【中文品名】齐留通 【药效类别】抗哮喘药,抗炎药 【通用药名】ZILEUTON 【别 名】A-64007, ABT-077, Leutrol, Zyflo 【化学名称】Urea, N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxy- 【CA登记号】[111406-87-2] 【分 子 式】CHNOPS· 【用 途】用于风湿性关节炎、过敏性鼻炎、哮喘病和溃疡性结肠炎。 Zyflo和Zyflo CR (齐留通)是一种白三烯合成抑制剂。白三烯合成抑制剂通过终止某些可引起气道内水肿、收缩和黏液产生的物质形成而起效。Zyflo和Zyflo CR也是用于治疗哮喘。 Zyflo Commonly used brand name(s): In the U.S. Available Dosage Forms: Therapeutic Class: Anti-Inflammatory Pharmacologic Class: Leukotriene Pathway Inhibitor Uses For Zyflo This medicine is available only with your doctor's prescription. Zileuton immediate-release tablets (Zyflo(R)) were withdrawn from the U. S. market by Critical Therapeutics on February 12, 2008. The extended-release formulation of zileuton (Zyflo CR(R)), also manufactured by Critical Therapeutics, Inc, is still available. Before Using Zyflo Allergies Pediatric Geriatric Pregnancy Breast Feeding Interactions with Medicines Dihydroergotamine Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Astemizole Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Propranolol Interactions with Food/Tobacco/Alcohol Other Medical Problems Proper Use of zileuton Zileuton is used to prevent asthma attacks. It is not used to relieve an attack that has already started. For relief of an asthma attack that has already started, you should use another inhaled medicine that works quickly. If you have any questions about this, check with your doctor. Swallow the extended-release tablet whole. Do not crush, break, or chew it. To work properly, zileuton must be taken every day at regularly spaced times, even if your asthma seems better. Dosing The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (extended-release tablets): Storage Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use. Precautions While Using Zyflo Check with your doctor if you are using more inhalations (puffs) than usual of your inhaled bronchodilator to relieve an acute asthma attack. You may be taking other medicines for asthma along with zileuton. Do not stop taking or reduce the dose of the other medicines, even if your asthma seems better, unless you are told to do so by your doctor. You should limit the amount of alcohol you drink while you are taking this medicine. This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed and have problems with sleep. If you or your caregiver notice any of these side effects, tell your doctor right away. Zyflo Side Effects Check with your doctor immediately if any of the following side effects occur: Rare Incidence not known Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Less common Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products. 哮喘治疗药物zileuton的缓释剂型 SkyePharmaPLC宣布与美国的私人公司Critical治疗公司(CTI)达成协议开发口服哮喘病和慢性阻塞性肺病(COPD)治疗药物zileuton的一个控释剂型。 SkyePharma公司将与CTI公司合作,进一步开发该剂型,用于治疗中度到重度哮喘和COPD。一旦获得FDA批准,CTI将通过自己专业销售团队在美国上市该药。CTI将偿付SkyePharma的开发费用,而后者将获得zileuton的部分销售收入,SkyePharma将负责在法国生产该药。 Zileuton是一个口服5-脂加氧酶抑制剂,可以阻断白三烯形成。长期使用zileuton可以减少其他药物使用,如β受体阻断剂、口服或吸入激素,这些药物都有副作用。 美国FDA批准的ZyfloFilmtab标签中称zileuton不能用于急性哮喘发作治疗,处于肝病活动期的患者不能使用该药。在使用该药期间推荐进行肝功能监测。如果使用了Zyflo,茶碱的使用量可以减少50%,需要进行监测;使用普萘洛尔(propranolol)或华法令(warfarin)的患者也要接受监测,适当时候调整剂量。报告的唯一的与安慰剂组有显著性差异的不良反应为胃部不适,治疗组为8.2%,安慰剂组为2.9%。 中文参考商品译名: 生产厂家中文参考译名: |
zileuton(齐留通)-12小时有效治疗哮喘病良药简介:
【中文品名】齐留通
【药效类别】抗哮喘药,抗炎药
【通用药名】ZILEUTON
【别 名】A-64007, ABT-077, Leutrol, Zyflo
【化学名称】Urea, N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxy-
【CA登记号 ... 关键字:zileuton(齐留通)哮喘病
责任编辑:admin
|
最新文章更多推荐文章更多热点文章更多 |