部份中文替考拉宁处方资料（仅供参考） 药品名称：注射用替考拉宁 英文名称：Teicoplanin 其他名称 肽可霉素，太古霉素，他格适，Techomycin，Targocid 治疗类别名称 糖肽抗生素配方 适应证 1.甲氧西林耐药金葡菌和凝固酶阴性葡萄球菌、肠球菌属等对本品敏感革兰阳性菌所致的严重感染如败血症、骨髓炎、肺炎及下呼吸道感染、皮肤软组织感染以及透析相关性腹膜炎。 2.用于青霉素过敏患者的肠球菌属或链球菌属严重感染的治疗。 3.粒细胞缺乏症患者的革兰阳性球菌感染。 不良反应 应用本品后常见的不良反应为注射部位的疼痛和皮疹等过敏反应，其次为一过性的肝、肾功能异常，少数患者可发生耳、肾毒性，偶见恶心、呕吐、眩晕、嗜酸粒细胞增多、粒细胞减少，血小板减少等。对照研究的结果显示替考拉宁引起的“红人综合征”明显较万古霉素少见，而血小板减少的发生率则在替考拉宁组较为常见，尤其常见于应用高剂量者。对照研究显示在常用剂量下替考拉宁的肾毒性较万古霉素低。本品与万古霉素有交叉过敏反应。 禁忌证 对本品过敏者禁用。也禁用于对万古霉素、去甲万古霉素等糖肽类抗生素过敏者。 注意事项 1.肾功能不全患者应用本品时，必须根据肾功能减退程度调整该药剂量。 2.用药期间需注意肾、耳毒性的发生，必须定期随访肾功能、尿常规、血常规、肝功能，注意听力改变，必要时监测听力。 3.用于重症患者剂量加大时仍需监测血药浓度。 药物相互作用 目前尚缺乏替考拉宁与其他药物同时应用发生相互作用的相关报道。静脉麻醉药成瘾患者对替考拉宁的肾清除加快，常需加大剂量。 给药说明 肾功能不全肌酐清除率为0.667～1ml/s者，替考拉宁的成人剂量为常规量的一半，而肌酐清除率低于0.667ml/s，本品的剂量不超过常规量的三分之一，但首剂饱和量均与肾功能正常者同。血液透析患者，首剂800mg，以后每周400mg；严重感染者首剂800mg，透析后第2天，3天，5天，12天和19天均给400mg维持。腹膜透析患者可在每升腹透液中加替考拉宁20mg。 用法与用量 一般感染： ①成人剂量：首剂400mg，继以每日200mg，重症感染者，成人剂量为首剂400mg，每12小时1次，共3次。继以每日400mg。 ②儿童：替考拉宁10mg/kg，每日1次；新生儿每日1次，6mg/kg。 テイコプラニン点滴静注用200mg「明治」／テイコプラニン点滴静注用400mg「明治」 TEICOPLANIN for I.V. Infusion（Teicoplanin） TEICOPLANIN for I.V. Infusion 200mg "MEIJI"（テイコプラニン点滴静注用200mg「明治」） Brand name: TEICOPLANIN for I.V. Infusion 200mg "MEIJI" 　Active ingredient: Teicoplanin 　Dosage form: Injection 　Print on wrapping: TEICOPLANIN for I.V. Infusion 400mg "MEIJI"（テイコプラニン点滴静注用400mg「明治」）  Brand name: TEICOPLANIN for I.V. Infusion 400mg "MEIJI" 　Active ingredient: Teicoplanin 　Dosage form: Injection 　Print on wrapping: Effects of this medicine This medicine is a glycopeptide antibiotic which inhibits cell wall synthesis of bacteria and shows an antibacterial effect. It is usually used to treat sepsis, deep-seated skin infection, chronic pyoderma, secondary infection in injury/burn or surgical wound, pneumonia, pyothorax and secondary infection in chronic respiratory lesion. Before using this medicine, be sure to tell your doctor and pharmacist •If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If you have: hearing difficulty, renal disorder or liver disorder. •If you are pregnant or breastfeeding. •If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.) Dosing schedule (How to take this medicine) •Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>> •In general, for adults, this medicine is administered by intravenous infusion over a period of 30 minutes or longer twice a day on Day 1. Then administered once a day. For infants and children, administered by intravenous infusion over a period of 30 minutes or longer three times at an intervals of 12 hours. Then administered at an intervals of 24 hours. For neonates (including low birth-weight baby), administered by intravenous infusion over a period of 30 minutes or longer at an intervals of 24 hours. •The treatment period with this medicine is determined based on your symptoms. Precautions while taking this medicine •Keep all appointments/laboratory test schedules if periodic blood test is needed. Possible adverse reactions to this medicine The most commonly reported adverse reactions include fever and rash. If any of these symptoms occur, consult with your doctor or pharmacist. The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. •bronchospasm, angioedema, respiratory distress [shock, anaphylactoid symptoms] •dizziness, tinnitus, decreased hearing [8th cranial nerve disorder] •high fever, erosion in lips/genitalia, bloodshot eyes [toxic epidermal necrolysis, muco-cutaneo-ocular syndrome, erythroderma (exfoliative dermatitis)] •high fever, sore throat, gum bleeding [agranulocytosis, leucopenia, thrombocytopenia] •decreased urine output, edema, thirst [acute renal failure] The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. Meiji Seika Pharma Co., Ltd.Injection Published: 2/2015 The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment. --------------------------------------------------- 产地国家: 日本 原产地英文商品名: TEICOPLANIN for I.V. Infusion（テイコプラニン点滴静注用）200mg/vial  10vial/box 原产地英文药品名: Teicoplanin 中文参考商品译名: TEICOPLANIN（テイコプラニン点滴静注用）200毫克/瓶   10瓶/盒 中文参考药品译名: 替考拉宁 生产厂家中文参考译名: 明治制果有限公司制药 生产厂家英文名: Meiji Seika Pharma Co --------------------------------------------------- 产地国家: 日本 原产地英文商品名: TEICOPLANIN for I.V. Infusion（テイコプラニン点滴静注用）400mg/vial  10vial/box 原产地英文药品名: Teicoplanin 中文参考商品译名: TEICOPLANIN（テイコプラニン点滴静注用）400毫克/瓶   10瓶/盒 中文参考药品译名: 替考拉宁 生产厂家中文参考译名: 明治制果有限公司制药 生产厂家英文名: Meiji Seika Pharma Co 该药品相关信息网址1:http://www.info.pmda.go.jp/go/pack/6119401D1159_1_01/