普瑞巴林的部分中文处方资料（仅供参考）
产品名称: 普瑞巴林
药理药效：普瑞巴林是一种新型γ-氨基丁酸(GABA)受体激动剂,能阻断电压依赖性钙通道,减少神经递质的释放,临床主要用于治疗外周神经痛以及辅助性治疗局限性部分癫痫发作。
别名: C1-1008
化学名称: (3S)-3-氨甲基-5-甲基己酸
美国化学文摘登录号: [ 148553-50-8 ]
分子式: C8H17NO2
分子量: 159.23
物化性质： 白色结晶性粉末
LYRICA
Generic Name and Formulations:
Pregabalin 30mg,25mg, 50mg, 75mg, 100mg, 150mg, 200mg, 225mg, 300mg; caps.
Company:
Pfizer Inc.
Indications for LYRICA:
Fibromyalgia.
Adult Dose for LYRICA:
≥18yrs: initially 75mg twice daily, may increase to 150mg twice daily within 1 week as tolerated; max 450mg/day. Renal impairment (CrCl <60mL/min): reduce dose (see literature); hemodialysis: give supplemental dose after session.
Children's Dose for LYRICA:
<18yrs: not recommended.
See Also:
LYRICA ORAL SOLUTION
Pharmacological Class:
alpha2-delta ligand.
Warnings/Precautions:
Avoid abrupt cessation (taper over ≥1 week). Discontinue if angioedema, hypersensitivity reactions, myopathy or markedly elevated creatine kinase levels occur. CHF. Ocular conditions. Diabetes (monitor skin integrity). Suicidal tendencies (monitor). Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Interactions:
Potentiates CNS depression with alcohol, other CNS depressants. Additive edema, weight gain with thiazolidinediones.
Adverse Reactions:
Dizziness, somnolence, other CNS effects, dry mouth, edema, ocular/visual effects (eg, blurring), weight gain, thinking abnormal (primarily difficulty with concentration/attention), infection, asthenia, paresthesias, elevated creatine kinase, decreased platelets, arrhythmias (PR prolongation); male-mediated teratogenicity; may be tumorigenic.
How Supplied:
Caps—90; Soln—16oz
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产地国家: 意大利
原产地英文商品名:
LYRICA 30MG/CAP 14CAPS/BTL
原产地英文药品名:
PREGABALIN
中文参考商品译名:
LYRICA 30毫克/胶囊 14胶囊/瓶
中文参考药品译名:
普瑞巴林
生产厂家中文参考译名:
辉瑞公司
生产厂家英文名:
Pfizer