美国哮喘变态反应免疫学会年会上的报道,用omalizumab(Xolair)(重组抗人免疫球蛋白IgE单克隆抗体)可以改善标准治疗难以控制的中重度哮喘的症状。 XOLAIRXolair InformationXolair is a popular antibody that is known to effectively help decrease some of the most common allergic responses that occur in the patient’s organism. Therefore, this drug is highly indicated in the case of patients who are suffering from asthma (especially allergy-based asthma). Xolair IndicationsXolair is a well known medical product that is generally prescribed to patients who are suffering from severe or moderate asthma. However, this medicine could also serve some other medical purposes that have not been listed in this guide. Ask your personal health care provider for more information about this medicine and its benefits. Xolair WarningsPatients whoa re suffering from known allergic reaction to this medicine should not be allowed to start taking Xolair. Furthermore, before, you are allowed to start taking this medicine, you should alert your personal health care specialist if you are allergic to any foods, dyes, preservatives or any other types of substances (this is known to include other medicines). If you also use a steroid medication, do not stop using the steroid suddenly. Patients who are following a long term treatment with this medicine are known to be more prone to developing some types of cancer such as skin, breast, salivary gland, prostate, etc. Ask your personal physician to tell you more about the risks that a treatment with this drug implies. Before you take your very first dose of this medicine, you should alert your physician if you are suffering from any other medical disorders, as you might not be allowed to start using Xolair or you might have to take smaller doses of this medicine. Your treatment with it should be closely monitored by your physician. Xolair Intake GuidelinesA patient who starts a treatment with Xolair for the first time should ask his or her personal physician to tell him exactly how and when to take each dose of Xolair. Do not deviate from any of your personal doctor’s advices. If you fail to understand some of them, you should ask a pharmacist, a nurse or a physician for more detailed indications. Carefully read the set of instructions from the medicine’s label. Xolair is unable to stop an asthma attack that is already in progress, as its actions are not fast enough to reverse the attack’s symptoms. You should ask your personal physician to prescribe you a fast acting medical product for your asthma attacks. You might have to take Xolair along with some other medicines, in order to get better results from your treatment with this medicine. Do not stop using this drug without your personal physician’s approval, as this could trigger some severe symptoms. Xolair DosageYou should ask your personal health care provider to tell you the exact dose of Xolair that you should use it on a regular basis, in order to make sure that you will get the proper benefic effects from your treatment with it. Do not make any adjustments to the dose that you have been prescribed without your personal doctor’s consent. Xolair OverdoseIn case you suspect that you might be suffering from an overdose with Xolair you should seek medical care as soon as possible. Contact your physician and your local poison control centre as soon as possible. We have no information regarding the possible side effects that could be triggered by an overdose with this medicine, although this medical condition should not trigger any life threatening side effects or symptoms. Xolair Missed DoseIn order to get the proper benefits from your treatment with Xolair, you should use this drug on a regular basis. Avoid missing any of your prescribed doses of this drug. If you happen to miss one, alert your personal health care provider and ask him or her for further advice and recommendations. Do not use double doses of this medicine, as this increases your risk of developing overdose. Xolair Side EffectsSeveral patients who have received this medicine have suffered from an extremely dangerous life-threatening and very severe allergy to this drug’s main components. An allergic reaction to this medicine is known to occur a couple of hours after the patient has been administered this medicine. If you happen to develop any symptoms of an allergic reaction (for example skin rash or hives; light-headedness, difficulty breathing; fainting; swelling of your lips, tongue, face, or throat) you should alert your personal health care specialist as soon as possible, as you are in need of professional medical attention at once. A prolonged treatment with this medicine (Xolair) could also trigger some other severe side effects that are known to include unusual bleeding or bruising, abnormal weakness, etc. Xolair could also trigger a series of less severe but far more common side effects like:
Xolair Drug ReactionsAsk your personal physician to give you a list of the medicines that are known to harmfully interact with Xolair. While you are being treated with this medicine you should avoid starting to use any other topical non prescription or prescription medicines while you are following a treatment with Xolair. Buy XolairBuy Xolair through our Online Pharmacy Escrow Service or at any Canada Pharmacy where it is sold. In some countries XOLAIR may also be known as: Omalizumab 【新药介绍】:Omalizumab (Xolair®) ( 0.5 % ) 、喉头或舌头水肿、血小板减少症和荨麻疹7。另外,由于每剂150毫克的omalizumab含有108毫克的蔗糖,所以应事先告知患有糖尿病、葡萄糖-半乳糖吸收不良症、果糖不耐性或缺乏蔗糖¬异麦芽糖酶的病人3 当IgE和巨细胞及嗜碱细胞表面具高亲和力的FcεRI接受体结合,并和过敏原交叉连结时,会开始启动过敏反应,导致这些作用细胞去颗粒化而释出组织胺、白三烯素、细胞激素( cytokines )及其他媒介物质。这些媒介物质和过敏性气喘的病理生理学相关,包括呼吸道肿胀、平滑肌收缩及改变与发炎过程相关的细胞活性,并造成过敏性疾病的症状,例如支气管收缩、黏液产生、哮喘、呼吸困难、胸部紧绷、鼻塞、打喷嚏、搔痒、流鼻水及鼻痒、流眼泪。 |
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XOLAIR(中文:奥马佐单抗,Omalizumab)-有效治疗成年人难治性哮喘简介:
美国哮喘变态反应免疫学会年会上的报道,用omalizumab(Xolair)(重组抗人免疫球蛋白IgE单克隆抗体)可以改善标准治疗难以控制的中重度哮喘的症状。 这些资料取自546例中重度过敏哮喘患者的III期临床试 ... 责任编辑:admin
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