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当前位置:药品说明书与价格首页 >> 心血管系统 >> 高血压 >> 药品推荐 >> TEVETEN HCT(甲磺酸依普沙坦/氢氯噻嗪复方片剂)

TEVETEN HCT(甲磺酸依普沙坦/氢氯噻嗪复方片剂)

2011-05-28 10:57:59  作者:新特药房  来源:中国新特药网天津分站  浏览次数:189  文字大小:【】【】【
简介: 高血压治疗药Teveten HCT新药 Teveten HCT于2001年11月获得了FDA 批准,适应证是高血压。 Teveten HCT是甲磷酸Eprosartan 和氢氯噻嗪的复方制剂。 甲磷酸Eprosartan是血管紧张素 Ⅱ抑制剂。血管紧张素 ...

Generic Name for TEVETEN HCT
Eprosartan (as mesylate), hydrochlorothiazide; 600mg/12.5mg, 600mg/25mg; tabs.

Legal Classification:
Rx

Pharmacological Class for TEVETEN HCT
Angiotensin II receptor blocker + diuretic.

Manufacturer of TEVETEN HCT
Abbott Laboratories
 

Indications for TEVETEN HCT
Hypertension.

Adult dose for TEVETEN HCT
Not for initial therapy. May be substituted for titrated components. One Teveten HCT 600mg/12.5mg tab once daily; after 2–3 weeks may increase to one Teveten HCT 600mg/25mg tab once daily. May add eprosartan 300mg once daily in the PM if additional BP control is needed at trough.

Children's dosing for TEVETEN HCT
Not recommended.

Contraindications for TEVETEN HCT
Anuria. Sulfonamide allergy. Pregnancy (Cat.D in 2nd and 3rd trimesters).

Warnings/Precautions for TEVETEN HCT
Correct salt/volume depletion before starting, or monitor closely. Renal or hepatic dysfunction. Renal artery stenosis. Severe CHF. Asthma. Diabetes. Postsympathectomy. SLE. Gout. Monitor electrolytes. Elderly. Pregnancy (Cat.C in 1st trimester). Nursing mothers: not recommended.

Interactions for TEVETEN HCT
Digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. Hyperkalemia with K+ supplements, K+ sparing diuretics, or K+ containing salt substitutes. ACTH, corticosteroids, amphotericin B increase hypokalemia risk. Orthostatic hypotension potentiated by alcohol, CNS depressants. Antagonized by NSAIDs. Potentiates other antihypertensives. May potentiate nondepolarizing muscle relaxants. May interfere with parathyroid tests. May antagonize norepinephrine.

Adverse Reactions for TEVETEN HCT
Dizziness, headache, back pain, fatigue, orthostatic hypotension, electrolyte disturbances, rash, adverse lipid values, rhabdomyolysis (rare).

How is TEVETEN HCT supplied?
Tabs—100

Related Disease:
Hypertension


Pharmaceuticals开发,商品名:Teveten HCT,于2001年11月获得FDA批准,适应征是高血压。
                           
依普罗沙坦为选择性的、非二苯基、非四唑类血管紧张素Ⅱ受体拮抗剂。通过拮抗血管紧张素Ⅱ发挥作用,阻滞血管紧张素醛固酮系统激活,来抑制血压升高。由史克必成公司开发,其商品名为Teveten。Smithkline Beechan公司研制,荷兰solvay公司获许可,于1997年7月首先在德国上市,商品名为Teveten;1997年12月美国FDA批准ABBOTT (雅培)在美上市;2 0 0 0年在英国和澳大利亚上市。甲磺酸依普罗沙坦/氢氯噻嗪2001年12月美国FDA批准ABBOTT (雅培)在美上市。国内进口,依普沙坦片,H20070400 ,solvay公司进口。

【原产地英文商品名】TEVETEN HCT (600/12.5)mg/tab 100tabs/bottle
【原产地英文药品名】EPROSARTAN MESYLATE/HYDROCHLOROTHIAZIDE
【中文参考商品译名】
注:以下产品不同规格和不同价格,购买时请以电话咨询为准!
·TEVETEN HCT (600/12.5)毫克/片 100片/瓶
·TEVETEN HCT (600/25)毫克/片 100片/瓶
【中文参考药品译名】甲磺酸依普沙坦/氢氯噻嗪
【生产厂家中文参考译名】雅培
【生产厂家英文名】ABBOTT

 

Teveten HCT
Generic Name: Eprosartan

What is Teveten HCT?
Teveten HCT is a combination medication consisting of eprosartan (a blood pressure lowering agent) and hydrochlorothiazide (a diuretic or "water pill"). It is used to treat high blood pressure, alone or in combination with other blood pressure medications.

