脂类调节剂 -Lovaza Caps(Omega-3-acid ethyl esters)
“Lovaza”是一种特别的鱼油脂类调节剂,葛兰素史克药厂研发,目前被美国食品药品管理局(FDA)唯一批准为饮食辅助药物以降低成年患者的甘油三酸脂(³ 500 mg/dL)水平。Lovaza 每胶囊1克,含有 465 mg EPA,375 mg DHA,折算成900 mg omega-3脂肪酸乙酯 。
Generic Name and Formulations:
Omega-3-acid ethyl esters 1g; soft-gelatin caps; contains α-tocopherol 4mg/cap.
Company:
GlaxoSmithKline Pharmaceuticals
Indications for LOVAZA:
Adjunct to diet to reduce very high (≥500mg/dL) triglyceride levels in adults.
Adult Dose for LOVAZA:
Swallow whole. ≥18yrs: 4g daily; may take as 4g once daily or as 2g twice daily.
Children's Dose for LOVAZA:
<18yrs: not established.
Pharmacological Class:
Lipid-regulating agent.
Warnings/Precautions:
Hepatic impairment: monitor AST/ALT periodically. Obtain baseline triglycerides (TG); monitor TG, LDL-C periodically. Exclude and/or treat secondary causes of hypertriglyceridema (eg, hypothyroidism, diabetes, medications). Paroxysmal or persistent atrial fibrillation. Fish allergy. Pregnancy (Cat.C). Nursing mothers.
Interactions:
May potentiate anticoagulants; monitor.
Adverse Reactions:
Eructation, dyspepsia, rash, taste perversion; increased ALT, AST, LDL-C.
Note:
This product was formerly named Omacor.
Generic Availability:
NO
How Supplied:
Caps—60, 120