英文药名：PREDONEMA Enema（Prednisolone phosphate ester sodium）
中文药名：泼尼松龙磷酸酯钠灌肠剂
生产厂家：杏林制药
治疗类别名称
溃疡性结肠炎，局限性肠炎治疗剂
欧文商標名
PREDONEMA Enema 20mg
一般名：
プレドニゾロンリン酸エステルナトリウム（JAN）
別名：
リン酸プレドニゾロンナトリウム
化学名：
11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(disodium phosphate)
構造式：
分子式：C21H27Na2O8P
分子量：484.39
性状
本品为白色粉末为淡黄色。它易溶于水，微溶于甲醇，和乙醇（99.5）几乎不溶。本品是一种吸湿性
操作注意事项
结果，外观和内容等的最终包装产品长期保存试验使用（25℃，相对湿度60％，3年）都是标准的，Puredonema灌肠20毫克三年在正常的市场分布稳定的范围内3，其已经被确定为是）。
药效药理
对浆膜在乙酸注射溃疡性结肠炎模型大鼠，泼尼松龙磷酸酯为0.3mg/kg时，降低了显著溃疡表面的作用下观察为0.1mg/kg的给药灌肠。
适应症
溃疡性结肠炎，局限性肠炎
用法用量
成年人，以灌肠施用（20毫克强的松龙磷酸酯）22mg作为单剂量泼尼松龙磷酸钠酯（直肠输注）。此外，增加或减少取决于患者的年龄和症状。
包装规格：
灌肠剂：20mg
1本（60毫升）*7本
生产商：
杏林制药
* Other Description
<How to use the Puredonema enema 20mg>
1. (If necessary) water bath with warm
Depending on the room temperature, you may chemical solution to stimulate the cold stomach. It remains of aluminum bags that case, please warmed to about body temperature dipped in hot water.
2. Removal from the aluminum bag
Please remove the container from the aluminum bag immediately before use.
Because this drug is unstable in light, after opening aluminum bag should be used immediately.
3. (If required) attached stopper
Because the length of the nozzle enters there are individual differences, there is a risk that damage to the rectal mucosa by over insertion. Please use such as when it is first to use it by mounting a stopper.
Using the stopper
Plug a single disk-shaped stopper a guide about 4-6cm from the tip of the nozzle as shown in the figure below.
4. (If necessary) the coating of the lubricant
If it is difficult nozzle is inserted, lubricants (petroleum jelly, olive oil or water) Please use painted.
5. How to hold the container at the time of opening
The surface on which characters are entered in the "Puredonema" as shown in the figure below is in front, so please have lightly the body portion toward the nozzle to the top.
When squeezing strongly the container at the time of opening, because there is a possibility that the drug solution pops out, be sure to have lightly.
6. How to detach the chip
It has a circular flange, and bend the "constriction" part back and forth once slowly, out of the normal chip, looks like a chemical solution comes out.
In addition, the chip looks like a chemical solution comes out deviated chip even if not completely disconnected.
When bent to the left and right (horizontal) direction and diagonal direction, it may cause a leak.
7. Insertion and injection of chemical liquid nozzle
(1) it is the nozzle portion is inserted slowly and carefully from the anus.
Do not insert the never impossible. It may damage the rectal mucosa and forcibly inserted.
(2) After slowly injecting a chemical solution in a state in which the left hip was down, while clutching a container, and gently pull.
8. (If necessary) repositioning
Make Positions conversion as necessary.
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