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萘普生缓释片EC-NAPROSYN DR（NAPROXEN）

2013-03-17 00:27:23 作者：新特药房来源：互联网浏览次数：193 文字大小：【大】【中】【小】

简介： 中文药名: 萘普生钠片药效类别: 消炎镇痛药通用药名: NAPROXEN SODIUM别　　名: Aleve, Anaprox, Antalgin, Apranax, Apronax, Danaprox, Femex, Flanax, Naprogesic, Naprosian, Naprosyn, Naxen, Nyc ...

关键字：萘普生缓释片EC-NAPROSYN DR 关节炎镇痛

中文药名: 萘普生钠片
药效类别: 消炎镇痛药
通用药名: NAPROXEN SODIUM
别　　名: Aleve, Anaprox, Antalgin, Apranax, Apronax, Danaprox, Femex, Flanax, Naprogesic, Naprosian, Naprosyn, Naxen, Nycopren, Synflex
化学名称: 2-Naphthalenacetic acid, 6-methoxy-α-methyl-, sodium salt
性状:
萘普生是一种2-芳基丙酸类（布洛芬）的非甾体抗炎药。白色或类白色结晶性粉末，几乎无臭。可在脂类物质中溶解，在水中几乎不溶。它的熔点是153°C。
适应症
对类风湿性关节炎、骨关节炎、强直性脊椎炎、痛风、运动系统（如关节、肌肉及腱）的慢性变性疾病及轻、中度疼痛如痛经等，均有肯定疗效。
用法用量
口服：开始每日剂量５００～７５０ｍｇ，维持量每日３７５～７５０ｍｇ，分早晨及傍晚２次服用。轻、中度疼痛或痛经时，开始用５００ｍｇ，必需时经６～８小时后再服２５０ｍｇ，日剂量不得超过１２５０ｍｇ。
任何疑问，请遵医嘱！
副作用与警告
正如其他非甾体抗炎药一样，萘普生可以抑制钠和锂的代谢。服用该药的同时服用锂补剂时必须十分注意。萘普生等非甾体抗炎药也不应与水杨酸类药物(如阿司匹林) (因为药物会降低彼此疗效)或者与抗凝血剂(会增加出血的风险)一起服用。萘普生钠药物不能让钠敏高血压患者服用，因为这会给患者带来潜在的发病危险。
2006年8月，Birth DefectsResearch杂志B刊[2]刊登了三个月孕龄内的孕妇服用了包括萘普生在内的非甾体抗炎药的研究结果，结果表明该类药物会增加胎儿先天缺陷的可能性，特别是先天心血管病。
注意事项
1.长期服用耐受良好，不良反应主要为胃肠道轻度和暂时不适。偶有恶心、呕吐、消化不良、便秘、胃肠道出血、失眠或嗜睡、头痛、头晕、耳鸣、瘙痒、皮疹、血管神经性水肿、视觉障碍及出血时间延长，一般不需中断治疗。
2.与乙酰水杨酸等非甾体抗炎药有交叉过敏反应，禁用于对本品及对乙酰水杨酸过敏的病人。
3.对伴有消化性溃疡或有消化性溃疡病史者慎用；对有活动性胃及十二指肠溃疡病人应在严格监督下使用。
4.本品可加强双香豆素的抗凝血作用。
5.与丙磺舒合用时，可增加本品的血药水平及明显延长本品的血药半衰期。
规格
片剂：每片２75ｍｇ。
Anaprox
Generic Name: Naproxen
What is Anaprox?
Anaprox is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, swelling, and inflammation from medical conditions such as arthritis, tendonitis, acute gout,
menstrual cramps, ankylosing spondylitis, and bursitis.
What is the most important information I should know about Anaprox?
NSAIDs may increase the risk of a heart attack or stroke, which can lead to death. This risk increases with longer use of NSAIDs and in people with heart disease.
NSAIDs should never be used right before or after a type of heart surgery called a coronary artery bypass graft (CABG).
NSAIDs can cause ulcers and bleeding in the stomach and intestines at any time during treatment, which can lead to death. Elderly patients are at greater risk for this
complication.
NSAIDs can cause hypertension or worsening of existing hypertension.
NSAIDs should only be used exactly as prescribed, at the lowest dose appropriate for your condition, and for the shortest time needed.
Who should not take Anaprox?
If you had an asthma attack, hives, or other allergic reactions while taking aspirin or any other NSAIDs, you should not take this medication. NSAIDs should not be used for pain right before or after heart bypass surgery.
What should I tell my doctor before I take the first dose of Anaprox?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Anaprox. Talk to your doctor about your complete medical history, especially if you have asthma or if you are pregnant or breastfeeding. You should also notify your doctor if you smoke, use alcohol, have liver or kidney dysfunction, heart failure, or if you have had a serious reaction to aspirin or other NSAIDs in the past.
What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Acute Gout
Adults: The recommended starting dose is 825 milligrams (mg)of Anaprox followed by 275 mg every 8 hours until the attack has subsided.
