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FOSAMAX PLUS(福善美加D片
药品信息:
默克公司４月８日宣布，美国ＦＤＡ已经批准了该公司新药ＦＯＳＡＭＡＸ ＰＬＵＳ Ｄ的上市申请。ＦＯＳＡＭＡＸ ＰＬＵＳ Ｄ为骨质疏松治疗药物，含有７０ｍｇ福善美（ＦＯＳＡＭＡＸ，阿仑膦酸钠）和２８００ ＩＵ维生素Ｄ３，每周只需服用一次。福善美主要于绝经后患有骨质疏松症的妇女，能够降低髋部和脊柱骨折的发生率，是目前唯一一个和一周用量的维生素Ｄ３配伍的双磷酸化合物类药物。
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How Do I Know FOSAMAX or FOSAMAX PLUS D is Working?
You will not feel it working, but you and your doctor can monitor your progress with a bone mineral density test prescribed by your doctor. Ninety-six percent of patients, on either a once-daily or once-weekly schedule, increased or maintained bone mass.
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How Long Do I Take FOSAMAX or FOSAMAX PLUS D?
Only your doctor can determine how long you should keep taking FOSAMAX or FOSAMAX PLUS D. The effects will continue as long as you continue treatment. For most patients, that means your bone density will be maintained or increased and your bones will be less likely to fracture.
If you experience side effects, call your doctor right away.
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Selected Cautionary Information About FOSAMAX and FOSAMAX PLUS D
You should not use FOSAMAX or FOSAMAX PLUS D if you have certain disorders of the esophagus (the tube connecting the mouth with the stomach), are not able to stand or sit upright for 30 minutes, have severe kidney disease, low blood calcium, or are allergic to FOSAMAX or FOSAMAX PLUS D. Before use, talk to your doctor if you have or have had stomach or digestive problems or problems with swallowing. You should tell your doctor about all medicines you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements. In addition, for FOSAMAX PLUS D, you should talk to your doctor if you have conditions that may cause an overproduction of vitamin D (eg, sarcoidosis, leukemia, lymphoma).
Stop taking FOSAMAX or FOSAMAX PLUS D and call your doctor right away if you develop new or worsening heartburn, difficult or painful swallowing, or chest pain because these may be signs of serious upper digestive problems, which can include irritation, inflammation, or ulceration of the esophagus. (See the Patient Product Information for more details.) If you develop severe bone, joint, and/or muscle pain at any time, contact your doctor. FOSAMAX AND FOSAMAX PLUS D may cause jawbone problems in some people. Jawbone problems may include infection, and delayed healing after teeth are pulled. Digestive side effects in studies were generally mild and included stomach pain, indigestion/heartburn, or nausea.
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How to Take FOSAMAX 35-mg or 70-mg Once-Weekly Tablets, FOSAMAX 70-mg Once-Weekly Oral Solution, and FOSAMAX PLUS D 70-mg/2,800 IU Once-Weekly Tablets
Choose a day of the week that best fits your schedule. Take 1 FOSAMAX or FOSAMAX PLUS D dose on your chosen day, every week.
Tablets: Swallow 1 FOSAMAX or FOSAMAX PLUS D tablet with 6 to 8 ounces of plain water first thing in the morning before you have anything to eat or drink.
OR
Oral Solution: Drink 1 entire bottle of solution followed by at least 2 ounces (a quarter of a cup) of plain water.
Begin the day’s activities, but don’t lie down, eat, drink, or take other medications for at least 30 minutes. If you want to lie down after 30 minutes, you must eat breakfast first.
If you miss a dose, take only 1 dose of FOSAMAX or FOSAMAX PLUS D on the morning after you remember. Do not take 2 doses on the same day.
Continue your usual schedule of 1 dose once a week on your chosen day.
How to Take FOSAMAX 5-mg or 10-mg Tablets Once-Daily
Take FOSAMAX with 6 to 8 oz of plain water first thing in the morning before you have anything to eat or drink. Begin the day’s activities, but don’t lie down, eat, drink, or take other medications for at least 30 minutes. If you want to lie down after 30 minutes, you must eat breakfast first.
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How to Take FOSAMAX 5-mg or 10-mg Tablets Once-Daily
Take FOSAMAX with 6 to 8 oz of plain water first thing in the morning before you have anything to eat or drink. Begin the day’s activities, but don’t lie down, eat, drink, or take other medications for at least 30 minutes. If you want to lie down after 30 minutes, you must eat breakfast first.
