英文药名：MAGTECT(Aluminum Hydroxide Gel/Magnesium Hydroxide)

中文药名：氢氧化铝凝胶/氢氧化镁配合分包液

生产厂家：Nichi-iko
治疗类别名称
-Suspension型胃溃疡和胃炎的治疗剂
欧文商標名
MAGTECT
氢氧化铝凝胶
一般名：
水酸化アルミニウムゲル （Aluminum Hydroxide Gel）
分子式：
Al(OH)3・nH2O
性状：
与白色粘性，当它被静置悬浮液，它是分离少量的水在上层中，如果混合摆动，并返回到悬浮液中。
物理和化学知识：其他氢氧化铝凝胶

氢氧化镁
一般名：
水酸化マグネシウム（Magnesium Hydroxide）
分子式：
Mg(OH)2　分子量：
58.32
性状：
白色粉末，无臭味。
和在水中或不溶于乙醇。
此产品溶于稀盐酸。
物理和化学知识：等氢氧化镁

操作注意事项
为了避免误用，而不是保存转移到其他的容器中。
存储在它不是放在儿童不能接触的地方。
这种药物，因为它可以通过光线，避免光线会变色。
稳定性试验
每加速试验此产物（40℃，75％，6个月的相对湿度）进行，Magutekuto复合口服液香囊据推测它的结果通常是对在市场分配3年稳定。
药效药理
通过药效学试验的生物等效性试验
幽门结扎溃疡的抑制作用
使用SD大鼠，试验制剂和标准配方（溶液）的结果进行比较，并在18小时后幽门结扎后空腹口服单剂量检测幽门结扎溃疡的抑制作用，这两种药物的对照组和安慰剂组我发现一个显著的抑制作用。此外，没有显著差异，观察在两种药物之间的影响，这两种药物的生物等效性，确认.
水浸束缚应激性溃疡的抑制作用
使用SD大鼠，测试准备和禁食的标准制定（解决方案），单剂量口服至23℃，一项研究比较了5个小时，这两种药物的对照组浸水应激性溃疡的抑制作用和安慰剂组的结果它表明在一个显著抑制作用。此外，没有显著差异，观察在两种药物之间的影响，这两种药物的生物等效性进行了确认.
吲哚美辛溃疡抑制作用
使用SD大鼠，对结果进行比较，以吲哚美辛的溃疡抑制作用在空腹的测试制剂和标准制剂（液体）的单剂量口服，两种药物显示对对照组一个显著抑制作用和安慰剂组这是。此外，没有显著差异，观察在两种药物之间的影响，这两种药物的生物等效性，确认.
乙醇溃疡的抑制效应
使用SD大鼠，结果在空腹的测试制剂和标准配方（液体）比较乙醇溃疡抑制作用的单剂量口服，两种药剂显示对对照组和安慰剂组显著抑制作用这是。此外，没有显著差异，观察在两种药物之间的影响，这两种药物的生物等效性进行了确认。
适应症
改善抗酸作用和症状以下疾病
胃及十二指肠溃疡，胃炎，上消化道功能紊乱
用法用量
每天20〜45毫升，成人为分次口服给药。此外，将根据自己的年龄，症状进行调整。
包装规格：
10ml×126包

生产厂商
Nichi-iko Pharmaceutical Co
MAGTECT COMBINATION ORAL SOL pack（Aluminum Hydroxide Gel/Magnesium Hydroxide）
MAGTECT COMBINATION ORAL SOL pack（マグテクト配合内服液分包）
Brand name: MAGTECT COMBINATION ORAL SOL pack
　Active ingredient: Aluminum hydroxide gel
 Magnesium hydroxide
　Dosage form: white viscous suspension
　Print on wrapping: 禁注射,内服用,マグテクト配合内服液分包,10mL,日医工
Effects of this medicine
This medicine has antacid effect and adheres to gastric mucosa to protect the mucosa from the acid of the stomach.
It is usually used in the improvement of symptoms caused by gastric/duodenal ulcer, gastritis and upper gastrointestinal tract dysfunction.
Before using this medicine, be sure to tell your doctor and pharmacist
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you are on dialysis.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
In general, for adults, take 20 to 45ml a day, in several divided doses. It should be adjusted according to disease, age and symptoms of the patient. This preparation contains 10ml in a package. Strictly follow the instructions.
Shake the package well before opening because this medicine is a suspension.
DO NOT use this medicine besides oral administration. Take this medicine immediately after open the package and discard the liquid left in the package.
Read the instruction, <患者さんへ (For the patients) >, about the way to open the package (This instruction is written only in Japanese) .
If you miss a dose, take a dose as soon as possible when you remembered that you missed a dose. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
Be aware of taking this medicine with a large amount of milk and calcium preparation because it may cause adverse effects such as hypercalcemia.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include anorexia, nausea, gastric discomfort, constipation, diarrhea and anemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep out of the reach of children. Store away from direct sunlight, heat, moisture and freezing.
To avoid misuse, do not transfer this medicine to other container for storage.
Discard the remainder. Do not store them.
Nichi-iko Pharmaceutical Co.,Ltd Internal
Revised: 12/2012
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00058347