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当前位置:药品说明书与价格首页 >> 耳鼻喉 >> 鼻炎 >> Zyrtec Dry syrup 1.25%(盐酸西替利嗪干糖浆剂)

Zyrtec Dry syrup 1.25%(盐酸西替利嗪干糖浆剂)

2016-08-03 06:29:42  作者:新特药房  来源:互联网  浏览次数:6  文字大小:【】【】【
简介: 英文药名:Zyrtec Dry syrup(Cetirizine Hydrochloride) 中文药名:盐酸西替利嗪干糖浆剂 生产厂家:第一三共制药 ジルテックドライシロップ1.25% 治疗类别名称选择H1受体拮抗剂,过敏性疾病治 ...

英文药名:Zyrtec Dry syrup(Cetirizine Hydrochloride)

中文药名:盐酸西替利嗪干糖浆剂

生产厂家:第一三共制药

ジルテックドライシロップ1.25%

治疗类别名称
选择H1受体拮抗剂,过敏性疾病治疗药物
商標名
Zyrtec
一般名
セチリジン塩酸塩(Cetirizine Hydrochloride)
化学名
2-(2-{4-[(RS)-(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid dihydrochloride
構造式

分子式
C21H25ClN2O3・2HCl
分子量
461.81
融点
204~210℃(分解)
性状
它是一种白色结晶粉末。非常易溶于水,乙醇(99.5)微溶。易溶于0.1mol / L的盐酸测试解决方案。水溶液(1→10)示出了没有旋光性。
分配系数
24.3(pH值为7,水 - 辛醇系统)
药效药理
1. 组胺H1受体拮抗剂
通过选择性地结合组胺H1受体,抑制组胺的作用。组胺H2,多巴胺,乙酰胆碱,对血清素的每个受体的亲和力低(大鼠,豚鼠),在大鼠中枢神经系统组胺H1受体的影响较小。切除器官的组胺反应(人类支气管平滑肌)呈剂量依赖性地抑制。此外,能够抑制组胺诱导的皮肤反应和组胺诱导的鼻部症状,效果立即和可持续的(人)。
2. 嗜酸性粒细胞上的作用
在体外和抗嗜酸性粒细胞体内,抑制过氧化物的产生迁移抑制指示嗜酸性粒细胞活化(人)。
3. 介质释放的抑制作用
从人的肺切片抑制白三烯和前列腺素D2释放。
适应病症
成人:
过敏性鼻炎,荨麻疹,湿疹,皮炎,痒疹,瘙痒
小儿:过敏性鼻炎,瘙痒与荨麻疹,皮肤疾病(湿疹,皮炎,皮肤瘙痒症)
用法用量
成人:
一天一次,每次0.8克(10毫克),使用时睡前口服给药。
此外,年龄,将根据症状进行调整,最高剂量一天1.6克(20毫克)
小儿:不到2岁或以上的7岁一次0.2克每天(2.5mg),口服给药,在早餐前使用。
在孩子超过15岁或7岁,和口服给药一天0.4克(5毫克)在早餐前使用。
包装规格
干糖浆剂 1.25%
12.5mg/克
0.4g x 100包;0.8gx100包;散装100g


制造商
UCB日本有限公司[联盟]第一三共有限公司
完整资料附件:http://www.info.pmda.go.jp/go/pack/4490020R1027_2_05/
Zyrtec Dry syrup 1.25%(ジルテックドライシロップ1.25%) 
Brand name : Zyrtec Dry syrup 1.25%
 Active ingredient: Cetirizine hydrochloride
 Dosage form: dry syrup, white grayish white
 Print on wrapping: 5mg/包(0.4g) ジルテックドライシロップ1.25% 0.4g(1包中)
10mg/包(0.8g) ジルテックドライシロップ1.25% 0.8g(1包中)
Effects of this medicine
This medicine exhibits histamine H1 receptor antagonism and improves symptoms caused by allergy.
For adults, it is usually used to treat allergic rhinitis, hives, eczema/dermatitis, prurigo, and dermal pruritus. For children, it is usually used to treat allergic rhinitis, hives, itch of skin disorder (eczema/dermatitis, dermal pruritus).
Before using this medicine, be sure to tell your doctor and pharmacist
•If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you have renal or liver disorder.
If you have convulsive disorder such as epilepsy, or history of this disease.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•General dosage regimen: For adults, take 0.8g (10mg as active ingredient) once a day, before bedtime by dissolving the medicine in water just before use. The dose may be adjusted according to your age and symptoms. The dose can be increased up to 1.6g (20mg) per day according to need. For children aged between 2 to 6 years: take 0.2g (2.5mg), aged between 7 to under 15 years: take 0.4g (5mg), twice a day, after breakfast and before bedtime by dissolving the medicine in water just before use. Strictly follow the instructions of your doctor/pharmacist.
•Take the missed last dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. DO NOT take a double dose to make up for the missed dose.
•If you took too much of this medicine (more than ordered), check with your doctor/pharmacist.
•Do not stop taking this medicine without the instructions of your doctor.
Precautions while taking this medicine
•This medicine may make you sleepy. Do not drive a car or operate dangerous machinery just after taking it.
•Drinking alcohol while taking this medicine may intensify sleepiness or lassitude.
Possible adverse reactions to this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist:
In adults, sleepiness, lassitude, dry mouth, nausea, floating dizziness, headache, rash, etc. In chidren, sleepiness, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•breathing difficulty, decrease in blood pressure, hives [shock, anaphylactoid symptoms]
•convulsion [convulsion]
•generalized fatigability, appetite loss, yellowness in the skin and the white of the eye [liver dysfunction, jaundice]
•nose/gums bleeding, subcutaneous bleeding [thrombocytopenia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from heat, moisture and direct sunlight.
•Discard the remainder. Do not store them.
DAIICHI SANKYO COMPANY, LIMITEDInternal
Revised: 5/2016
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

责任编辑:admin


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