2025年1月25日 星期六
繁體中文
设为首页
加入收藏
当前位置:新特药品资料下载首页 >> 新特药品PDF说明书 >> Empliciti(elotuzumab 中文药名:埃罗妥珠单抗)

Empliciti(elotuzumab 中文药名:埃罗妥珠单抗)

授权形式:  免费版  作者/开发商:   
文件大小:  13.36 Kb  解压密码:   
软件语言:  简体中文  更新时间:  2016-07-08 
版本号:  1.0  软件平台:  Win2000/WinXP/Win2003 
软件类别:  国产软件  演示地址:   
评分等级:  ★★★★★  注册地址:   
 发布人:  admin  下载次数:  10(今日:1,本周:1,本月:1) 
插件认证:  无插件  浏览次数:  239 
本地下载: 下载地址
软件介绍

Empliciti(elotuzumab 中文药名:埃罗妥珠单抗)为一种新免疫刺激治疗新药,获美国FDA批准治疗多发性骨髓瘤
批准日期:2015年11月30日  公司:Bristol-Myers Squibb
Empliciti(埃罗妥珠单抗 elotuzumab)注射,供静脉使用
【适应症和用法】
Empliciti(elotuzumab)联合Revlimid(lenalidomide,来那度胺)和地塞米松(dexamethasone)用于既往已接受一至三种治疗方案的复发性或难治性多发性骨髓瘤(MM)患者的治疗。
【剂型和规格】
注射:300毫克或400毫克的单一剂量小瓶用于重构冻干粉末。
【用法用量】
来那度胺和地塞米松10毫克/千克每周静脉给药前两个周期,每2周一次,直到疾病进展或不可接受的毒性。
Premediate地塞米松,苯海拉明,雷尼替丁和对乙酰氨基酚。
EMPLICITI Rx
Add Drug To My List Compare to related Drugs View/edit/Compare drugs in my list
Select the drug indication to add to your list
EMPLICITI
Leukemias, lymphomas, and other hematologic cancers  Only 4 drugs may be compared at once

Generic Name and Formulations:
Elotuzumab 300mg, 400mg; per vial; lyophilized pwd for IV infusion after reconstitution; preservative-free.
Company:
Bristol-Myers Squibb
 
Select therapeutic use: Leukemias, lymphomas, and other hematologic cancers
Indications for EMPLICITI:
In combination with lenalidomide and dexamethasone, for the treatment of patients with multiple myeloma who have received 1–3 prior therapies.

Adult:
Give by IV infusion at initial rate of 0.5mL/min; may increase stepwise if no reactions develop; max rate 2mL/min. After 4 cycles, infusion rate may be increased up to max 5mL/min. Administer with lenalidomide and dexamethasone (see full labeling for dosing schedule). 10mg/kg every week for the first 2 cycles then every 2 weeks thereafter; continue until disease progression or unacceptable toxicity. Premedicate with dexamethasone, H1 blocker, H2 blocker, and acetaminophen before each infusion. Dose modifications: see full labeling.

Children:
Not established.

Contraindications:
Consult lenalidomide and dexamethasone prescribing information for contraindications before starting therapy.

Warnings/Precautions:
Interrupt infusion if Grade ≥2 infusion reactions occur and manage appropriately. Monitor for development of infections and treat promptly. Monitor for second primary malignancies. Monitor liver function periodically; discontinue if Grade ≥3 elevation of liver enzymes occur; consider resuming after return to baseline values. Pregnancy: not studied. Nursing mothers: not recommended.

Interactions:
May interfere with correct response classification in SPEP and serum immunofixation assays.

Pharmacological Class:
SLAMF7-directed immunostimulatory antibody.

Adverse Reactions:
Fatigue, diarrhea, pyrexia, constipation, cough, peripheral neuropathy, nasopharyngitis, upper respiratory tract infection, decreased appetite, pneumonia.

Note:
For lenalidomide and dexamethasone specific dosing and safety information, refer to the respective full prescribing labels.

Generic Availability:
NO

How Supplied:
Single-dose vial—1

相关下载
丙肝药物Daklinza获FDA批准用...
发表评论  【顶部】【关闭】 
评分: 小星星 小星星小星星 小星星小星星小星星 小星星小星星小星星小星星 小星星小星星小星星小星星小星星

验证码: 验证码,看不清楚?请点击刷新验证码 *          
 
更多表情››
  • 请遵守《互联网电子公告服务管理规定》及中华人民共和国其他各项有关法律法规。
  • 严禁发表危害国家安全、损害国家利益、破坏民族团结、破坏国家宗教政策、破坏社会稳定、侮辱、诽谤、教唆、淫秽等内容的评论 。
  • 用户需对自己在使用本站服务过程中的行为承担法律责任(直接或间接导致的),本站管理员有权保留或删除评论内容。
 

最新下载

· Empliciti(elotuzumab 中...
· Cinqair(Reslizumab Int...
· CABOMETYX(Cabozantinib...
· REVLIMID(lenalidomide)...
· CABOMETYX(cabozantinib...
· Zepatier(Elbasvir/Graz...
· Tagrisso tabs(osimertinib)
· Triumeq(abacavir, dolu...
· 全球药品(参比制剂)20...
· 全球药品(参比制剂)20...

推荐下载

· 安替可胶囊
· 来那度胺(Lenalidomide/R...
· Noxafil(泊沙康唑)FDA批...
· Sutent(舒尼替尼)
· Torisel (temsirolimus)说明书
· Restasis(环孢毒素眼用乳...
· Sprycel(dasatinib、大沙替...

下载排行

· Cinqair(Reslizumab Int...
· Empliciti(elotuzumab 中...
· CABOMETYX(Cabozantinib...
· Zepatier(Elbasvir/Graz...
· CABOMETYX(cabozantinib...