted patients, in the presence of an anticholinergic drug to delay gastric emptying). The upper gastrointestinal lesions observed by endoscopy were asymptomatic and were not accompanied by evidence of bleeding (Hemoccult testing). The relevance of these findings to the usual conditions (i.e., non-fasting, no anticholinergic agent, smaller doses) under which extended-release potassium chloride products are used is uncertain; epidemiologic studies have not identified an elevated risk, compared to microencapsulated products, for upper gastrointestinal lesions in patients receiving wax matrix formulations. Klor-Con® M should be discontinued immediately and the possibility of ulceration, obstruction, or perforation should be considered if severe vomiting, abdominal pain, distention, or gastrointestinal bleeding occurs. Metabolic Acidosis—Hypokalemia in patients with metabolic acidosis should be treated with an alkalinizing potassium salt such as potassium bicarbonate, potassium citrate, potassium acetate or potassium gluconate. Precautions General: The diagnosis of potassium depletion is ordinarily made by demonstrating hypokalemia in a patient with a clinical history suggesting some cause for potassium depletion. In interpreting the serum potassium level, the physician should bear in mind that acute alkalosis per se can produce hypokalemia in the absence of a deficit in total body potassium while acute acidosis per se can increase the serum potassium concentration into the normal range even in the presence of a reduced total body potassium. The treatment of potassium depletion, particularly in the presence of cardiac disease, renal disease, or acidosis requires careful attention to acid-base balance and appropriate monitoring of serum electrolytes, the electrocardiogram, and the clinical status of the patient. Information for Patients: Physicians should consider reminding the patient of the following: To take each dose with meals and with a full glass of water or other liquid. To take each dose without crushing, chewing or sucking the tablets. If those patients are having difficulty swallowing whole tablets, they may try one of the following alternate methods of administration: Break the tablet in half, and take each half separately with a glass of water. Prepare an aqueous (water) suspension as follows: Place the whole tablet(s) in approximately one-half glass of water (4 fluid ounces). Allow approximately 2 minutes for the tablet(s) to disintegrate. Stir for about half a minute after the tablet(s) has disintegrated. Swirl the suspension and consume the entire contents of the glass immediately by drinking or by the use of a straw. Add another one fluid ounce of water, swirl, and consume immediately. Then, add an additional one fluid ounce of water, swirl, and consume immediately. Aqueous suspension of Klor-Con® M extended-release tablet that is not taken immediately should be discarded. The use of other liquids for suspending Klor-Con® M tablets is not recommended. To take this medicine following the frequency and amount prescribed by the physician. This is especially important if the patient is also taking diuretics and/or digitalis preparations. To check with the physician at once if tarry stools or other evidence of gastrointestinal bleeding is noticed. Laboratory Tests: When blood is drawn for analysis of plasma potassium it is important to recognize that artifactual elevations can occur after improper venipuncture technique or as a result of in-vitro hemolysis of the sample. Drug Interactions: Potassium-sparing diuretics, angiotensin-converting enzyme inhibitors (see WARNINGS). Carcinogenesis, Mutagenesis, Impairment of Fertility: Carcinogenicity, mutagenicity, and fertility studies in animals have not been performed. Potassium is a normal dietary constituent. Pregnancy Category C: Animal reproduction studies have not been conducted with Klor-Con® M. It is unlikely that potassium supplementation that does not lead to hyperkalemia would have an adverse effect on the fetus or would affect reproductive capacity. Nursing Mothers: The normal potassium ion content of human milk is about 13 mEq per liter. Since oral potassium becomes part of the body potassium pool, so long as body potassium is not excessive, the contribution of potassium chloride supplementation should have little or no effect on the level in human milk. Pediatric Use: Safety and effectiveness in pediatric patients have not been established. Geriatric Use: Clinical studies of potassium chloride did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection; and it may be useful to monitor renal function. Adverse Reactions One of the most severe adverse effects is hyperkalemia (see CONTRAINDICATIONS, WARNINGS and OVERDOSAGE). There have also been reports of upper and lower gastrointestinal conditions including obstruction, bleeding, ulceration, and perforation (see CONTRAINDICATIONS and WARNINGS). The most common adverse reactions to oral potassium salts are nausea, vomiting, flatulence, abdominal pain/discomfort, and diarrhea. These symptoms are due to irritation of the gastrointestinal tract and are best managed by diluting the preparation further, taking the dose with meals or reducing the amount taken at one time. Overdosage The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired or if potassium is administered too rapidly intravenously, potentially fatal hyperkalemia can result (see CONTRAINDICATIONS and WARNINGS). It is important to recognize that hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5-8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-waves, depression of S-T