部份色甘酸钠中文处方资料（仅供参考）
治疗类别名称
哮喘的治疗剂
中文通用名称: 色甘酸钠
英文通用名称: Sodium Cromoglicate
其 它 名 称: 咽泰,咳乐钠,色甘酸二钠,Inostral,Intal,Cromoglycate Sodium,Cromolyn,Cromolyn Sodium,色甘酸钠滴眼液,色甘酸钠气雾剂,色甘酸钠滴鼻液,Cromolyn Sodium Inhalation Aerosol Soln,Cromoglycate Disodium,Nalcrom,宁敏,衍行,Sodium Cromoglicate Aerosol,Sodium Cromoglicate Eye Drops,Sodium Cromoglicate for Inhalation,吸入用色甘酸钠,吸入用色甘酸钠胶囊,Sodium Cromoglicate Nasal Drops
产品分类:
西药呼吸系统用药平喘药过敏介质阻释药
适应症
1.可用于预防各型哮喘发作。
2.可用于过敏性鼻炎、季节性花粉症、春季角膜炎、结膜炎、过敏性湿疹及某些皮肤瘙痒症。
3.可用于溃疡性结肠炎和直肠炎。
用法用量
成人
•常规剂量
•吸入给药
1.支气管哮喘：
(1)干粉吸入：一次20mg，一日4次；症状减轻后，一日40-60mg；维持量，一日20mg。
(2)气雾吸入：一次3.5-7mg，一日3-4次，一日最大剂量32mg。
2.过敏性鼻炎：每侧一次10mg，一日4-6次。
•经眼给药季节性花粉症和春季过敏性角膜结膜炎：2%滴眼液，每侧一次2滴，一日4次，重症可适当增加到一日6次。在好发季节提前2-3周使用。
•外用过敏性湿疹及皮肤瘙痒症：5%-10%软膏涂患处。
•直肠给药溃疡性结肠炎、直肠炎：灌肠，一次200mg。
•肾功能不全时剂量
酌情减量。
•肝功能不全时剂量
酌情减量。
儿童
•常规剂量
•吸入给药
1.支气管哮喘：
(1)干粉吸入：5岁以上儿童用成人量，不能吸粉剂的幼儿避免使用。
(2)气雾吸入：
①6岁以上儿童：一日吸2次，剂量同成人。
②6岁以下儿童：很难做到使患儿协调吸药，故较少选用本药。
2.过敏性鼻炎：干粉吸入：6岁以上儿童，每侧一次10mg，一日2-3次。
•经眼给药结膜炎：4岁及4岁以上儿童，4%溶液，一次1-2滴，一日4-6次。
任何疑问,请遵医嘱!
给药说明
1.由于本药系预防性地阻断肥大细胞脱颗粒，而非直接舒张支气管，因此对于季节性外源性过敏原引起的支气管哮喘病例应在支气管哮喘好发时期前2-3周使用本药。运动性哮喘可在运动前15分钟给药。
2.极少数人在开始用药时出现哮喘加重，此时可先吸入少许扩张支气管的气雾剂，如异丙肾上腺素、沙丁胺醇。
3.原来用肾上腺皮质激素或其它平喘药治疗者，用本药后应继续用原药至少1周或至症状改善后，才能逐渐减量或停用原用药物。
4.获明显疗效后，可减少给药次数。如需停药，亦应逐步减量后再停，不能突然停药，以防哮喘复发。
5.本药对伴有肺气肿或慢性支气管炎的病人，疗效有限。对急性哮喘和哮喘持续状态无效。故如遇急性发作，应立即以常规方法治疗，并停用本药。
6.哮喘持续发作及严重呼吸困难者，色甘酸钠吸入不属首选治疗，应先用解痉药物或皮质激素以控制症状。
不良反应
1.偶见排尿困难、尿急、尿痛、头晕、严重或持续性头痛、喘鸣加重、关节痛或肿胀、肌痛或肌无力、恶心或呕吐、皮疹或皮肤瘙痒、口唇与眼睑肿胀、胸部紧束感、呼吸或吞咽困难等。
2.少数患者喷雾吸入干粉可出现鹗、咽喉干痒、呛咳、胸部紧迫感、鼻腔充血、支气管痉挛，甚至诱发哮喘。
3.对少数用滴鼻液、滴眼液的病人，初用时有局部刺激感。
[国外不良反应参考]
1.吸入可能导致短暂的支气管痉挛、喘鸣、咳嗽、鼻充血以及喉刺激症状。恶心、头痛、眩晕、味苦、关节疼痛和肿胀也有报道。在治疗几周或几个月后有时会出现其它一些反应，如哮喘加重、荨麻疹、肺嗜酸粒细胞浸润症、排尿困难以及尿频等。严重的反应[如显著的支气管痉挛、血管神经性水肿(如喉头水肿)以及其它过敏反应等]罕有报道，这些反应有时被称作假过敏。
2.鼻腔内使用可能导致短暂的鼻粘膜刺激症、喷嚏，偶尔出现鼻出血。
3.口服可引起恶心、皮疹和关节痛。
4.本药滴眼引起的短暂的烧灼和螫刺感也偶有报道。
注意事项
1.禁忌症: 对本药过敏者。
2.慎用肝、肾功能不全者。
3.药物对妊娠的影响孕妇慎用。美国药品和食品管理局(FDA)对本药的妊娠安全性分级为B级。
4.药物对哺乳的影响哺乳期妇女慎用。
生产厂家：赛诺菲K.K.External

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Intal Aerosol（Sodium cromoglicate）
Brand name : Intal Aerosol 1 mg
　Active ingredient: Sodium cromoglicate
　Dosage form: aerosol agent
　Print on wrapping: インタールエアロゾル1 mg, 10 mL, サノフィ株式会社
Effects of this medicine
This medicine suppresses allergic symptoms by suppressing release of chemical mediators such as histamine.
It is usually used to treat bronchial asthma.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, inhale 2 sprays (2 mg of the active ingredient) at a time, 4 times a day (morning, noon, evening and before bedtime). If the symptoms improve, the dosage may be reduced 2 to 3 times a day according to the patient's condition. Strictly follow the instructions.
•If you miss a dose, inhale the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never inhale two doses at one time.
•If you accidentally inhale more than your prescribed dose, consult with your doctor or pharmacist.
•Do not stop using this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include rash, throat irritation such as mouth and throat pain or induction of cough, nausea, dry mouth and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•sudden shortness of breath, wheezing (crowing sound), sensation of chest constriction (sensation of chest tightness and pressure) [bronchospasm]
•fever, cough, sputum [PIE syndrome]
•breathing difficulty, hives, angioedema (swelling around the eyes or lips) [anaphylactoid symtoms]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
•Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
•Discard the remainder after emptying the gas. Do not store them.
Sanofi K.K.External
Published: 1/2016
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
http://www.info.pmda.go.jp/go/pack/2259701R2036_2_04/
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产地国家: 日本
原产地英文商品名:
Intal Aerosol（インタールエアロゾル）1mg/vial 5vial/BOx
原产地英文药品名:
Sodium Cromoglicate
原产地英文化合物名称:
Disodium 5,5'‐(2‐hydroxytrimethylenedioxy)bis(4‐oxo‐4H‐1‐enzopyran‐2‐carboxylate）
中文参考商品译名:
Intal Aerosol（インタールエアロゾル）1毫克/瓶  5瓶/盒
中文参考药品译名:
色甘酸钠
生产厂家中文参考译名:
赛诺菲公司
生产厂家英文名:
Sanofi K.K.External