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当前位置:药品说明书与价格首页 >> 眼科 >> 青光眼 >> 药品推荐 >> LATANOPROST Ophthalmic Solution 0.005%(拉坦前列素滴眼液)

LATANOPROST Ophthalmic Solution 0.005%(拉坦前列素滴眼液)

2016-03-07 03:53:43  作者:新特药房  来源:互联网  浏览次数:0  文字大小:【】【】【
简介: 英文药名:LATANOPROST Ophthalmic Solution 0.005%(Latanoprost) 中文药名:拉坦前列素滴眼液0.005% 日文药名:ラタノプロスト点眼液0.005%「科研」 生产厂家:科研制药治疗类别名称前列腺 ...

英文药名:LATANOPROST Ophthalmic Solution 0.005%(Latanoprost)
 
中文药名:拉坦前列素滴眼液0.005%

日文药名:ラタノプロスト点眼液0.005%「科研」

生产厂家:科研制药
治疗类别名称
前列腺素F2α衍生物,青光眼和高眼压症治疗剂
药理作用
拉坦前列腺素是一种新型苯基替代的丙基酯前列腺素F2α,为选择性F2α受体激动药。它是一种无活性但能迅速渗透到角膜里的物质,在角膜和血浆中可水解为具有活性的游离酸。它能增加房水通过眼角素层的流出量,用药量小,但促进房水流出量大,药液能渗透到眼球脉络膜上层,具有良好降眼压效果。本品还可使青光眼患者通常会堵塞的眼球小梁筛网结构通畅。
药动学
本品在角膜中水解为游离酸,这种游离酸从角膜扩散出来并进入房水中,约2h可达到血药峰值。3~4h后眼压开始下降,8~12h达到最大下降幅度,维持24h眼压不升高。该药在房水流出时被排出,半衰期约为2h。通过结膜或黏膜产生全身吸收,被吸收的药物在血液循环系统,经肝代谢后主要随尿排泄。
适应证
适用于开角型青光眼,以及用其他药物难以治疗或耐受的眼压过高患者的局部治疗。
禁忌证
1.孕妇、哺乳期妇女禁用。
2.严重哮喘或眼睛发炎充血期间等患者禁用。
注意事项
1.儿童不推荐使用。
2.本品不适用于治疗闭角型或先天性青光眼,色素沉着性青光眼以及假晶状体的开角型青光眼。
3.本品与其他抗青光眼药物联合使用具有协同作用,所用其他滴眼药,应至少间隔5min滴用。
4.佩戴角膜接触镜者应先摘掉镜片,滴入药物15min后才能戴上镜片。
不良反应
本品通常耐受良好,偶见视力模糊、烧灼痛、刺痛、结膜充血、短暂点状角膜糜烂和异物感。某些患者还会出现虹膜的棕色色素沉着(6个月后有7%,12个月后达16%)。色素增加在有绿棕色、蓝灰棕色或黄棕色虹膜的人种较为多见,在纯蓝色、蓝灰色或绿色的人种中则较罕见。这是由于黑色素形成的刺激引起的,停药后即可停止进展,但明显不能恢复。
用法用量
滴眼:每天1次,每次1滴,最好于晚间滴于患眼
包装规格
2.5mL×10


生产商
科研制药有限公司
LATANOPROST Ophthalmic Solution 0.005%(Latanoprost)
LATANOPROST Ophthalmic Solution 0.005% "KAKEN"(ラタノプロスト点眼液0.005%「科研」) 
Brand name : LATANOPROST Ophthalmic Solution 0.005% "KAKEN"
 Active ingredient: Latanoprost
 Dosage form: clear and colorless sterile eye solution (2.5mL)
 Print on wrapping: ラタノプロスト点眼液0.005%「科研」, 2.5mL
Effects of this medicine
This medicine lowers eye pressure by increasing fluid drainage from the aqueous outflow pathway of the eye.
It is usually used to treat glaucoma and ocular hypertension.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: aphakic eye or pseudophakic eye, intraocular inflammation (e.g. iritis, uveitis), possible herpesvirus infection, bronchial asthma or history of bronchial asthma.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, apply 1 drop at a time, once a day. Strictly follow the instructions.
•Wash hands down and apply carefully not to touch the dropper tip against the eye.
•Wipe off any excess liquid with a clean wet gauze or tissue.
•If you are using other eye drops at the same time, wait more than 5 minutes.
•If you are wearing contact lenses, take off the lenses and then administer. Wait more than 15 minutes to wear your contact lenses again. (It might lead contact lenses to discoloration).
•If you miss a dose, apply one drop once if it is within the day. You should never apply twice a day nor two drops at a time when you noticed the missed dose the next day. (By the frequent dosage, intraocular pressure decreasing action may attenuate.)
•If you accidentally use more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop using this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
•Applying the eye-drops may cause iris pigmentation, followed by gradual increase of the symptom. The symptom may stop after withdrawal of the eye-drops, but there may be difference in color tone compared to the other eye without eye-drop treatment. If you become aware of it, check with your doctor.
•This medicine may cause transient blurred vision. Avoid driving a car or operating machinery until these symptoms recover.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include conjunctival hyperaemia, ocular irritancy symptom, itching, eye pain, blepharitis (eye lid infection), eyelid pigmentation, blurred vision, abnormal eyelash, visual acuity decrease, lacrimation, headache, throat discomfort and nausea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•pupil color change [iris pigmentation]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from light, heat and moisture.
•Discard the remainder. Do not store them.
Kaken Pharmacetical Co.,LtdExternal
Published: 5/2010
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
http://meds.qlifepro.com/detail/621984501/latanoprost

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