通用名称BANZEL
使用rufinamide 200毫克，400毫克;得分标签。

法律分类：
接收

药理班BANZEL
抗癫痫（三唑）。

制造商BANZEL
卫材制药
适应症BANZEL
在癫痫发作的辅助治疗Lennox - Gastaut综合征（LGS的）。

成人剂量BANZEL
带着2相等剂量的食物。最初400每日800毫克;由400-800mg/day每2天增加至目标3200mg/day。避免突然停止（减少25％每2天剂量）。

儿童剂量为BANZEL
带着2相等剂量的食物。 <4yrs：不推荐。 ≥4yrs：最初每天10mg/kg的加大，隔日由每天10mg/kg的目标或3200mg/day 45mg/kg（以较低者为准）。避免突然停止（减少25％每2天剂量）。

禁忌的BANZEL
家族性短QT综合征。

警告/注意事项的BANZEL
严重肝功能不全：不推荐。轻度至中度肝功能不全。透析（可调节剂量）。抑郁或有自杀意念（监视器）。妊娠（Cat.C）。哺乳母亲：不推荐。

互作BANZEL
药物警告说，QT间期缩短。中枢神经系统抑郁症与酒精，镇静剂等中枢神经系统。拮抗卡马西平，拉莫三嗪。会增强苯巴比妥，苯妥英，三唑仑。 Potentiated由丙戊酸钠（减少剂量）。拮抗卡马西平，苯巴比妥，primidone，苯妥英。 CYP3A4的可能影响，细胞色素P450 2E1（显示器）基板。拮抗（使用非激素形式太）荷尔蒙避孕药具。可能受到诱导或羧酸酯酶抑制剂。

不良反应为BANZEL
嗜睡，疲劳，运动失调，眩晕，步态障碍，共济失调，头痛，胃肠不适，视力障碍，白细胞减少，发热/皮疹（显示器多器官超敏反应）。

如何BANZEL提供？
制表符为200mg - 30
为400mg - 120

BANZEL

Generic Name for BANZEL

Rufinamide 200mg, 400mg; scored tabs.

Legal Classification:

Rx

Pharmacological Class for BANZEL

Antiepileptic (triazole).

Manufacturer of BANZEL

Eisai Pharmaceuticals

Indications for BANZEL

Adjunctive treatment of seizures in Lennox-Gastaut syndrome (LGS).

Adult dose for BANZEL

Take with food in 2 equally divided doses. Initially 400–800mg per day; increase by 400–800mg/day every 2 days to target of 3200mg/day. Avoid abrupt cessation (reduce dose by 25% every 2 days).

Children's dosing for BANZEL

Take with food in 2 equally divided doses. <4yrs: not recommended. ≥4yrs: initially 10mg/kg per day; increase every other day by 10mg/kg to target 45mg/kg per day or 3200mg/day (whichever is less). Avoid abrupt cessation (reduce dose by 25% every 2 days).

Contraindications for BANZEL

Familial short QT syndrome.

Warnings/Precautions for BANZEL

Severe hepatic impairment: not recommended. Mild to moderate hepatic impairment. Dialysis (may adjust dose). Depression or suicidal ideation (monitor). Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions for BANZEL

Caution with drugs that shorten QT interval. CNS depression with alcohol, other CNS depressants. Antagonizes carbamazepine, lamotrigine. May potentiate phenobarbital, phenytoin, triazolam. Potentiated by valproate (reduce doses). Antagonized by carbamazepine, phenobarbital, primidone, phenytoin. May affect substrates of CYP3A4, CYP2E1 (monitor). Antagonizes hormonal contraceptives (use non-hormonal forms too). May be affected by inducers or inhibitors of carboxylesterases.

Adverse Reactions for BANZEL

Somnolence, fatigue, incoordination, dizziness, gait disturbances, ataxia, headache, GI upset, visual disturbances, leukopenia, fever/rash (monitor for multi-organ hypersensitivity reaction).

How is BANZEL supplied?

Tabs 200mg—30
400mg—120