繁体中文
设为首页
加入收藏
当前位置:药品说明书与价格首页 >> 耳鼻喉 >> 鼻炎 >> REMICUT CAPSULE(富马酸依美斯汀胶囊)

REMICUT CAPSULE(富马酸依美斯汀胶囊)

2016-06-11 04:22:55  作者:新特药房  来源:互联网  浏览次数:0  文字大小:【】【】【
简介: 英文药名:REMICUT CAPSULE(Emedastine Fumarate) 中文药名:富马酸依美斯汀胶囊 生产厂家:Kowa Co レミカットカプセル1mg/レミカットカプセル2mg 治疗类别名称过敏性疾病治疗药物商標名 REMICU ...

英文药名:REMICUT CAPSULE(Emedastine Fumarate)

中文药名:富马酸依美斯汀胶囊

生产厂家:Kowa Co

レミカットカプセル1mg/レミカットカプセル2mg

治疗类别名称
过敏性疾病治疗药物
商標名
REMICUT CAPSULE
一般名
エメダスチンフマル酸塩(Emedastine Fumarate)(JAN)
化学名
1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzoimidazole difumarate
分子式
C17H26N4O・2C4H4O4
分子量
534.56
構造式

性状
白色至黄精的结晶性粉末。易溶于水,略溶于甲醇,微溶于乙醇(99.5),乙酸(100)微溶。水晶多态性观察。
熔点
149〜152℃
药效药理
1. 抗过敏作用
过敏性休克和豚鼠和大鼠豚鼠被动皮肤过敏是由口服抑制。
在大鼠实验性过敏性鼻炎是由口服抑制。
2. 抗组胺作用
它抑制了离体豚鼠回肠收缩反应,由于组胺(体外)。
它表现出抗组胺致死的抑制和在豚鼠(体内)血管通透性增加。
3. 通过抗原 - 抗体反应的化学介质释放的抑制动作
从大鼠腹膜肥大细胞通过抗原 - 抗体反应,以及从人外周血白细胞组胺和白三烯C4释放和肺组织中浓度依赖性方式组胺释放反应(体外)。它表明由豚鼠被动腹腔过敏性(体内)于组胺释放的抑制作用。
4. P物质对组胺释放的抑制作用
由物质P大鼠腹膜肥大细胞的组胺释放,从低浓度(体外)抑制。组胺释放的抑制作用,由钙离子对钙离子大量涌入的抑制作用释放抑制作用,并从细胞内钙储存地点细胞。
5. 嗜酸性粒细胞移动抑制和侵袭抑制作用
由PAF豚鼠嗜酸性粒细胞迁移是在上述10-9M浓度依赖的方式(体外)。PAF与白三烯B4的人的嗜酸性粒细胞迁移是由比10-8M更浓度依赖性地抑制(体外)。
在豚鼠鼻过敏模型,它抑制了嗜酸性粒细胞浸润在口服鼻粘膜。
适应病症
过敏性鼻炎,荨麻疹,湿疹,皮炎,皮肤瘙痒,痒疹
用法用量
成人,每日二次,每次口服1-2毫克,早饭前和睡前后口服。
包装规格
胶囊:1mg
PTP:100粒 500胶囊 1000胶囊 3000胶囊


胶囊:2mg
PTP:100粒 500胶囊 1000胶囊 3000胶囊


制造厂商
興和株式会社
完整处方附件:http://www.info.pmda.go.jp/go/pack/4490013M1038_1_08/
REMICUT CAPSULE 1mg(レミカットカプセル1mg)
Brand name : REMICUT CAPSULE 1mg
 Active ingredient: Emedastine fumarate
 Dosage form: white capsule, length: 14.5 mm, diameter: 5.3 mm
 Print on wrapping: レミカット1mg, 1mg, 501, REMICUT 1mg, レミカット
REMICUT CAPSULE 2mg(レミカットカプセル2mg) 
Effects of this medicine
This medicine improves allergic symptoms such as sneezing, runny nose, nasal congestion or itchy skin by its antiallergic/antihistaminic action.
It is usually used to treat allergic rhinitis, hives, eczema/dermatitis, dermal pruritus or prurigo.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, for adults, take 1 to 2 capsules (1 to 2 mg of the active ingredient) at a time, twice a day after breakfast and before bedtime. Strictly follow the instructions.
•Take this medicine without chewing as it is sustained release preparation.
•If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
•If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•This medicine may cause drowsiness. Avoid operating dangerous machinery, such as driving a car.
•Pay attention that drinking alcohol may intensify drowsiness.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include drowsiness, malaise/lassitude, dry mouth, abdominal pain, light headedness, headache/dull headache, blank feeling, rash and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.
Kowa Co., Ltd.Internal
Revised: 6/2015
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


相关文章
慢性阻塞性肺病复方新药Bevespi Aerosphere获FDA批准
NKS-1 combination capsule T20/T25(复方替加氟/吉莫斯特/氧嗪酸钾胶囊)
Dellegra combination tablet(盐酸非索非那定/盐酸伪麻黄碱配合片)
Zaditen Ophthalmic Solution UD 0.05%(富马酸酮替芬点眼液)
Viread(Tenofovir Disoproxil Fumarate Tablets/Powder)
Alecensa Capsule(Alectinib Hydrochloride)
OLOPATADINE HYDROCHLORIDE OD TABLETS(奥洛他定口腔崩解片)
Flutiform(复方丙酸氟替卡松/富马酸福莫特罗吸入剂)
Flutiform Aerosol(复方丙酸氟替卡松/富马酸福莫特罗吸入剂
OLYSIO(SIMEPREVIR SODIUM)CAPSULE ORAL
 

最新文章

更多

· REMICUT CAPSULE(富马酸...
· KIPRES OD Tablets(孟鲁...
· Allegra tablets(Fexof...
· Dellegra combination t...
· KIPRES Tablets(孟鲁司...
· KARBINAL ER(马来酸卡比...
· Nasonex Nasal(Mometas...
· Alesion Dry Syrup 1%(...
· Alesion Tablets(Epina...
· Erizas Capsule for Nas...

推荐文章

更多

· REMICUT CAPSULE(富马酸...
· KIPRES OD Tablets(孟鲁...
· Allegra tablets(Fexof...
· Dellegra combination t...
· KIPRES Tablets(孟鲁司...
· KARBINAL ER(马来酸卡比...
· Nasonex Nasal(Mometas...
· Alesion Dry Syrup 1%(...
· Alesion Tablets(Epina...
· Erizas Capsule for Nas...

热点文章

更多

· REMICUT CAPSULE(富马酸...