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当前位置:药品说明书与价格首页 >> 呼吸系统病 >> 其他类用药 >> KENBRAN Powder for Inhalation Solution(氯乙酰甲胆碱吸入粉雾剂)

KENBRAN Powder for Inhalation Solution(氯乙酰甲胆碱吸入粉雾剂)

2016-05-24 01:39:27  作者:新特药房  来源:互联网  浏览次数:0  文字大小:【】【】【
简介: 英文药名:KENBRAN Powder for Inhalation Solution(Methacholine chloride) 中文药名:氯乙酰甲胆碱吸入粉雾剂 生产厂家:参天制药 ケンブラン吸入粉末溶解用100mg 治疗类别名称胆碱能药对于 ...

英文药名:KENBRAN Powder for Inhalation Solution(Methacholine chloride)

中文药名:氯乙酰甲胆碱吸入粉雾剂

生产厂家:参天制药

ケンブラン吸入粉末溶解用100mg

治疗类别名称
胆碱能药
对于气道高反应检查
欧文商標名
KENBRAN POWDER FOR INHALATION SOLUTION 100mg
一般名:
メタコリン塩化物 (Methacholine Chloride)
化学名:
(2RS )-2-Acetoxy-N ,N ,N -trimethylpropylaminium chloride
構造式:


分子式:
C8H18ClNO2
分子量:
195.69
性状:
本品是一种白色结晶粉末。
此产品容易溶解在水中,乙醇(99.5)和氯仿。
熔点:
170〜173℃
操作注意事项
如果你对付这种药物,应注意,以免接触到这种药物。
条件批准
在建立药品风险管理计划的顶部,要正确实现
适应病症
气道高反应检查
用法用量
除了甲磺酰氯100毫克(1小瓶)到天站生理盐水溶解并稀释,通常是0.039到制备的适当稀释系列在〜25毫克/毫升的范围内的稀释液。大人和孩子,稀释一系列被吸入使用喷雾器比低浓度的准备,实施气道高反应检查。
药效药理
1. 作用机序
收缩和支气管平滑肌,副交感神经(胆碱能)和管辖,通过迷走神经刺激的支气管分泌物的增加,乙酰胆碱从神经末梢,引起作用于受体释放。胆碱是乙酰胆碱的β型甲基同系物,5作用在直接乙酰胆碱受体)。
如果与哮喘患者吸入含甲胆碱的溶液中,对乙酰甲胆碱的高灵敏度与健康受试者相比时,支气管收缩发生在较低的剂量。在反应这种差异是在对乙酰甲胆碱激发试验的药理基础。
2. 药理作用
乙酰胆碱是通过使在收缩和支气管平滑肌的支气管分泌物的增加,参与了气道阻塞。
包装规格
吸入粉末溶解:
100毫克 100毫克×1瓶
生产(进口)原
参天制药有限公司
许可证结盟
Methapharm特殊药品
完整处方资料附件:http://www.info.pmda.go.jp/go/pack/7290708G1033_1_02/
KENBRAN Powder for Inhalation Solution(Methacholine chloride)
KENBRAN Powder for Inhalation Solution 100mg(ケンブラン吸入粉末溶解用100mg) 
Brand name: KENBRAN Powder for Inhalation Solution 100mg
 Active ingredient: Methacholine chloride
 Dosage form: white powder (Use-time dissolution type inhalation), 100mg, (bottle) brown vial, (cap) deep yellow green
 Print on wrapping: 
Effects of this medicine
This medicine causes contraction of bronchial smooth muscle and increase of bronchial secretion by acting on acetylcholine receptor.
It is usually used for the examination of bronchial airway hyperresponsiveness in case of diagnosis/severity assessment of bronchial asthma.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: airflow limitation (exhalation difficulty), obvious respiratory distress, wheezing (whistling sound), history of myocardial/cerebral infarction within recent 3 months, hypertension, cerebral/aortic aneurysm, hyperthyroidism, cardiovascular disease with bradycardia, peptic ulcer disease, Addison's disease, gastrointestinal/urinary tract obstruction, epilepsy, Parkinsonism, hyperfunction of vagus nerve or myasthenia gravis.
If you have examined bronchial airway hyperresponsiveness on the same day.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, inhale an appropriate series of the diluted solution from low concentration within the limits of 0.039 to 25 mg/mL using a nebulizer. Strictly follow the instructions.
•This medicine is bronchoconstrictor used only for inhalation of the examination of bronchial airway hyperresponsiveness.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include cough, respiratory distress, wheezing (whistling sound), respiratory sounds abnormal and choking sensation. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•breathing difficulty, shortness of breath on exertion [respiratory distress]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

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