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阿拉普利片|CETAPRIL(ALACEPRIL Tablets)

2014-04-05 01:09:06  作者:新特药房  来源:互联网  浏览次数:292  文字大小:【】【】【
简介:部份中文阿拉普利处方资料(仅供参考)【中文品名】阿拉普利【药效类别】抗高血压药【通用药名】ALACEPRIL【别  名】Cetapril,DU-1219, DU-1227【化学名称】 L-Phenylalanine, 1-[(2S)-3-(acetylthio)-2-met ...

部份中文阿拉普利处方资料(仅供参考)
【中文品名】阿拉普利
【药效类别】抗高血压药
【通用药名】ALACEPRIL
【别  名】Cetapril,DU-1219, DU-1227
【化学名称】 L-Phenylalanine, 1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-L-propyl-
【CA登记号】[74258-86-9], [74259-08-8]
【结 构 式】


【分 子 式】C20H26N2O5S
【分 子 量】406.50
【收录药典】JP14
【开发单位】大日本制药株式会社 (日本)
【首次上市】1988年,日本
【性  状】白色结晶粉末。mp155~157℃。[α]D26 = -81.6°(C=1, 乙醇)
【用  途】
血管紧张素转化酶抑制剂。用于治疗高血压和充血性心力衰竭。其作用强度为卡托普利的4倍。本品因不含巯基,故皮疹、味觉改变、血尿等副作用较低,适宜病人长期治疗用药。
【药理及应用】为合巯基的ACEI,在体内转化为卡托普利而起作用。降压作用产生较慢,持久。口服吸收良好。用于高血压,心肌缺血,心力衰竭.
【适 应 症】高血压症,肾性高血压症
【用法用量】口服,每次25~50mg,每日3次。予增加或减少,取决于患者的年龄和症状。此外,甚至在严重的情况下100毫克,每天最大剂量。
【包装规格】

12.5毫克:100片(10片×10),1000片(10片×100)
25毫克:100片(10片×10),500粒(瓶),500片(10片×50),1000片(10片×100)1400片(14片×100),3000片(10粒×300)
50毫克:140片(14片×10),700片(14片×50)
【制造厂商】
大日本住友制药有限公司
完整资料附件:
http://www.info.pmda.go.jp/go/pack/2144003F1029_1_15/

セタプリル錠12.5mg/セタプリル錠25mg/セタプリル錠50mg

CETAPRIL Tablets(Alacepril)
CETAPRIL Tablets 12.5mg(セタプリル錠12.5mg)
Brand name : CETAPRIL Tablets 12.5mg
 Active ingredient: Alacepril
 Dosage form: white tablet, diameter: 6mm, thickness: 2.3mm
 Print on wrapping: セタプリル錠, 12.5mg, P321
CETAPRIL Tablets 25mg(セタプリル錠25mg)
Brand name : CETAPRIL Tablets 25mg
 Active ingredient: Alacepril
 Dosage form: white tablet, diameter: 7mm, thickness: 2.1mm
 Print on wrapping: セタプリル錠, 25mg, P322
CETAPRIL Tablets 50mg(セタプリル錠50mg) 
Brand name : CETAPRIL Tablets 50mg
 Active ingredient: Alacepril
 Dosage form: white tablet, major axis: 11.6mm, minor axis: 5.8mm, thickness: 3.2mm
 Print on wrapping: セタプリル錠, 50mg, P323
Effects of this medicine
This medicine blocks angiotensin-converting enzyme in order to suppress vasopressor system and to enhance depressor system, and consequently to lower blood pressure.
It is usually used to treat essential/renal hypertension.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you ever had angioedema.
If you are receiving apheresis and dialysis.
If you are a patient with diabetes mellitus.
•If you are pregnant, breastfeeding or possibly pregnant.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is ((to be written by a healthcare professional))
•In general, for adults, take 1 to 3 tablets (25 to 75mg of the active ingredient) in 1 to 2 divided doses a day. The dose may be adjusted according to your age and symptoms. The maximum dose is 4 tablets (100mg) a day. Strictly follow the instructions.
•If you miss a dose, take the missed dose. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
•If you accidentally took more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•You may feel dizziness/lightheadedness due to decreased blood pressure. Pay close attention performing dangerous operation such as driving a car, operating machinery or working at height.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include cough, rash, dizziness, nausea, lightheadedness, general malaise, anemia, itch and taste abnormality. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•respiratory distress, swollen eyelids/lips/tongue, hives [angioedema]
•sore throat, headache, high fever with chills or shiver [agranulocytosis]
•blister of various sizes appearing on the skin/mucous membrane, breakable blister, severe itchiness throughout the body [pemphigus-like symptoms]
•numbness in the limbs/lips, muscle weakness, paralyzed limbs [hyperkalemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder. Do not store them.
Sumitomo Dainippon Pharma Co.,Ltd.Internal
Revised: 2/2016
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


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