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Selected Cautionary Information About FOSAMAX and FOSAMAX PLUS D
You should not use FOSAMAX or FOSAMAX PLUS D if you have certain disorders of the esophagus (the tube connecting the mouth with the stomach), are not able to stand or sit upright for 30 minutes, have severe kidney disease, low blood calcium, or are allergic to FOSAMAX. Before use, talk to your doctor if you have stomach or digestive problems. You should tell your doctor about all medicines you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
In addition, for FOSAMAX PLUS D, you should talk to your doctor if you have conditions that may cause an overproduction of vitamin D (eg, sarcoidosis, leukemia, and lymphoma).
学名：阿仑膦酸钠（阿仑膦酸钠）
商品牌子名：
福善美®（福善美®）;
福善美®每周一次（每周福善美®）;
福善美PLUS ®的（福善美加®）
药物制造商：
美国默沙东药厂有限公司
剂型：药片
（70毫克阿仑膦酸盐2800国际单位维他命D3的） 与70mg/5600IU
孕妇用药分级中：C
药理：
阿仑膦酸盐（阿仑膦酸钠）属双磷酸盐类药物（二膦酸盐），可与骨骼中的氢氧磷灰石（羟基磷灰石）结合，从而阻碍破骨细胞（破骨细胞）对骨骼所产生之溶蚀作用。能防止骨质流失及重建骨骼，令骨质密度增加，减少骨折的机会。
用途：
治疗患有骨质疏松症的男性;治疗因为服用类固醇而引致的骨质疏松症，预防及治疗更年期后妇女骨质疏松症。
剂量：
10毫克药片：
每日服用一次，每次一粒。
70毫克药片：
每周服用一次，每次一粒。
用药禁忌：
升食道（连接口腔和胃部的管道）有毛病。
升对此药的任何成份敏感。
升血液含钙量过低。
升不能维持挺直站立或坐直至少三十分钟。
用药注意：
升此药在空肚时服食才能发挥作用。服用后，除清水外，至少等候三十分钟才能进食，饮料或服食其他药物，包括抗酸剂，钙片及维他命。
升请勿咀嚼药片或把药片含在嘴里舔吃。
升若你发现进食时感到困难或痛楚，感到胸口痛，胸口灼热或其情况加剧，请立即通知你的医生。
升若你忘记定时每日服用10毫克药片，请勿在当日其他时间补服，只需在翌晨服用药片一粒，请勿在同一天服食两粒。
升若你忘记服用70毫克药片，只需在翌晨服用药片一粒。请勿在同一天补服两粒每周福善美。请继续按照原预先服药的安排，在选定的日子，每星期服用药片一次，每次一粒。
常见副作用：
肠胃不适，例如恶心，呕吐。
其他副作用：
升一些消化系统的不适，可能会比较严重，包括因食道（连接口和胃的管道）受刺激或溃疡而产生胸口痛，胸口灼热又或吞咽困难或痛楚。若病人没有以一整杯清水服用和/或若病人在服药后三十分钟内躺下，或不是在早餐前服用此药，比较容易引致以上的副作用。
升在服药后会有骨痛，肌肉或关节痛（有些病人会罕有地同时出现类似感冒的症状或发烧），或罕见地会出疹（阳光偶尔会令其情况恶化）痕痒或眼痛。
药物相互作用：
服用药片后，除清水外，至少等候三十分钟才能进食，饮料或服食其他药物，包括抗酸剂，钙片及维他命。
病患者及家属注意事项：
升起床后以一满杯清水（请勿以矿泉水，咖啡，茶或果汁代替）吞服阿仑膦酸盐药片。
升请勿咀嚼药片或把药片含在嘴里舔吃。
升若你正怀孕或喂养母乳，请勿服用此药。
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产地国家: 美国
原产地英文商品名:
FOSAMAX PLUS D(ALENDRONATE SODIUM/CHOLECALCIFEROL))70 MG/5600IU X 4Tabs
原产地英文药品名:
ALENDRONATE SODIUM/CHOLECALCIFEROL
中文参考商品译名:
阿仑膦酸钠/维生素D3 70毫克/5600单位 4片/盒
中文参考药品译名:
阿仑膦酸钠/维生素D3
生产厂家中文参考译名:
默克制药
生产厂家英文名:
MERCK
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原产地英文商品名:
FOSAMAX PLUS D(ALENDRONATE SODIUM/CHOLECALCIFEROL))70 MG/2800IU X 4Tabs
原产地英文药品名:
ALENDRONATE SODIUM/CHOLECALCIFEROL
中文参考商品译名:
阿仑膦酸钠/维生素D3 70毫克/2800单位 4片/盒
中文参考药品译名:
阿仑膦酸钠/维生素D3
生产厂家中文参考译名:
默克制药
生产厂家英文名:
MERCK
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