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英文药名：VALRAIZER Ophthalmic Solution 0.1%（Pranoprofen）
中文药名：普拉洛芬点眼液
生产厂家：三和化学研究所
治疗类别名称
非甾体抗炎滴眼液
欧洲商标名
VALRAIZER Ophthalmic Solution 0.1%
一般名
プラノプロフェン（Pranoprofen）
化学名
（2ＲＳ）-2-(10Ｈ-9-Oxa-1-azaanthracen-6-yl)propanoic acid
分子式
Ｃ15Ｈ13ＮＯ3分子量
255.27
構造式
性 状
本产品是白色结晶粉末，以淡黄白色。 N，N-二甲基甲酰胺和溶于乙酸（100）很容易微溶，稍少溶于甲醇，乙腈，乙醇（95）或微溶于乙酸酐，和极微溶于乙醚，和几乎不溶于水。
N的产物N-二甲基甲酰胺溶液（1→30）示出了没有旋光性。
融 点
186〜190℃
药理作用
本品系丙酸衍生物，为非甾体类抗炎镇痛药，主要能抑制前列腺素的生物合成而发挥解热、镇痛、抗炎作用。本品对家兔发热的抑制作用比吲哚美辛、布洛芬、阿司匹林更强，而对正常体温几乎没有任何影响；在脂多糖(LPS)引起家兔发热的实验中，使用糖浆剂进行口服给药，其解热作用呈剂量依赖性。此外，动物实验还表明，本品的镇痛作用较布洛芬及阿司匹林强。
适应症
外眼及眼前部的对症治疗（眼睑炎、结膜炎、角膜炎、巩膜炎、浅层巩膜炎、虹膜睫状体炎、术后炎症）。
滴眼：每次1～2滴，每日4次。根据症状可以适当增减次数
包装规格
5ml*1瓶
生产商
三和化学研究所[首发公司］武田制药股份有限公司
VALRAIZER Ophthalmic Solution 0.1%（バルライザー点眼液0.1%）
Brand name : VALRAIZER Ophthalmic Solution 0.1%
Active ingredient: Pranoprofen
Dosage form: limpid and clear ophthalmic solution
Print on wrapping: バルライザー点眼液0.1％
Effects of this medicine
This medicine shows anti-inflammatory effects by suppressing prostaglandin biosynthesis.
It is usually used in relieving symptoms of inflammatory diseases in external and anterior eye such as blepharitis, conjunctivitis, keratitis, and postoperative inflammation.
Before using this medicine, be sure to tell your doctor and pharmacist
If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you are wearing contact lenses.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
General dosage regimen: Apply 1-2 drops at a time, 4 times daily. The number of doses may be adjusted according to the symptoms. Strictly follow the instructions of your doctor/pharmacist.
Use a dose as soon as possible when you remember that you missed a dose and continue your regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT use double doses to make up for the missed dose.
If you used too much of the medicine (more than ordered), check with your doctor/pharmacist.
Do not stop using the medicine without the instructions of your doctor.
Precautions while taking this medicine
Possible adverse reactions to this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: rash, hives, contact dermatitis, irritation, conjunctival congestion, itch, redness or swelling in the eyelids, blepharitis, discharge, lacrimation, diffuse superficial keratitis, mattering of the eyelids, conjunctival edema, airway stenosis, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep out of the reach of children. Store the medicine in a shading sachet, away from heat and moisture.
Discard the remainder. Do not store them.
SANWA KAGAKU KENKYUSHO CO.,LTD. External
Revised: 1/2011
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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