英文药名: Kayexalate(Sodium Polystyrene Sulfonate Powder)
中文药名: 聚苯乙烯磺酸钠粉
生产厂家: Sanofi-Synthelabo
给药说明 药物名称: 聚磺苯乙烯 药物别名: 降钾树脂,聚苯乙烯磺酸钠,KAYEXALATE,RERONIUM-A 英文名称: Polystyrene Sulfonate
适应症 本品试用于治疗急慢性肾功能衰竭、肾病综合征、狼疮性肾炎、肝肾综合征等并发的高钾血症(血钾>5.5mmol/L者),证明有明显疗效,血钾下降幅度为0.5~1mmol/L或更多,且无显著副作用。 用法用量 口服:成人每次15~30g,事先可用水调匀,每日服1~2次或遵医嘱。若有便秘,可与甘露醇粉或山梨醇粉等量同时服用。儿童参考剂量每天按1g/kg计算。 直肠给药:每次30g,每天1~2次,用水或20%甘露醇100~200ml混匀作高位保留灌肠。
注意事项 (1)副作用轻微,少数患者可发生轻度恶心、呕吐、血压升高、便秘等症状。 (2)有严重高血压及心力衰竭者慎用。 (3)治疗期间应经常测定血钾水平,避免血钾过低,血钾降至4.5mmol/L时即应停药。
Generic Name for KAYEXALATE Sodium polystyrene sulfonate; pwd; sodium content 4.1mEq/g.
Legal Classification: Rx
Pharmacological Class for KAYEXALATE Cation exchange resin.
Manufacturer of KAYEXALATE Sanofi Aventis Indications for KAYEXALATE Hyperkalemia.
Adult dose for KAYEXALATE See literature. Oral: 15g 1–4 times daily, as a susp. Rectal enema: 30–50g in 100mL every 6 hrs.
Children's dosing for KAYEXALATE See literature. Use 1g per 1mEq of potassium as basis of calculation.
Contraindications for KAYEXALATE Hypokalemia. Obstructive bowel disease. Neonates.
Warnings/Precautions for KAYEXALATE Hypokalemia. Monitor electrolytes, ECG. Hypernatremia. CHF. Hypertension. Edema. Risk of constipation/impaction (eg, history of impaction, chronic constipation, inflammatory bowel disease, ischemic colitis, vascular intestinal atherosclerosis, previous bowel resection, bowel obstruction); discontinue if significant constipation develops. Monitor for intestinal necrosis (esp. in children). Pregnancy (Cat.C). Nursing mothers.
Interactions for KAYEXALATE Avoid non-adsorbable cation donating antacids and laxatives (eg, magnesium hydroxide, aluminum hydroxide). Sorbitol may cause intestinal necrosis (concomitant use not recommended). Digoxin toxicity potentiated by hypokalemia. Reduces absorption of thyroxine, lithium.
Adverse Reactions for KAYEXALATE GI irritation/ulceration/necrosis, sodium retention, hypokalemia, hypocalcemia, hypomagnesemia, fecal impaction, ischemic colitis.
How is KAYEXALATE supplied? Jar (453g)—1
Related Disease: Poisoning/overdose
KAYEXALATE(ケイキサレートドライシロップ76% )品名 英文:KAYEXALATE DRYSYRUP 76% ケイキサレートドライシロップ76% 聚苯乙烯磺酸钠 日文:ケイキサレートドライシロップ76% 中文:聚苯乙烯磺酸钠 有效成分 英文:Sodium Polystyrene Sulfonate 日文:ポリスチレンスルホン酸ナトリウム 中文:聚苯乙烯磺酸钠 生产厂家:鸟居药品 适合病症:急性和慢性肾功能衰竭的高钾血症 批准上市时间:2011年2月: 药品形状:颗粒 最小包装单位容量:盒
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