Management of Pain, Menstrual Cramps, and Acute Tendonitis and Bursitis
Adults: The recommended starting dose is 550 mg of Anaprox followed by 550 mg every 12 hours or 275 mg every 6 to 8 hours as required.
Rheumatoid Arthritis, Osteoarthritis, and Ankylosing
Spondylitis
Adults: The usual dose of Anaprox is 275 mg twice daily.
How should I take Anaprox?
To avoid upset stomach, you may take Anaprox with food and with a full glass of water.
What should I avoid while taking Anaprox?
Avoid taking antacids, aspirin, or other NSAIDs while taking Anaprox. Avoid all alcohol while taking Anaprox.
What are possible food and drug interactions associated with Anaprox?
If Anaprox is taken with certain other drugs, the effects of either could be increased, decreased, or altered.
It is especially important to check with your doctor before combining Anaprox with the following: ACE inhibitors, antacids and sucralfate, aspirin, beta-blockers (such as propranolol), cholestyramine, coumarin-type anticoagulants, diuretics such as furosemide and thiazides, hydantoins, lithium, methotrexate, NSAIDs, probenecid, antidepressant medications known as SSRIs, sulfonamides, sulfonylureas, and warfarin.
What are the possible side effects of Anaprox?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Serious side effects may include: heart attack, stroke, high blood pressure, heart failure from body swelling (fluid retention), kidney problems including kidney failure, bleeding and ulcers in the stomach and intestine, low red blood cells(anemia), life-threatening skin reactions, life-threatening allergic reactions, liver problems including liver failure, asthma attacks in people with asthma
Other side effects may include: stomach pain, constipation, diarrhea, gas, heartburn, nausea, vomiting, dizzinessGet immediate medical attention if you experience: shortness
of breath or trouble breathing, chest pain, weakness in one part or side of your body, slurred speech, swelling of the face or throat, nausea, fatigue or weakness, itching,
yellowing of your skin or eyes, stomach pain, flulike symptoms, blood in your vomit, blood in your bowel movement(or if it is black and sticky like tar), unusual weight gain, skin rash or blistering with fever, swelling of the arms, legs, hands, and feet
Can I receive Anaprox if I am pregnant or breastfeeding?
Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding. Anaprox, like all NSAIDs, should be avoided during pregnancy, particularly in late pregnancy. Anaprox should not be used if breastfeeding.
What should I do if I miss a dose of Anaprox?
If you miss a dose of Anaprox, take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular
dosing schedule. Do not double the dose. If you are unsure, ask your doctor or pharmacist for advice.
How should I store Anaprox?
Store Anaprox at room temperature in a well-closed container.
附件:

201261123511310.PDF

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产地国家: 美国
原产地英文商品名:
EC-NAPROSYN DR TAB 375MG/TAB 100TABS/BOTTLE
原产地英文药品名:
NAPROXEN
原产地英文化合物名称:
2-Naphthalenacetic acid, 6-methoxy-α-methyl-, sodium salt
中文参考商品译名:
EC-NAPROSYN缓释片 375毫克/片 100片/瓶
中文参考药品译名:
萘普生
生产厂家中文参考译名:
罗氏
生产厂家英文名:
ROCHE PALO