英文药名：Flucam Capsules（ampiroxicam） 中文药名：安吡昔康胶囊 日文药名：フルカムカプセル 生产厂家：辉瑞日本公司 治疗类别名称 镇痛，抗炎剂 商標名 Flucam Capsules 一般名 アンピロキシカム（ampiroxicam） 化学名 (±)-4-[1-(ethoxycarbonyloxy)ethoxy]-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide 分子式 C20H21N3O7S 分子量 447.47 融点 約156℃（分解） 構造式 性状 安吡昔康是白色的结晶粉末的黄色。该产品易溶于冰醋酸或二甲基甲酰胺，略溶于乙腈，微溶于甲醇或乙醚，乙醇和极微溶于，它是几乎不溶于水。 药效药理 1. 抗炎症作用 安吡昔康抑制作用角叉菜胶足水肿，几乎相同的吡罗昔康，比阿西美辛稍强。即使对于跌打损伤水肿（大鼠）和紫外线红斑（豚鼠），安吡昔康的功效是等同于吡罗昔康，较阿西美辛强。肉芽肿形成由棉花球法（大鼠），甚至对于亚急性，慢性炎症诸如佐剂性关节炎（大鼠），表现出相同的抗炎作用和炎痛喜康。 2. 镇痛作用 醋酸扭体（鼠）安吡昔康的抑制效果比得上炎痛喜康和阿西美辛。对炎症性疼痛的大鼠足垫（兰德尔-Selitto方法）的抑制效果，是等同于吡罗昔康和阿西美辛。此外，对佐剂关节痛（大鼠）的镇痛效果也相媲美的炎痛喜康和阿西美辛。 3. 作用机序 安吡昔康旨在口服给药后转换，炎痛喜康在从肠道被吸收的过程。活性成分吡罗昔康的作用抑制花生四烯酸代谢的环氧合酶被认为是由于抑制其参与炎症，疼痛的前列腺素的生物合成。 适应病症 下面镇痛的疾病和症状，抗炎 风湿性关节炎 骨关节炎 下背部疼痛 肩周炎 颈肩臂综合症 用法用量 成人每天口服为27mg。另外，它要取决于患者的年龄，症状来用药。 包装规格 胶囊 13.5mg  100,500胶囊（PTP） 27mg    100 500 700胶囊（PTP） 生产厂商 辉瑞日本公司 Flucam Capsules 13.5mg（フルカムカプセル13.5mg） Brand name : Flucam Capsules 13.5mg 　Active ingredient: Ampiroxicam 　Dosage form: pale yellow capsule, diameter 5.1 mm, length 14.2 mm 　Print on wrapping: フルカム13.5mg, FLUCAM13.5mg, FC13.5  Flucam Capsules 27mg（フルカムカプセル27mg）  Brand name : Flucam Capsules 27mg 　Active ingredient: Ampiroxicam 　Dosage form: pale yellow-green capsule, diameter 6.2 mm, length 17.8 mm 　Print on wrapping: フルカム27mg, FLUCAM27mg, FC27 Effects of this medicine This medicine inhibits production of prostaglandin (substance that induces inflammation or enhances the pain), thus relieves joints or muscle pain by suppress the inflammation and swelling. Usually, used for anti-inflammation/relieve pain such as rheumatoid arthritis, osteoarthritis, low back pain, periarthritis scapulohumeralis, cervico-omo-brachial syndrome. Before using this medicine, be sure to tell your doctor and pharmacist •If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. •If you have: peptic ulcer, hematological disorder, hepatic impairment, renal impairment, aspirin asthma or history of it, cardiac dysfunction, hypertension, bleeding tendency, bronchial asthma. •If you are pregnant or breastfeeding. •If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.) Dosing schedule (How to take this medicine) •Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>> •In general, for adults, take 1 capsule (27mg of the active ingredient) once a day after meal. The dose should be adjusted according to your disease, age and symptoms. The maximum daily dose is up to 1 capsule (27 mg). Strictly follow the instructions. •If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time. •If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist. •Do not stop taking this medicine unless your doctor instructs you to do so. Precautions while taking this medicine • Possible adverse reactions to this medicine The most commonly reported adverse reactions include pain or discomfort in the stomach/abdomen, swelling, rash, photosensitivity, itch, eczema, rubor and hives. If any of these symptoms occur, consult with your doctor or pharmacist. The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. •abdominal pain, vomiting, hematemesis/melena [peptic ulcer, gastrointestinal bleed] •breathing difficulty, generalized hot flash, hives [shock, anaphylactoid symptom] •high fever, redness of skin, stomatitis [Stevens-Johnson syndrome, toxic epidermal necrosis] •decreased urine output, swelling, headache [acute renal failure] •symptoms of anemia, bleeding tendency, fever [aplastic anemia, myelosupression] The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. Storage conditions and other information •Keep out of the reach of children. Store away from direct sunlight, heat and moisture. •Discard the remainder. Do not store them. Pfizer Pharmaceuticals Inc.Internal Revised: 11/2009 The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.