【药物名称】善胃得Zantac 【别名】呋硫消胺;呋喃硝胺;甲硝呋胍;拉弟克;善胃得;胃安太定;西斯塔;善得康 ,盐酸雷尼替丁 【外文名】Ranitidine 【性状】 常用其盐酸盐,为类白色或淡黄色结晶性粉末;有异臭,味微苦带涩;极易潮解,吸潮后颜色变深。在水中或甲醇中易溶,在乙醇中略溶,在丙酮中几乎不溶。熔点137-143℃。 【药理作用】 为一选择性H2受体拮抗剂,能有效的抑制组胺、五肽胃泌素及食物刺激后引起的胃酸分泌,降低胃酸和胃酶的活性,但对胃泌素及性激素的分泌无影响。 【适应症】主要用于治疗十二指肠溃疡、良性胃溃疡、术后溃疡、反流性食管炎及卓-艾综合征等。静注可用于上消化道出血。 【用法用量】口服,0.15g/次,2次/日,早晚饭时服;或0.3g睡前顿服;维持剂量为0.15g,睡前顿服。佐林格-埃利森综合征宜用大剂量,600mg~1200mg/日。肌注或缓慢静注,25mg~50mg/次,每4~8h 1次。静滴,100mg~300mg。 【注意事项】 【药物相互作用】 1.与普鲁卡因胺并用,可使普鲁卡因胺的清除率降低。 2.可减少肝脏血流量,因而与普萘洛尔、利多卡因等代谢受肝血流量影响大的药物合用时,可延缓这些药物的作用。 【规格】 片剂:每片150mg。胶囊剂:每胶囊150mg。 【类别】抗酸及抗溃疡药 【生产企业】 葛兰素史克 GlaxoSmithKline Zantac即善卫得,为阻织胺H2-受体拮抗剂。能抑制基础胃酸和刺激引起的胃酸分泌,可使胃酸减少,胃蛋白酶活性降低而且具有速效和长效的特点。 常用于治疗消化性溃疡、返流性食管炎、佐林格-埃利森综合征及上消化道出血等。 【原产地英文商品名】ZANTAC-PPI 20mg/cap 42caps/box Zantac ----------------------------------------------------------------------- What is Zantac? Zantac is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Zantac also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn. Zantac may also be used for other purposes not listed in this medication guide. ----------------------------------------------------------------------- Do not use Zantac if you are allergic to ranitidine. Ask a doctor or pharmacist if it is safe for you to take this medicine if you have kidney disease, liver disease, or porphyria. Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling. Zantac granules and effervescent tablets must be dissolved in water before you take them. Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it. Avoid drinking alcohol. It can increase the risk of damage to your stomach. It may take up to 8 weeks of using Zantac before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment. ----------------------------------------------------------------------- Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling. Ask a doctor or pharmacist if it is safe for you to take Zantac if you have: FDA pregnancy category B. Zantac is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Ranitidine passes into breast milk. Do not take Zantac without telling your doctor if you are breast-feeding a baby. Using Zantac may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia. The Zantac effervescent tablet may contain phenylalanine. Talk to your doctor before using this form of ranitidine if you have phenylketonuria (PKU). ----------------------------------------------------------------------- Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it. Do not crush, chew, or break the Zantac effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water. Allow the Zantac effervescent tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth. Zantac granules should be mixed with 6 to 8 ounces of water before drinking. Measure Zantac liquid with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. It may take up to 8 weeks before your ulcer heals. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 6 weeks of treatment. This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Zantac. Store Zantac at room temperature away from moisture, heat, and light. ----------------------------------------------------------------------- ----------------------------------------------------------------------- Overdose symptoms may include lack of coordination, feeling light-headed, or fainting. ----------------------------------------------------------------------- ----------------------------------------------------------------------- Less serious Zantac side effects may include: This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. ----------------------------------------------------------------------- There may be other drugs that can interact with Zantac. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. |
善胃得|Zantac(ranitidine tablets)简介:
【药物名称】善胃得Zantac 【英文名】Ranitidine
【别名】呋硫消胺;呋喃硝胺;甲硝呋胍;拉弟克;善胃得;胃安太定;西斯塔;善得康 ,盐酸雷尼替丁
【外文名】Ranitidine
【性状】
常用其盐 ... 责任编辑:admin |
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