繁体中文
设为首页
加入收藏
当前位置:药品说明书与价格首页 >> 激素类 >> 新药推荐 >> SOMATROPIN(RECOMBINANT,重组人生长激素)

SOMATROPIN(RECOMBINANT,重组人生长激素)

2012-06-28 21:44:50  作者:新特药房  来源:中国新特药网天津分站  浏览次数:346  文字大小:【】【】【
简介: EuroPharm Somatropin Somatotropin, also commonly referred to as human growth hormone (HGH), is a hormone that is produced in the human body and excreted into the blood by the somatotrope ...

EuroPharm Somatropin

Somatotropin, also commonly referred to as human growth hormone (HGH), is a hormone that is produced in the human body and excreted into the blood by the somatotrope cells of the anterior pituitary gland. It is a single-chain protein that is composed of 191 amino acids with a molecular weight of approximately 22,000 Daltons. GH secretion has many direct and indirect effects on the human body. First, GH stimulates the liver's production of insulin-like growth factor (IGH-1). Because GH stimulates the liver's production of IGF-1, the effects of both GH and IGF-1 are listed below. Synthetic version of Human Growth Hormone is called Somatropin (191 amino acid sequence growth hormone). It is identical to human body's own GH. However that is not the case for Somatrem (192 amino acid sequence growth hormone). But we will talk about that later Direct and Indirect Effects of Somatotropin on the Human Body: Stimulates division and multiplication of the chondrocytes of cartilage Increases both calcium retention and the mineralization of bones Stimulates cell growth in every organ of a human body Increases metabolism Repairs damaged cells Induces protein synthesis Decreases protein degradation Stimulates the immune system Promotes lipolysis Increases glucose transport In the human body, somatotropin is at its highest levels in children and during puberty, stimulating the growth of the body during those ages.
 
After puberty, the level of growth hormone secretion declines and continues to do so as a person ages. Growth hormone deficiency (GHD) is a disease in which a person's pancreas fails to produce an adequate amount of normal endogenous growth hormone. In children, this results in short stature and growth failure. In adults, GHD causes deficiencies of strength, energy, and bone mass. GHD can be treated in both children and adults with somatropin, also known as synthetic human growth hormone (HGH). However, to treat conditions of height, a child must be treated before the growth plates (epiphyses) at the ends of long bones have fully matured and closed. Healthy adults most commonly use Human Growth Hormone for Anti Aging, Body Building and Fat Loss purposes.

Information on HHT INJ

Somatropin 191AA is a high quality recombinant Human Growth Hormone (HGH) powder in lyophilized (freeze-dried) format, 191 amino acids for optimal compatibility with the human endocrine system and a product purity of 99%.
Direct and Indirect Effects of Somatropin 191lAA on the Human Body:
Greater cardiac output
Increased muscle mass
Superior immune function
Enhanced human sexual performance
Lowered blood pressure
Improved cholesterol profile
Reduced body fat
Higher energy levels
Increased exercise performance
Supplement stronger bones
Younger, tighter, thicker skin
Hair re growth
Wrinkle removal
Re-generation of major organs that shrink with age

For anti-aging, general health & healing and fat mobilization, a dose of 2-3 IU's per day will be sufficient for the majority. A dose of 1.5 to 2.0 IU's is considered to be a full replacement dose for those middle-aged and beyond. For gaining lean muscle and substantially improving body composition a dose of 4-8 IUs per day will be necessary. Most people will respond very well at a dose of 4-5 IU's per day.
Storage temperature thresholds - Store 35 - 46 degrees Fahrenheit (2 - 8 degrees C) which means you should store
the product in your refrigerator and not in your freezer. Somatropin 191AA can be exposed to room temp for up to 3 months.
Mix with Sterile or Bacteriostatic Water.
------------------------------------------------------
部分中文 HHT INJ 处方信息(仅供参考)

[通用药名]基因重组人生长激素 
[药品成分]本品是由191个氨基酸残基或N端有一甲硫氨酸的192个氨基酸残基组成的蛋白。 
[作用与用途]本品具有与人体生长激素同等的作用,即能促进骨骼、内脏和全身生长,促进蛋白质合成,影响脂肪和矿物质代谢
,在人体生长发育中起着关键性作用。皮下注射约80%被吸收,5小时后达高峰血浓度,t1/2约4小时。主要用于内源性脑垂体生长激素分泌不足而引起的生长障碍、躯体矮小的侏儒症、短小病患儿。此外,尚可用于治疗烧伤、骨折、创伤、出血性溃疡、组织坏死、肌肉萎缩症、骨质疏松等疾病。
[用法与用量]本品给药剂量个体差异很大,采用肌内注射或皮下注射,一般用量为每周0.5—0.7单位/kg或每周12单位/m2,
分6—7次给药。
[注意事项]偶可引进皮肤过敏、注射部位发红和皮下脂肪萎缩、氨基转移酶升高、呕吐及腹痛等。
1.肿瘤患者、糖尿病患者、颅内进行性损伤者禁用。
2. 对脑肿瘤的垂体抹儒病者、心脏或肾脏病者、孕妇和哺乳妇女等慎用。
3.使用前,需对脑垂体功能作详细检查,准确诊断后才能应用。
4.应临用时配制,用注射用水溶解,轻轻摇动,切勿振荡,以免变性。

责任编辑:admin


相关文章
RIXUBIS(Coagulation Factor IX [Recombinant])注射剂
Norditropin Simplexx Injection(诺德欣注射液(诺和诺德))
生长激素注射剂|Saizen(Somatropin Injection)
美国FDA批准Natpara注射液为治疗甲状旁腺功能减退新药
HumatroPen(somatropin [rDNA origin] for injection)
HUMATROPE(SOMATROPIN RECOMBINANT for injection)
ELOCTATE(抗血友病因子[(重组),Fc融合蛋白]注射剂)
Puregon(重组促卵泡素β注射液)
HYLENEX(HYALURONIDASE RECOMBINANT HUMAN)
RIXUBIS(Coagulation Factor IX [Recombinant])冻干粉
Norditropin NordiFlex(基因重组人生长激素注射笔)
 

最新文章

更多

· Norditropin Simplexx I...
· 生长激素注射剂|Saizen(...
· REGPARA TABLETS(Cinac...
· Signifor(Pasireotide s...
· Sandostatin(Octreotide...
· SOL-MELCORT for inject...
· hCRH TANABE Injection(...
· Gonal-f RFF(follitropi...
· Sandostatin LAR kit(醋...
· Somatuline for s.c. In...

推荐文章

更多

· Norditropin Simplexx I...
· 生长激素注射剂|Saizen(...
· REGPARA TABLETS(Cinac...
· Signifor(Pasireotide s...
· Sandostatin(Octreotide...
· SOL-MELCORT for inject...
· hCRH TANABE Injection(...
· Gonal-f RFF(follitropi...
· Sandostatin LAR kit(醋...
· Somatuline for s.c. In...

热点文章

更多

· 生长激素注射剂|Saizen(...
· Norditropin Simplexx I...