|
药品名称
英文药名: Atripla (Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate Tablets)
中文药名: 依法韦恩茨/恩曲他滨/替诺福韦富马酸片
此药生产商:Bristol-Myers-Squibb 和 Gilead Sciences, LLC.
药品介绍
艾滋病即获得性免疫缺陷综合征(AIDS),是由艾滋病病毒(HIV)引起的一种传染病,其特征是HIV特异性攻击辅助性T淋巴细胞,造成免疫系统功能进行性破坏,导致各种机会性感染和相关肿瘤的发生。艾滋病已成为威胁全人类的重大传染病,从1981年美国报道第1例艾滋病到至今的25年间,艾滋病病毒在全世界迅速蔓延。联合国艾滋病规划署(UNAIDS)2006年12月的最新流行报告显示,目前全球现存HIV/AIDS患者3950万例,仅2006年1年间,就有430万新感染病例,290万人死于艾滋病。
艾滋病药Atripla含3种药物：依法韦恩茨(efavirenz)、恩曲他滨(emtricitabine)和富马酸替诺福韦酯（tenofovir disoproxil fumarate），服用剂量为每日一片。
FDA批准首个治疗1型人类免疫缺陷病毒(HIV-1)感染的复方片剂Atripla(含固定剂量依法韦仑、恩曲他滨和替诺福韦3种广泛使用的抗逆转录病毒药),可单独应用或与其他抗逆转录病毒药合用治疗HIV-1感染成年患者。Atripla也是第一种每次1片、每日只需服用1次治疗HIV/AIDS的药物,它符合推荐的HIV感染治疗原则??开始治疗时至少使用3种高效抗逆转录病毒药。
Atripla简化了HIV-1感染的治疗方法,患者更易坚持治疗,而且有助于减少耐药性的产生,以达到长期控制HIV-1感染的目的。一项纳入244例HIV-1感染患者的为期48周的临床研究证明,联合应用依法韦仑、恩曲他滨和替诺福韦这3种药物安全、有效,80%的患者HIV显著减少,CD4细胞数显著增多。
Atripla的标签包括一个警告框,即该药可导致乳酸酸中毒。慢性乙型肝炎患者在停用Atripla(FDA没有批准这个适应证)后可加剧乙肝感染。其他可能导致的严重不良事件包括严重肝毒性、肾损伤和重症抑郁。最常见的不良反应有头痛、头晕、腹痛、恶心、呕吐和皮疹。
任何疑问，请遵医嘱！
规格：600mg 200mg 300mg 90片/30片
英文药名: Atripla (Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate Tablets)
中文药名: 依法韦恩茨~恩曲他滨~替诺福韦富马酸片
生产厂家: Bristol Meyers Squibb
Buy Atripla Online
Atripla
Atripla Information
Atripla (also known as Efavirenz, Emtricitabine and Tenofovir) is antiviral drug which stops the HIV to reproduce in the human organism. Atripla contains in its composition two anti HIV medicines: non-nucleoside reverse transcriptase inhibitor (also abbreviated as NNRTI) and nucleoside reverse transcriptase inhibitors which fight the infection away from the human body.
Atripla Indications
Atripla is a medicine which is recommended in the persons who are suffering from HIV. This medicine is not a cure for HIV or for AIDS; it is not effective in the prevention of the passing the virus to other people. This medicine may be used to treat other medical conditions than those listed above; for more information, talk to your personal health care provider or to a pharmacist.
Atripla Warnings
Patients are recommended to inform their doctor if they are suffering from liver diseases, kidney diseases, bone problems, hepatitis infection, epilepsy, seizure disorders and a history of mental illness. Patients who are suffering from one or more of these diseases will not be able to take this medicine or they will be needing dosage adjustments and regularly tested during the treatment.
Women who are pregnant or preparing to get pregnant should not take Atripla without their doctor’s approval because this medicine is harmful for the baby. It is a well known fact that HIV can be passed to the baby in the cases in which the mother is not treated correctly during pregnancy; this is why it is very important to tell your doctor if you are pregnant, because he will know how to control the infection in order not to be passed to the baby.
Women are recommended not to breast feed during the treatment with Atripla, because even if the baby is healthy he can become infected with HIV through the breast milk. Atripla may lead to lactic acidosis (this is the build up of the lactic acid in the human organism). This medical condition may lead to the following symptoms: muscle pain, muscle weakness, breathing problems, nausea, vomiting, arrhythmias, stomach pain and numbness. Patients who experience these symptoms, even in the mild form, should inform their doctor as soon as they can, because these symptoms usually get worse and can lead to death.
Atripla Intake Guidelines
Usually, the personal healthcare provider or the doctor will tell the patients exactly how to take Atripla, in order to obtain visible results. Patients should listen carefully to the doctor’s indications and if they have further questions about the treatment and the medicine they should talk again with their personal healthcare provider or with their pharmacist. It is very important to take this medicine exactly as it is prescribed by the doctor and to refill your prescription before you run out of this drug, in order not to interrupt the treatment. In order for the patient to see the improvements during the treatment with Atripla, they should go to regular blood and liver exams.
Patients should keep this medicine at the room’s temperature, avoiding heat, direct light and moisture. Patients are recommended to take this medicine with a full glass of water on an empty stomach. In order to avoid or to lessen the side effects of Atripla, patients should take this medicine before going to sleep.
Atripla Dosage
Patients should take Atripla as the doctor prescribed them and not in larger or smaller quantities or for longer/shorter periods of time. Their personal healthcare provider will ask them to undergo regular blood tests to see how the disease evolves under the treatment with Atripla. Their doctor can also change their dose in order to get the best results from this treatment. It is recommended not to change the dose of the medication nor its schedule without talking to you doctor first.
Atripla Overdose
The patients who believe that they have taken an overdose of Atripla should call their doctor as soon as possible and should also announce the local poison center. It is possible for the patients to remain in the hospital for further investigations and blood tests. The symptoms of an Atripla overdose remain unknown for the moment, but taking into consideration the side effects of this medicine the patients may experience: muscle pain, breathing problems, stomach pain, dizziness, shortness of breath, lightheadedness, irregular heartbeats, weakness, cold and blue hands and feet, enlarged liver, persistent nausea, abnormal dreams, kidney problems, loss of appetite and even uncontrollable muscle contractions.
Atripla Missed Dose
Patients should try as much as possible to respect the treatment’s schedule, but if they happen to miss a dose, they should take it as soon as they remember. When it is almost time for the next dose, patients are recommended to forget about their skipped dose and continue with their normal schedule. Patients must not take a double dose of Atripla, unless their doctor tells them to do so.
Atripla Side Effects
It is well known the fact that any medicine has its side effects. In the case of Atripla, patients might experience the following side effects during the treatment: nausea, dizziness, diarrhea, fatigue, headaches, vomiting, sinus infection, abnormal dreams, sore throat, colds, runny nose, and drowsiness. This is not a complete list of the side effects which can appear during the treatment, for further information we recommend you to discuss with your doctor.
Atripla Drug Reactions
Patients are recommended not to use Atripla if they are already under treatment with one or more of the following medicines: Astemizole, Cispriade, Lamivudine, Midazolam, Voriconazole, Methysergide, or other similar medicines. One should avoid combining his or her intake of this medicine (Atripla) with a therapy with Emtricitabine, Tenofovir or Efavirenz, antibiotics, antifungals, antihistamines, antipsychotics, heart medications, sedatives, antimigrain drugs, because this can lead to a life threatening interaction.
Buy Atripla
Buy Atripla through our Online Pharmacy Escrow Service or at any Canada Pharmacy where it is sold. |