segment, and prolongation of the QT-interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9-12 mEq/L). Treatment measures for hyperkalemia include the following: Patients should be closely monitored for arrythmias and electrolyte changes. Elimination of foods and medications containing potassium and of any agents with potassium-sparing properties such as potassium-sparing diuretics, ARBS, ACE inhibitors, NSAIDs, certain nutritional supplements and many others. Intravenous calcium gluconate if the patient is at no risk or low risk of developing digitalis toxicity. Intravenous administration of 300 to 500 mL/hr of 10% dextrose solution containing 10-20 units of crystalline insulin per 1,000 mL. Correction of acidosis, if present, with intravenous sodium bicarbonate. Use of exchange resins, hemodialysis, or peritoneal dialysis. In treating hyperkalemia, it should be recalled that in patients who have been stabilized on digitalis, too rapid a lowering of the serum potassium concentration can produce digitalis toxicity. The extended release feature means that absorption and toxic effects may be delayed for hours. Consider standard measures to remove any unabsorbed drug. Klor-Con M Dosage and Administration The usual dietary intake of potassium by the average adult is 50 to 100 mEq per day. Potassium depletion sufficient to cause hypokalemia usually requires the loss of 200 or more mEq of potassium from the total body store. Dosage must be adjusted to the individual needs of each patient. The dose for the prevention of hypokalemia is typically in the range of 20 mEq per day. Doses of 40-100 mEq per day or more are used for the treatment of potassium depletion. Dosage should be divided if more than 20 mEq per day is given such that no more than 20 mEq is given in a single dose. Each Klor-Con® M20 tablet provides 1500 mg of potassium chloride equivalent to 20 mEq of potassium. Each Klor-Con® M15 tablet provides 1125 mg of potassium chloride equivalent to 15 mEq of potassium. Each Klor-Con® M10 tablet provides 750 mg of potassium chloride equivalent to 10 mEq of potassium. Klor-Con® M tablets should be taken with meals and with a glass of water or other liquid. This product should not be taken on an empty stomach because of its potential for gastric irritation (see WARNINGS). Patients having difficulty swallowing whole tablets may try one of the following alternate methods of administration: Break the tablet in half and take each half separately with a glass of water. Prepare an aqueous (water) suspension as follows: Place the whole tablet(s) in approximately one-half glass of water (4 fluid ounces). Allow approximately 2 minutes for the tablet(s) to disintegrate. Stir for about half a minute after the tablet(s) has disintegrated. Swirl the suspension and consume the entire contents of the glass immediately by drinking or by the use of a straw. Add another one fluid ounce of water, swirl, and consume immediately. Then, add an additional one fluid ounce of water, swirl, and consume immediately. Aqueous suspension of Klor-Con® M extended-release tablet that is not taken immediately should be discarded. The use of other liquids for suspending Klor-Con® M tablets is not recommended. How is Klor-Con M Supplied Klor-Con® M20 Extended-release Tablets, 1500 mg of potassium chloride (20 mEq of potassium) are available in bottles of 90 (NDC 0245-0058-90); bottles of 100 (NDC 0245-0058-11); bottles of 500 (NDC 0245-0058-15); bottles of 1000 (NDC 0245-0058-10); and cartons of 100 for unit dose dispensing (NDC 0245-0058-01). Klor-Con® M20 tablets are white, oblong, imprinted KC M20 and scored for flexibility of dosing. Klor-Con® M15 Extended-release Tablets, 1125 mg of potassium chloride (15 mEq of potassium) are available in bottles of 100 (NDC 0245-0150-11); bottles of 1000 (NDC 0245-0150-10); and cartons of 100 for unit dose dispensing (NDC 0245-0150-01). Klor-Con® M15 tablets are white, oblong, imprinted M 15 and scored for flexibility of dosing. Klor-Con® M10 Extended-release Tablets, 750 mg of potassium chloride (10 mEq of potassium) are available in bottles of 90 (NDC 0245-0057-90); bottles of 100 (NDC 0245-0057-11); bottles of 1000 (NDC 0245-0057-10); and cartons of 100 for unit dose dispensing (NDC 0245-0057-01). Klor-Con® M10 tablets are white, oblong and imprinted KC M10. Keep tightly closed. Store at 20-25°C (68-77°F). Excursions permitted to 15-30°C (59-86°F). [See USP Controlled Room Temperature.] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b8552fd0-1c4f-4dcc-bfc8-2e04b0a64c59 ------------------------------------------------------------ 注：以下产品不同规格和不同价格，购买时请以咨询为准！ ------------------------------------------------------------- 产地国家: 美国 原产地英文商品名: KLOR-CON M10 SR TAB 100MEQ/TAB 100TABS/BOTTLE 原产地英文药品名: POTASSIUM CHLORIDE 中文参考商品译名: KLOR-CON M10缓释片 10毫当量/片 100片/瓶 中文参考药品译名: 氯化钾 生产厂家中文参考译名: UPSHER SMITH 生产厂家英文名: UPSHER SMITH ------------------------------------------------------------- 产地国家: 美国 原产地英文商品名: KLOR-CON M20 SR TAB 20MEQ/TAB 100TABS/BOTTLE 原产地英文药品名: POTASSIUM CHLORIDE 中文参考商品译名: KLOR-CON M20缓释片 20毫当量/片 100片/瓶 中文参考药品译名: 氯化钾 生产厂家中文参考译名: UPSHER SMITH 生产厂家英文名: UPSHER SMITH ------------------------------------------------------------- 原产地英文商品名: KLOR-CON SLOW RELEASE TAB 8MEQ/TAB 100TABS/BOTTLE 原产地英文药品名: POTASSIUM CHLORIDE 中文参考商品译名: KLOR-CON缓释片 8毫当量/片 100片/瓶 中文参考药品译名: 氯化钾 生产厂家中文参考译名: UPSHER SMITH 生产厂家英文名: UPSHER SMITH ------------------------------------------------------------- 原产地英文商品名: KLOR-CON SLOW RELEASE TAB 10MEQ/TAB 100TABS/BOTTLE 原产地英文药品名: POTASSIUM CHLORIDE 中文参考商品译名: KLOR-CON缓释片 10毫当量/片 100片/瓶 中文参考药品译名: 氯化钾 生产厂家中文参考译名: UPSHER SMITH 生产厂家英文名: UPSHER SMITH