What is the most important information I should know about Teveten HCT?
Do not use Teveten HCT during the second or third trimester of pregnancy. This drug can cause injury and even death to the developing baby. Tell your doctor immediately if you think you might be pregnant.

You must take Teveten HCT regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Teveten HCT. You must continue taking it even if you are feeling well. Teveten HCT does not cure blood pressure, but keeps it under control.

Teveten HCT can cause an excessive drop in blood pressure, especially when you first begin taking it. Tell your doctor if you feel lightheaded or faint. If you do faint, stop taking Teveten HCT until you see your doctor. Fainting is more likely if you are dehydrated, due to inadequate intake of fluids, excessive sweating, diarrhea, or vomiting.

Excessive fluid loss can also lead to a chemical imbalance in the body. Warning signs include dry mouth, thirst, diminished urination, weakness, lack of energy, drowsiness, restlessness, confusion, seizures, muscle pain, muscle fatigue, nausea, vomiting, and rapid heartbeat. Alert your doctor if you develop any of these symptoms.

Who should not take Teveten HCT?
Do not take Teveten HCT if you are pregnant, if you have ever had an allergic reaction to it, or if you cannot urinate or are sensitive to other sulfonamide drugs.

What should I tell my doctor before I take the first dose of Teveten HCT?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Teveten HCT. Also, talk to your doctor about your complete medical history, especially if you have a history of allergy, wheezing or breathing difficulties, kidney or liver disease, lupus (a disease that affects the immune system), joint inflammation, high blood sugar, or parathyroid disease.

What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: Teveten HCT comes in 2 strengths: 600/12.5 and 600/25 (600 milligrams [mg] of eprosartan and either 12.5 mg or 25 mg of hydrochlorothiazide). The usual starting dose is one 600/12.5 tablet per day. If your blood pressure remains too high, the doctor may increase the dose to one 600/25 tablet per day.

How should I take Teveten HCT?
Teveten HCT can be taken with or without food. Try to establish a regular routine by taking it at the same time each day: in the morning with breakfast, for example. This reduces the chance that you'll forget a dose.

Lightheadedness is a common side effect when taking Teveten HCT during the first few days. Inadequate fluid intake may be the reason. If you lose consciousness while taking Teveten HCT, discontinue taking it and consult your doctor.

What should I avoid while taking Teveten HCT?
Teveten HCT may cause dizziness or drowsiness. Use caution when driving, operating machinery, or performing other hazardous activities.

Avoid prolonged exposure to sunlight or artificial UV light (tanning beds). Teveten HCT may increase the sensitivity of the skin to sunlight and you may be sunburned as a result. Use a sunscreen and wear protective clothing when you are outside.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Teveten HCT.

Avoid salt substitutes and do not take potassium supplements without first talking to your doctor.

What are possible food and drug interactions associated with Teveten HCT?
If Teveten HCT is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Teveten with any of the following: barbiturates, such as phenobarbital or secobarbital; cholestyramine; colestipol; insulin; lithium; narcotic painkillers, such as meperidine or oxycodone; nonsteroidal anti-inflammatory medications, such as ibuprofen or naproxen; oral diabetes medications, such as glipizide or glucotrol; other blood pressure medications, such as atenolol or nifedipine; potassium-sparing diuretics (water pill), such as amiloride, spironolactone, or triamterene; potassium supplements; and steroid medications, such as prednisone.

What are the possible side effects of Teveten HCT?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: back pain, dizziness, fatigue, headache, inflamed sinus, upper respiratory tract infection, weakness

Can I receive Teveten HCT if I am pregnant or breastfeeding?
Teveten HCT can cause injury or even death to an unborn baby, especially when used in the second or third trimester of pregnancy. Stop taking Teveten HCT as soon as you know you are pregnant, and be sure to tell your doctor if you are pregnant or plan to become pregnant. Teveten HCT may appear in breast milk. Do not breastfeed while taking Teveten HCT.

What should I do if I miss a dose of Teveten HCT?
If you miss a dose of Teveten HCT, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

How should I store Teveten HCT?
Store at room temperature.

责任编辑:admin


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