【剂　　型】 片剂（胶囊剂）
【化学名称】 2-[（二苯基甲基）亚硫酰基]乙酰胺
【分 子 式】 C15H15NO2S
【分 子 量】 273.36
【适应症状】 抑郁症患者。特发性嗜睡或发作性睡眠症。
【用法用量】 口服。每日睡前1.5小时服50～100mg，每4～5天增加50毫克，直至最适剂量（每日200～400毫克）
【性　　状】 本品为白色或类白色的结晶性粉末；无臭、几乎无味。本中种在甲醇中略溶，在乙醇或乙酸乙酯中微溶，在水中几乎不溶。
【注意事项】 严重肝损害的患者剂量减半，肾功能不全和老年患者服用剂量要酌减，左室肥大、有缺血性心 电图改变、胸痛、心律失常或有临床表现的二尖瓣脱垂的患者及近期发生心肌梗 塞、不稳定型心绞痛或有精神病史者禁用或慎用。
【包装规格】 胶囊剂（片剂）：每粒（片）含本品20mg，100mg， 200mg，瓶装100粒（片）

美国发明不眠药“不夜神”

转载自 新华网2002-6-26

6月26日电据海外媒体报道，美国科学家研制成一种名为MODAFINIL的新药，健康人服用一片后，能劲头十足地连续工作40小时而不犯困，接下来睡上8小时，再吃一片，还可连续工作40小时。

报道说，这种新药可能使一些人的生活方式及习惯发生巨大变化。美国联邦食品和药物管理局已批准该药上市，但只能用于间发性嗜睡病患者。该药能使病人摆脱睡意的纠缠，正常工作，却不会出现异常兴奋等副作用，也不会使病人服药成瘾。发明这种新药的美国CEPHALON药厂已以“不夜神”(PROVIGIL)为品牌在市场上推出这一新药。

纽约大学睡眠紊乱中心主任沃尔斯莱本预言：“‘不夜神’将取代咖啡因”，成为全世界使用最普遍的药物。“不夜神”目前还没有在市场上全面推开，但仅去年一年，它的销售额已达1.5亿美元。生产商很快将向美国联邦食品和药物管理局提出申请，要求把销售范围扩大到其它睡眠不好的人群，如：呼吸暂停病人和帕金森氏病患者。

【原产地英文商品名:Provigil -100MG x100tablets
【原产地英文药品名】MODAFINIL
【原产地英文化合物名称】2-(benzhydrylsulfinyl)acetamide C15-H15-N-O2-S
【中文参考商品译名】
注：以下产品不同规格和不同价格，购买时请以电话咨询为准！
·Provigil -100毫克x100片/瓶
·Provigil -200毫克x100片/瓶
【中文参考药品译名】MODAFINIL, 不夜神
【生产厂家中文参考译名】美国CEPHALON药厂
【生产厂家英文名】CEPHALON

Information on Provigil

Learn more about usage, cautions, and possible side effects.

Tablets
Chemical Name: MODAFINIL

Common uses
This medicine is an anti-narcoleptic agent used to improve wakefulness in patients with narcolepsy (sudden uncontrollable attacks of daytime sleepiness), obstructive sleep apnea/hypopnea syndrome, or in patients with shift work sleep disorder. It may also be used to treat other conditions as determined by your doctor.

Before using
Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking birth control pills. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

Directions
Follow the directions for using this medicine provided by your doctor. Take this medicine in the morning unless otherwise directed by your doctor. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If you do not remember until late afternoon or evening, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Cautions
DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed. Exceeding the recommended dose or taking this medicine for longer than prescribed may be habit-forming. AVOID ALCOHOL while you are using this medicine. USING THIS MEDICINE ALONE, WITH OTHER MEDICINES, OR WITH ALCOHOL may lessen your ability to drive or to perform other potentially dangerous tasks. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of this medicine unless your doctor tells you to do so. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED when using this medicine in children because they may be more sensitive to the effects of this medicine. FOR WOMEN TAKING BIRTH CONTROL PILLS, this medicine may decrease the effectiveness of your birth control pills. To prevent pregnancy, use an additional form of birth control while you are taking this medicine and for 1 month after stopping this medicine. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects
SIDE EFFECTS that may occur while taking this medicine include nausea, nervousness, headache, dizziness, or trouble sleeping. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Drug interactions
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions

If you take too much
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose include fast heartbeat, trouble sleeping, agitation, and restlessness.

Additional information
If your symptoms do not improve or if they become worse, check with your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

Selected data included with permission and copyrighted by Medi-Span, 2008. This copyrighted material has been downloaded from a Licensed data provider and is not for distribution in professional healthcare settings.