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吡喹酮片|Biltricide(Praziquantel Tablets)

2011-06-27 15:56:27  作者:新特药房  来源:中国新特药网天津分站  浏览次数:392  文字大小:【】【】【
简介: 通用名称为BILTRICIDE 吡喹酮600毫克;取得标签。 法律分类: 接收 药理班级BILTRICIDE Trematodicide。 制造商BILTRICIDE 默克制药公司 适应症BILTRICIDE 对于因感染治疗:血吸虫所有物种,和感染 ...

通用名称为BILTRICIDE
吡喹酮600毫克;取得标签。

法律分类:
接收

药理班级BILTRICIDE
Trematodicide。

制造商BILTRICIDE
默克制药公司
适应症BILTRICIDE
对于因感染治疗:血吸虫所有物种,和感染由于肝脏吸虫,华支睾吸虫/ Opisthorchis viverrini。

成人和儿童:
燕子与水用餐时的整体。 <4yrs:不推荐。 ≥4yrs:血吸虫病:20mg/kg,每日3次为一天的治疗间隔,≥4小时和6小时≤。华支睾吸虫,opisthorchiasis:25毫克,每日3次为一天的治疗间隔,≥4小时和6小时≤。

禁忌的BILTRICIDE
眼囊虫病。伴随强烈的CYP450诱导剂(如利福平)。

警告/注意事项为BILTRICIDE
中度至重度肝功能损害。癫痫的历史。脑囊虫病:送入医院对病人的治疗时间。监测心脏异常患者。妊娠(Cat.B)。哺乳母亲:不建议在随后的72hrs。

相互作用的BILTRICIDE
见禁忌。停止利福平前,吡喹酮4周;可能重新启动后完成吡喹酮治疗一天。 Potentiated由CYP450抑制剂(如西咪替丁,酮康唑,伊曲康唑,红霉素),西柚汁。拮抗CYP450诱导剂(如苯妥英,苯巴比妥,卡马西平,地塞米松),氯喹。

为BILTRICIDE不良反应
全身乏力,头痛,头晕,腹部不适,恶心,发热;罕见:荨麻疹。

如何BILTRICIDE提供?
标签- 6

BILTRICIDE

Generic Name for BILTRICIDE

Praziquantel 600mg; scored tabs.

Legal Classification:

Rx

Pharmacological Class for BILTRICIDE

Trematodicide.

Manufacturer of BILTRICIDE

Merck & Co., Inc.

Indications for BILTRICIDE

For the treatment of infections due to: all species of schistosoma, and infections due to the liver flukes, Clonorchis sinensis/Opisthorchis viverrini.

Adults and Children:

Swallow whole with water during meals. <4yrs: not recommended. ≥4yrs: Schistosomiasis: 20mg/kg 3 times daily as a one day treatment, at intervals ≥4hrs and ≤6hrs. Clonorchiasis, opisthorchiasis: 25mg/kg 3 times daily as a one day treatment, at intervals ≥4hrs and ≤6hrs.

Contraindications for BILTRICIDE

Ocular cysticercosis. Concomitant strong CYP450 inducers (eg, rifampin).

Warnings/Precautions for BILTRICIDE

Moderate to severe hepatic impairment. History of epilepsy. Cerebral cysticercosis: hospitalize patient for duration of treatment. Monitor patients with cardiac irregularities. Pregnancy (Cat.B). Nursing mothers: not recommended and during subsequent 72hrs.

Interactions for BILTRICIDE

See Contraindications. Discontinue rifampin 4 weeks before giving praziquantel; may be restarted one day after completing praziquantel treatment. Potentiated by CYP450 inhibitors (eg, cimetidine, ketoconazole, itraconazole, erythromycin), grapefruit juice. Antagonized by CYP450 inducers (eg, phenytoin, phenobarbital, carbamazepine, dexamethasone), chloroquine.

Adverse Reactions for BILTRICIDE

Malaise, headache, dizziness, abdominal discomfort, nausea, fever; rare: urticaria.

How is BILTRICIDE supplied?

Tabs—6

责任编辑:admin


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