部份中文苹果酸电解质处方资料（仅供参考） 苹果酸电解质注射液（Sterofundin ISO） 药品名称：苹果酸电解质注射液 剂  型：注射液 规    格：250 、500、1000ml 德国贝朗,商品名:Sterofundin ISO 药品简介 商品名：Sterofundin ISO 适应症：酸中毒等渗性脱水情况下细胞外液损失的替代物 国内外上市信息：已在香港和德国上市： 香港:B Braun Medical (HK) Ltd. 、DKSH、Four Star 500ml 优势 等渗性脱水，外科病人 *易发生。正常情况下，水和钠成一定比例，血清钠在正常范围，细胞外液渗透压也维持正常。等渗性脱水时，细胞外液量（包括循环血量）迅速减少， *初细胞内液并不向细胞外液间隙转移，细胞内液量并不发生变化，但这种液体丧失持续时间较久后，细胞内液将逐渐外移，随同细胞外液一起丧失，以致引起细胞缺水。大量呕吐、肠瘘、腹腔感染、肠梗阻、烧伤等都可能引起等渗性脱水。等渗性脱水常伴有代谢性酸中毒或碱中毒的一些临床表现。 针对细胞外液量的减少，一般可用等渗盐水或平衡盐液尽快补充血容量。 在重度缺水或休克状态下，肾血流量减少，影响排氯功能，若从静脉大量输给等渗盐水，有导致血Cl- 过高，引起高氯性酸中毒的危险。 因此，应用等渗盐水治疗缺水尚有一些不足之处。 平衡盐溶液的电解质含量和血浆内含量相仿，用来治疗缺水更加符合生理，可以避免输入过多的Cl- ，并对酸中毒的纠正有一定帮助。此外，在纠正缺水后，钾的排泄有所增加，K+浓度也会因细胞外液量增加而被稀释降低，故应注意低钾血症的发生。 本品满足上述要求，可弥补因应用等渗盐水治疗缺水的一些不足之处，不会引起高氯性酸中毒。 L－苹果酸可用于药物片剂、糖浆中，还可以配入氨基酸溶液中，能明显提高氨基酸的吸收率。 STEROFUNDIN ISO Ecoflac Plus Infusionslösung Sterofundin ISO infusion  Sterofundin ISO Inhalt: 10x250  10x500 Milliliter, N2 Anbieter: B. Braun Melsungen AG Darreichungsform: Infusionslösung Manufacturer:  B Braun Distributor: Hong Kong: DKSH              Macau:Four Star Manufacturer B Braun Distributor  B Braun Contents Per 250 mL NaCl 1.6998 g, KCl 0.0746 g, CaCl2 dihydrate 0.0919 g, MgCl2 hexahydrate 0.0508 g, Na acetate trihydrate 0.8165 g, malic acid 0.1678 g Indications Correct disturbances in fluid & electrolyte homeostasis or acid-base balance & re-establish osmotic equilibrium of specific ions. Click to view Sterofundin ISO detailed prescribing infomation Dosage Adult, adolescent & elderly 500 mL to 3 L/day, corresponding to 1-6 mmol Na/kg/day & 0.03-0.17 mmol K/kg/day. Childn & infant 20-100 mL/kg/day, corresponding to 3-14 mmol Na/kg/day & 0.08-0.4 mmol K/kg/day. Ave infusion rate: 5 mL/kg/hr. Click to view Sterofundin ISO detailed prescribing infomation Overdosage View Sterofundin ISO overdosage for action to be taken in the event of an overdose. Contraindications Hypervolemia, severe CHF, renal failure w/ oliguria or anuria, severe general edema, hyperkalemia, hypercalcemia, metabolic alkalosis. Click to view Sterofundin ISO detailed prescribing infomation Special Precautions Mild to moderate cardiac or pulmonary failure, peripheral or pulmonary edema or extracellular hyperhydration, hypernatremia, hyperchloremia, hypertonic dehydration, HTN, renal impairment; present or imminent eclampsia, aldosteronism or other conditions or treatment associated w/ Na retention; conditions predisposing to hyperkalemia eg renal or adrenocortical insufficiency, acute dehydration or extensive tissue destruction; extravasation, sarcoidosis, concomitant blood transfusion; resp impairment, nutritive supply for long-term treatment. Monitor serum electrolytes, fluid balance & pH. Pregnancy & lactation. Click to view Sterofundin ISO detailed prescribing infomation Adverse Drug Reactions Febrile response, infection at the inj site, local pain or reaction, vein irritation, venous thrombosis or phlebitis. View ADR Monitoring Website Drug Interactions Corticosteroids & carbenoxolone; suxamethonium, K-sparing diuretics; tacrolimus, cyclosporine; digitalis glycosides, carbonate-, phosphate-, sulphate- or tartrate-containing medications. View more drug interactions with Sterofundin ISO Caution For Usage For caution against possible variation of physical aspect of medicine... click to view Sterofundin ISO detailed prescribing infomation Storage View Sterofundin ISO storage conditions for details to ensure optimal shelf-life. Description View Sterofundin ISO description for details of the chemical structure and excipients (inactive components). Mechanism of Action View Sterofundin ISO mechanism of action for pharmacodynamics and pharmacokinetics details. MIMS Class Intravenous & other sterile solutions ATC Classification B05BB01 - electrolytes ; Belongs to the class of solutions affecting the electrolyte balance used in I.V. solutions. Poison Schedule。 Rx Sterofundin ISO solution for infusion 产地国家: 德国 Sterofundin ISO Ecoflac Plus Infusionslösung 10x 250Milliliter, N2 Sterofundin ISO Ecoflac Plus Infusionslösung 10 x 500Milliliter, N2 Sterofundin ISO Ecoflac Plus Infusionslösung 10x 1000Milliliter, N2